Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet.

Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. Diabetes. 2011 Nov; 60(11):2843-52.

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subject areas

Animals
Cell Line
Diabetes Mellitus, Type 2
Enzyme Activation
Humans
Hyperglycemia
Islets of Langerhans
Isoenzymes
JNK Mitogen-Activated Protein Kinases
Male
Middle Aged
Mitochondria
NADPH Oxidases
Oxidative Stress
Phosphorylation
Protein Kinase Inhibitors
Protein Processing, Post-Translational
rac1 GTP-Binding Protein
Rats
Rats, Zucker
Reactive Oxygen Species
Signal Transduction
Tissue Culture Techniques

authors with profiles

Christopher J. Rhodes