Autophagy-Related Protein 5
"Autophagy-Related Protein 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
| Descriptor ID |
D000071187
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| MeSH Number(s) |
D12.776.094.250
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| Concept/Terms |
Autophagy-Related Protein 5- Autophagy-Related Protein 5
- Autophagy Related Protein 5
- Apoptosis-Specific Protein
- Apoptosis Specific Protein
- ATG5 Protein
- ATG-5 Protein
- ATG 5 Protein
- Autophagy Protein-5
- Autophagy Protein 5
- Autophagy-Related 5 Protein
- Autophagy Related 5 Protein
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 5".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 5".
This graph shows the total number of publications written about "Autophagy-Related Protein 5" by people in this website by year, and whether "Autophagy-Related Protein 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 5" by people in Profiles.
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Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing. Autophagy. 2021 09; 17(9):2128-2143.
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Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy. Autophagy. 2017; 13(11):1905-1923.
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A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction. Brain. 2017 Apr 01; 140(4):1128-1146.
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Soluble bioactive microbial mediators regulate proteasomal degradation and autophagy to protect against inflammation-induced stress. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G634-G647.
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Intracellular HMGB1: defender of client proteins and cell fate. Oncotarget. 2015 Apr 20; 6(11):8432-3.
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Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation. J Clin Invest. 2015 Mar 02; 125(3):1098-110.
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Measuring autophagy in stressed cells. Methods Mol Biol. 2015; 1292:129-50.
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The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy. Immunity. 2014 Jun 19; 40(6):924-35.
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Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma. Cell Host Microbe. 2012 Apr 19; 11(4):397-409.
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In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 2010 Feb 26; 32(2):227-39.