Hypoxia-Inducible Factor 1
"Hypoxia-Inducible Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that plays a role in APOPTOSIS. It is composed of two subunits: ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR and HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT.
| Descriptor ID |
D051793
|
| MeSH Number(s) |
D12.776.260.103.625 D12.776.930.125.625
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1" by people in this website by year, and whether "Hypoxia-Inducible Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 2 | 3 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1" by people in Profiles.
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MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia. Epigenetics. 2022 12; 17(13):2056-2074.
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Hypoxia-inducible factors and obstructive sleep apnea. J Clin Invest. 2020 10 01; 130(10):5042-5051.
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2019 Nobel Prize in Physiology or Medicine. Physiology (Bethesda). 2020 03 01; 35(2):81-83.
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Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma. Cancer Res. 2019 10 15; 79(20):5218-5232.
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Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1. PLoS Pathog. 2018 11; 14(11):e1007394.
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Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome. J Mol Med (Berl). 2015 May; 93(5):473-80.
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The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation. J Clin Invest. 2014 Jun; 124(6):2640-50.
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Hypoxia-inducible factors regulate human and rat cystathionine ß-synthase gene expression. Biochem J. 2014 Mar 01; 458(2):203-11.
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Expression of HIF-1 regulated proteins vascular endothelial growth factor, carbonic anhydrase IX and hypoxia inducible gene 2 in hemangioblastomas. Folia Neuropathol. 2014; 52(3):234-42.
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ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. PLoS One. 2013; 8(2):e56949.