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PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21.
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PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21.
PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21. Oncotarget. 2015 Jul 30; 6(21):18469-83.
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PubMed
subject areas
Autophagy
Blotting, Western
Cantharidin
CDC2 Protein Kinase
Cell Line, Tumor
Cyclin-Dependent Kinase Inhibitor p21
Down-Regulation
Enzyme Inhibitors
G2 Phase Cell Cycle Checkpoints
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
JNK Mitogen-Activated Protein Kinases
MCF-7 Cells
Okadaic Acid
Oligonucleotide Array Sequence Analysis
Promoter Regions, Genetic
Protein Phosphatase 2
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
Signal Transduction
Sp1 Transcription Factor
Up-Regulation
authors with profiles
Bin Zhou