"alpha 1-Antitrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
| Descriptor ID |
D000515
|
| MeSH Number(s) |
D12.644.861.035 D12.776.124.050.070 D12.776.124.790.106.085 D12.776.377.715.085.085 D12.776.395.068 D12.776.872.035
|
| Concept/Terms |
alpha 1-Antitrypsin- alpha 1-Antitrypsin
- alpha 1 Antitrypsin
- alpha 1 Antiprotease
- Antiprotease, alpha 1
- Serpin A1
- alpha 1-Protease Inhibitor
- Inhibitor, alpha 1-Protease
- alpha 1 Protease Inhibitor
- alpha 1-Proteinase Inhibitor
- Inhibitor, alpha 1-Proteinase
- alpha 1 Proteinase Inhibitor
- Trypsin Inhibitor, alpha 1-Antitrypsin
- Trypsin Inhibitor, alpha 1 Antitrypsin
- A1PI
- alpha 1-Antiproteinase
- 1-Antiproteinase, alpha
- alpha 1 Antiproteinase
|
Below are MeSH descriptors whose meaning is more general than "alpha 1-Antitrypsin".
Below are MeSH descriptors whose meaning is more specific than "alpha 1-Antitrypsin".
This graph shows the total number of publications written about "alpha 1-Antitrypsin" by people in this website by year, and whether "alpha 1-Antitrypsin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "alpha 1-Antitrypsin" by people in Profiles.
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Efficacy and safety of the Spiration Valve System™ for the treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE). Respir Med. 2024 04; 224:107565.
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HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
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Targeted Measurements of O- and N-Glycopeptides Show That Proteins in High Density Lipoprotein Particles Are Enriched with Specific Glycosylation Compared to Plasma. J Proteome Res. 2018 02 02; 17(2):834-845.
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The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction. COPD. 2012 Aug; 9(4):352-8.
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Development and characterization of reference materials for MTHFR, SERPINA1, RET, BRCA1, and BRCA2 genetic testing. J Mol Diagn. 2009 Nov; 11(6):553-61.
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Keratectasia after laser in situ keratomileusis: a histopathologic and immunohistochemical study. Arch Ophthalmol. 2008 Dec; 126(12):1655-63.
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Issues in the diagnosis of alpha 1-antitrypsin deficiency. J Allergy Clin Immunol. 2008 Apr; 121(4):833-8.
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Sequence diversity at the proximal 14q32.1 SERPIN subcluster: evidence for natural selection favoring the pseudogenization of SERPINA2. Mol Biol Evol. 2007 Feb; 24(2):587-98.
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Proteolytic processing of familial British dementia-associated BRI variants: evidence for enhanced intracellular accumulation of amyloidogenic peptides. J Biol Chem. 2002 Jan 18; 277(3):1872-7.
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Haemocompatibility of paediatric membrane oxygenators with heparin-coated surfaces. Perfusion. 1999 Jan; 14(1):21-8.