"Rad51 Recombinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Rec A recombinase found in eukaryotes. Rad51 is involved in DNA REPAIR of double-strand breaks.
| Descriptor ID |
D051135
|
| MeSH Number(s) |
D08.811.739.650.500 D12.776.260.695 D12.776.313.968
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rad51 Recombinase".
Below are MeSH descriptors whose meaning is more specific than "Rad51 Recombinase".
This graph shows the total number of publications written about "Rad51 Recombinase" by people in this website by year, and whether "Rad51 Recombinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 3 | 0 | 3 |
| 2012 | 4 | 0 | 4 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 2 | 4 |
| 2015 | 4 | 2 | 6 |
| 2016 | 3 | 0 | 3 |
| 2019 | 3 | 2 | 5 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Rad51 Recombinase" by people in Profiles.
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Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination. Nucleic Acids Res. 2021 12 16; 49(22):13135-13149.
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Neutrophils Alter DNA Repair Landscape to Impact Survival and Shape Distinct Therapeutic Phenotypes of Colorectal Cancer. Gastroenterology. 2021 07; 161(1):225-238.e15.
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Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer. Nat Commun. 2020 05 29; 11(1):2662.
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A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability. PLoS Genet. 2019 12; 15(12):e1008217.
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Non-enzymatic roles of human RAD51 at stalled replication forks. Nat Commun. 2019 09 27; 10(1):4410.
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Optimization of Drug Candidates That Inhibit the D-Loop Activity of RAD51. ChemMedChem. 2019 05 17; 14(10):1031-1040.
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RPA resolves conflicting activities of accessory proteins during reconstitution of Dmc1-mediated meiotic recombination. Nucleic Acids Res. 2019 01 25; 47(2):747-761.
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Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing. J Clin Invest. 2019 02 01; 129(2):712-726.
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Recent Developments Using Small Molecules to Target RAD51: How to Best Modulate RAD51 for Anticancer Therapy? ChemMedChem. 2016 11 21; 11(22):2468-2473.
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Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51. J Med Chem. 2016 05 26; 59(10):4511-25.