"CD58 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins with a wide distribution on hematopoietic and non-hematopoietic cells and strongly expressed on MACROPHAGES. CD58 mediates cell adhesion by binding to CD2; (CD2 ANTIGENS); and this enhances antigen-specific T-cell activation.
Descriptor ID |
D018968
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MeSH Number(s) |
D12.776.395.550.034 D12.776.543.550.158
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Concept/Terms |
CD58 Antigens- CD58 Antigens
- CD58 Antigen
- Antigen, CD58
- LFA-3
- Antigens, CD58
- Lymphocyte Function Associated Antigen-3
- Lymphocyte Function Associated Antigen 3
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Below are MeSH descriptors whose meaning is more general than "CD58 Antigens".
Below are MeSH descriptors whose meaning is more specific than "CD58 Antigens".
This graph shows the total number of publications written about "CD58 Antigens" by people in this website by year, and whether "CD58 Antigens" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 2 | 2 |
1998 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD58 Antigens" by people in Profiles.
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A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion. EMBO J. 1998 Dec 15; 17(24):7320-36.
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ICAM-1 and LFA-3 enhance the ability of anti-CD3 mAb to stimulate interferon gamma production in interleukin-2-activated T cells. Cancer Immunol Immunother. 1994 Aug; 39(2):127-34.
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CD54/ICAM-1 is a costimulator of NK cell-mediated cytotoxicity. Cell Immunol. 1994 Aug; 157(1):92-105.
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Monoclonal antibodies anti-CD3, anti-TCR alpha beta and anti-CD2 act synergistically with tumor cells to stimulate lymphokine-activated killer cells and tumor-infiltrating lymphocytes to secrete interferon gamma. Cancer Immunol Immunother. 1992; 35(5):335-41.
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Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and maps to chromosome 1q21-23. J Exp Med. 1989 Mar 01; 169(3):1087-99.