 Trypsin
"Trypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
| Descriptor ID |
D014357
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| MeSH Number(s) |
D08.811.277.656.300.760.895 D08.811.277.656.959.350.895
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trypsin".
Below are MeSH descriptors whose meaning is more specific than "Trypsin".
This graph shows the total number of publications written about "Trypsin" by people in this website by year, and whether "Trypsin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 1 | 2 | | 1981 | 1 | 0 | 1 | | 1982 | 2 | 0 | 2 | | 1983 | 1 | 3 | 4 | | 1984 | 1 | 1 | 2 | | 1985 | 1 | 2 | 3 | | 1986 | 0 | 2 | 2 | | 1987 | 0 | 2 | 2 | | 1988 | 2 | 5 | 7 | | 1989 | 0 | 3 | 3 | | 1990 | 1 | 2 | 3 | | 1991 | 0 | 1 | 1 | | 1992 | 2 | 3 | 5 | | 1993 | 1 | 2 | 3 | | 1995 | 1 | 5 | 6 | | 1996 | 1 | 2 | 3 | | 1997 | 1 | 1 | 2 | | 1998 | 0 | 1 | 1 | | 2002 | 1 | 4 | 5 | | 2003 | 1 | 2 | 3 | | 2004 | 1 | 2 | 3 | | 2005 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trypsin" by people in Profiles.
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Waldbauer J, Zhang L, Rizzo A, Muratore D. diDO-IPTL: A Peptide-Labeling Strategy for Precision Quantitative Proteomics. Anal Chem. 2017 11 07; 89(21):11498-11504.
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Chellan B, Reardon CA, Getz GS, Hofmann Bowman MA. Enzymatically Modified Low-Density Lipoprotein Promotes Foam Cell Formation in Smooth Muscle Cells via Macropinocytosis and Enhances Receptor-Mediated Uptake of Oxidized Low-Density Lipoprotein. Arterioscler Thromb Vasc Biol. 2016 06; 36(6):1101-13.
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Claud EC, McDonald JA, He SM, Yu Y, Duong L, Sun J, Petrof EO. Differential expression of 26S proteasome subunits and functional activity during neonatal development. Biomolecules. 2014 Aug 29; 4(3):812-26.
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Solomon S, Gelrud A, Whitcomb DC. Low penetrance pancreatitis phenotype in a Venezuelan kindred with a PRSS1 R122H mutation. JOP. 2013 Mar 10; 14(2):187-9.
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Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.
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Toyama A, Nakagawa H, Matsuda K, Sato TA, Nakamura Y, Ueda K. Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring. Anal Chem. 2012 Nov 20; 84(22):9655-62.
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Welch BD, Liu Y, Kors CA, Leser GP, Jardetzky TS, Lamb RA. Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):16672-7.
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Madian AG, Myracle AD, Diaz-Maldonado N, Rochelle NS, Janle EM, Regnier FE. Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins. Anal Chem. 2011 Dec 15; 83(24):9328-36.
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Gao Q, Madian AG, Liu X, Adamec J, Regnier FE. Coupling protein complex analysis to peptide based proteomics. J Chromatogr A. 2010 Dec 03; 1217(49):7661-8.
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Madian AG, Regnier FE. Profiling carbonylated proteins in human plasma. J Proteome Res. 2010 Mar 05; 9(3):1330-43.
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