"alpha-2-Antiplasmin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are induced by plasminogen activator. It is a glycoprotein, molecular weight approximately 70,000 that migrates in the alpha 2 region in immunoelectrophoresis. It is the principal plasmin inactivator in blood, rapidly forming a very stable complex with plasmin.
| Descriptor ID |
D000979
|
| MeSH Number(s) |
D12.644.861.050 D12.776.124.790.106.090 D12.776.377.715.085.090 D12.776.395.080 D12.776.872.050
|
| Concept/Terms |
alpha-2-Antiplasmin- alpha-2-Antiplasmin
- Serpin F2
- alpha-2 Antiplasmin
- alpha 2 Antiplasmin
- alpha 2-Plasmin Inhibitor
- alpha 2 Plasmin Inhibitor
- alpha(2)-Plasmin Inhibitor
|
Below are MeSH descriptors whose meaning is more general than "alpha-2-Antiplasmin".
Below are MeSH descriptors whose meaning is more specific than "alpha-2-Antiplasmin".
This graph shows the total number of publications written about "alpha-2-Antiplasmin" by people in this website by year, and whether "alpha-2-Antiplasmin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "alpha-2-Antiplasmin" by people in Profiles.
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Tranexamic acid administration in the field does not affect admission thromboelastography after traumatic brain injury. J Trauma Acute Care Surg. 2020 11; 89(5):900-907.
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Engineered insulin-like growth factor-1 for improved smooth muscle regeneration. Biomaterials. 2012 Jan; 33(2):494-503.
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Cell-demanded liberation of VEGF121 from fibrin implants induces local and controlled blood vessel growth. Circ Res. 2004 Apr 30; 94(8):1124-32.
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Chimerism reveals a role for the streptokinase Beta -domain in nonproteolytic active site formation, substrate, and inhibitor interactions. J Biol Chem. 2002 Jul 26; 277(30):26846-51.
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Development of fibrin derivatives for controlled release of heparin-binding growth factors. J Control Release. 2000 Apr 03; 65(3):389-402.
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Decreased platelet number and function and increased fibrinolysis contribute to postoperative bleeding in cardiopulmonary bypass patients. Thromb Haemost. 1988 Feb 25; 59(1):62-7.
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Effects of protease inhibitors on coagulation abnormalities in acute canine pancreatitis. Am Surg. 1984 Jun; 50(6):317-23.