"Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.
| Descriptor ID |
D000682
|
| MeSH Number(s) |
D05.500.049 D12.776.049
|
| Concept/Terms |
Amyloid- Amyloid
- Amyloid Substance
- Substance, Amyloid
|
Below are MeSH descriptors whose meaning is more general than "Amyloid".
Below are MeSH descriptors whose meaning is more specific than "Amyloid".
This graph shows the total number of publications written about "Amyloid" by people in this website by year, and whether "Amyloid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 2 | 4 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 0 | 2 |
| 1999 | 2 | 1 | 3 |
| 2000 | 2 | 1 | 3 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 3 | 0 | 3 |
| 2006 | 3 | 1 | 4 |
| 2007 | 1 | 0 | 1 |
| 2009 | 4 | 2 | 6 |
| 2010 | 1 | 2 | 3 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Amyloid" by people in Profiles.
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Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly. Nat Cell Biol. 2021 10; 23(10):1085-1094.
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Glycosylation of a Nonfibrillizing Appendage Alters the Self-Assembly Pathway of a Synthetic ?-Sheet Fibrillizing Peptide. J Phys Chem B. 2021 06 24; 125(24):6559-6571.
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Alternatives to amyloid for Alzheimer's disease therapies-a symposium report. Ann N Y Acad Sci. 2020 09; 1475(1):3-14.
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Pancreatic ductal adenocarcinoma is associated with a unique endocrinopathy distinct from type 2 diabetes mellitus. Pancreatology. 2020 Jul; 20(5):929-935.
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Anatomy of a selectively coassembled ?-sheet peptide nanofiber. Proc Natl Acad Sci U S A. 2020 03 03; 117(9):4710-4717.
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Amylin as a Potential Link between Type 2 Diabetes and Alzheimer Disease. Ann Neurol. 2020 03; 87(3):486.
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Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries. Kidney Int. 2020 01; 97(1):143-155.
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Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models. Brain Pathol. 2019 07; 29(4):485-501.
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Chaperone AMPylation modulates aggregation and toxicity of neurodegenerative disease-associated polypeptides. Proc Natl Acad Sci U S A. 2018 05 29; 115(22):E5008-E5017.
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Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. Nat Struct Mol Biol. 2018 04; 25(4):341-346.