 Fibronectins
"Fibronectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
| Descriptor ID |
D005353
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| MeSH Number(s) |
D12.776.377.715.390 D12.776.395.550.350 D12.776.543.550.350 D12.776.860.300.450
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| Concept/Terms |
Fibronectins- Fibronectins
- Opsonic alpha(2)SB Glycoprotein
- Opsonic Glycoprotein
- Glycoprotein, Opsonic
- LETS Proteins
- Proteins, LETS
- alpha 2-Surface Binding Glycoprotein
- alpha 2 Surface Binding Glycoprotein
- Fibronectin
- Cold-Insoluble Globulins
- Cold Insoluble Globulins
- Globulins, Cold-Insoluble
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Below are MeSH descriptors whose meaning is more general than "Fibronectins".
Below are MeSH descriptors whose meaning is more specific than "Fibronectins".
This graph shows the total number of publications written about "Fibronectins" by people in this website by year, and whether "Fibronectins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1981 | 2 | 0 | 2 | | 1987 | 2 | 0 | 2 | | 1988 | 2 | 0 | 2 | | 1991 | 1 | 1 | 2 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 1 | 1 | 2 | | 1996 | 1 | 1 | 2 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 3 | 2 | 5 | | 2002 | 1 | 2 | 3 | | 2003 | 2 | 0 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 3 | 2 | 5 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 3 | 0 | 3 | | 2010 | 3 | 1 | 4 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 2 | 5 | | 2014 | 2 | 3 | 5 | | 2015 | 2 | 1 | 3 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 2 | 3 |
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Below are the most recent publications written about "Fibronectins" by people in Profiles.
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Johnson MB, Pang B, Gardner DJ, Niknam-Benia S, Soundarajan V, Bramos A, Perrault DP, Banks K, Lee GK, Baker RY, Kim GH, Lee S, Chai Y, Chen M, Li W, Kwong L, Hong YK, Wong AK. Topical Fibronectin Improves Wound Healing of Irradiated Skin. Sci Rep. 2017 06 20; 7(1):3876.
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Deb DK, Chen Y, Sun J, Wang Y, Li YC. ATP-citrate lyase is essential for high glucose-induced histone hyperacetylation and fibrogenic gene upregulation in mesangial cells. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F423-F429.
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Ramirez-San Juan GR, Oakes PW, Gardel ML. Contact guidance requires spatial control of leading-edge protrusion. Mol Biol Cell. 2017 Apr 15; 28(8):1043-1053.
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Julier Z, de Titta A, Grimm AJ, Simeoni E, Swartz MA, Hubbell JA. Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses. Vaccine. 2016 05 05; 34(21):2453-2459.
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Shiobara T, Chibana K, Watanabe T, Arai R, Horigane Y, Nakamura Y, Hayashi Y, Shimizu Y, Takemasa A, Ishii Y. Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells. Respir Res. 2016 Mar 14; 17:28.
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Guzmán Prieto AM, Urbanus RT, Zhang X, Bierschenk D, Koekman CA, van Luit-Asbroek M, Ouwerkerk JP, Pape M, Paganelli FL, Wobser D, Huebner J, Hendrickx AP, Bonten MJ, Willems RJ, van Schaik W. The N-terminal domain of the thermo-regulated surface protein PrpA of Enterococcus faecium binds to fibrinogen, fibronectin and platelets. Sci Rep. 2015 Dec 17; 5:18255.
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Bernau K, Ngam C, Torr EE, Acton B, Kach J, Dulin NO, Sandbo N. Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis. Respir Res. 2015 Mar 27; 16:45.
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Julier Z, Martino MM, de Titta A, Jeanbart L, Hubbell JA. The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine. Sci Rep. 2015 Feb 24; 5:8569.
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Kenny HA, Chiang CY, White EA, Schryver EM, Habis M, Romero IL, Ladanyi A, Penicka CV, George J, Matlin K, Montag A, Wroblewski K, Yamada SD, Mazar AP, Bowtell D, Lengyel E. Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion. J Clin Invest. 2014 Oct; 124(10):4614-28.
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Lamplot JD, Angeline M, Angeles J, Beederman M, Wagner E, Rastegar F, Scott B, Skjong C, Mass D, Kang R, Ho S, Shi LL. Distinct effects of platelet-rich plasma and BMP13 on rotator cuff tendon injury healing in a rat model. Am J Sports Med. 2014 Dec; 42(12):2877-87.
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