"Protamines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
| Descriptor ID |
D011479
|
| MeSH Number(s) |
D12.776.660.750 D12.776.664.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protamines".
Below are MeSH descriptors whose meaning is more specific than "Protamines".
This graph shows the total number of publications written about "Protamines" by people in this website by year, and whether "Protamines" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protamines" by people in Profiles.
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Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation. Cell Metab. 2019 11 05; 30(5):865-876.e5.
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Protamine Administration Via the Ascending Aorta May Prevent Cardiopulmonary Instability. J Cardiothorac Vasc Anesth. 2016 Jun; 30(3):647-55.
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Effects of a fixed mixture of 25% insulin lispro and 75% NPL on plasma glucose during and after moderate physical exercise in patients with type 2 diabetes. Curr Med Res Opin. 2002; 18(4):188-93.
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The effect on the hemodynamic stability of varying calcium chloride administration during protamine infusion in pediatric open-heart patients. Anesth Analg. 2001 Jul; 93(1):92-5, TOC.
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Vascular or interventional procedures in patients with diabetes. J Vasc Interv Radiol. 1997 Nov-Dec; 8(6):1080.
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Effects of aprotinin on anticoagulant monitoring: implications in cardiovascular surgery. Ann Thorac Surg. 1993 Mar; 55(3):662-6.
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Effect of polycations on prostaglandin synthesis in cultured glomerular mesangial cells. Biochim Biophys Acta. 1990 Feb 06; 1042(2):221-6.
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Failure of automated protamine titration to determine the protamine reversal dose of systemic heparin: comparison with other methods. Curr Surg. 1986 Mar-Apr; 43(2):110-2.
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A comparison of methods to calculate the heparin reversal dose of protamine in cardiovascular surgery. Trans Am Soc Artif Intern Organs. 1985; 31:143-5.
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Influence of heparin and protamine on enlargement of the draining lymph node during induction of EAE. Cell Immunol. 1974 Jun; 12(3):345-9.