"Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
Below are MeSH descriptors whose meaning is more general than "Protein C".
Below are MeSH descriptors whose meaning is more specific than "Protein C".
This graph shows the total number of publications written about "Protein C" by people in this website by year, and whether "Protein C" was a major or minor topic of these publications.
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|Year||Major Topic||Minor Topic||Total|
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Below are the most recent publications written about "Protein C" by people in Profiles.
Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice. Blood. 2019 01 17; 133(3):193-204.
Protein C activity and postoperative metabolic liver function after liver transplantation. Transplant Proc. 2012 Jun; 44(5):1336-40.
A case series of drotrecogin alfa (activated) in lung transplant recipients. Transplantation. 2006 Jun 27; 81(12):1739-42.
A blueprint for a sepsis protocol. Acad Emerg Med. 2005 Apr; 12(4):352-9.
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation. J Biol Chem. 2005 Apr 29; 280(17):17286-93.
Mathematical models of the acute inflammatory response. Curr Opin Crit Care. 2004 Oct; 10(5):383-90.
Solid-organ transplant recipients treated with drotrecogin alfa (activated) for severe sepsis. Transplantation. 2003 Mar 27; 75(6):899-901.
Hemostatic abnormalities in untreated cancer: incidence and correlation with thrombotic and hemorrhagic complications. J Clin Oncol. 1987 Dec; 5(12):1998-2003.