"Trypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
| Descriptor ID |
D014357
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| MeSH Number(s) |
D08.811.277.656.300.760.895 D08.811.277.656.959.350.895
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Trypsin".
Below are MeSH descriptors whose meaning is more specific than "Trypsin".
This graph shows the total number of publications written about "Trypsin" by people in this website by year, and whether "Trypsin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 2 | 3 |
| 1995 | 1 | 5 | 6 |
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 2002 | 1 | 4 | 5 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trypsin" by people in Profiles.
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diDO-IPTL: A Peptide-Labeling Strategy for Precision Quantitative Proteomics. Anal Chem. 2017 11 07; 89(21):11498-11504.
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Enzymatically Modified Low-Density Lipoprotein Promotes Foam Cell Formation in Smooth Muscle Cells via Macropinocytosis and Enhances Receptor-Mediated Uptake of Oxidized Low-Density Lipoprotein. Arterioscler Thromb Vasc Biol. 2016 06; 36(6):1101-13.
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Differential expression of 26S proteasome subunits and functional activity during neonatal development. Biomolecules. 2014 Aug 29; 4(3):812-26.
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Low penetrance pancreatitis phenotype in a Venezuelan kindred with a PRSS1 R122H mutation. JOP. 2013 Mar 10; 14(2):187-9.
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Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.
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Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring. Anal Chem. 2012 Nov 20; 84(22):9655-62.
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Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):16672-7.
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Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins. Anal Chem. 2011 Dec 15; 83(24):9328-36.
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Coupling protein complex analysis to peptide based proteomics. J Chromatogr A. 2010 Dec 03; 1217(49):7661-8.
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Profiling carbonylated proteins in human plasma. J Proteome Res. 2010 Mar 05; 9(3):1330-43.