"SMARCB1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A component of the SWI-SNF CHROMATIN REMODELING complex that functions as a PROTEIN PHOSPHATASE 1 regulator and to stabilize CHROMATIN at PROMOTER REGIONS. It is important for regulating CELL PROLIFERATION and CELL DIFFERENTIATION. Mutations in the SMARCB1 gene are associated with malignant RHABDOID TUMORS.
| Descriptor ID |
D000071796
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| MeSH Number(s) |
D12.776.260.716 D12.776.660.235.650 D12.776.664.235.900 D12.776.930.809
|
| Concept/Terms |
SMARCB1 Protein- SMARCB1 Protein
- Integrase Interactor 1 Protein
- BAF47 Protein
- SNF5 Homolog Protein
- Swi-Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1
- Swi Snf Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1
- BRG1-Associated Factor 47 Protein
- BRG1 Associated Factor 47 Protein
|
Below are MeSH descriptors whose meaning is more general than "SMARCB1 Protein".
Below are MeSH descriptors whose meaning is more specific than "SMARCB1 Protein".
This graph shows the total number of publications written about "SMARCB1 Protein" by people in this website by year, and whether "SMARCB1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "SMARCB1 Protein" by people in Profiles.
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Evaluation of SWI/SNF Protein Expression by Immunohistochemistry in Ovarian Clear Cell Carcinoma. Int J Gynecol Pathol. 2021 Mar 01; 40(2):156-164.
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Primary epithelioid sarcoma of the kidney and adrenal gland: report of 2 cases with immunohistochemical and molecular cytogenetic studies. Hum Pathol. 2017 03; 61:158-163.
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Description of a new oncogenic mechanism for atypical teratoid rhabdoid tumors in patients with ring chromosome 22. Am J Med Genet A. 2017 Jan; 173(1):245-249.
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Epigenetic regulation of SMARCB1 By miR-206, -381 and -671-5p is evident in a variety of SMARCB1 immunonegative soft tissue sarcomas, while miR-765 appears specific for epithelioid sarcoma. A miRNA study of 223 soft tissue sarcomas. Genes Chromosomes Cancer. 2016 10; 55(10):786-802.
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SMARCB1 expression in epithelioid sarcoma is regulated by miR-206, miR-381, and miR-671-5p on Both mRNA and protein levels. Genes Chromosomes Cancer. 2014 Feb; 53(2):168-76.
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SMARCB1 protein and mRNA loss is not caused by promoter and histone hypermethylation in epithelioid sarcoma. Mod Pathol. 2013 Mar; 26(3):393-403.
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Renal medullary carcinoma: rhabdoid features and the absence of INI1 expression as markers of aggressive behavior. Mod Pathol. 2008 Jun; 21(6):647-52.
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Kaposi's sarcoma-associated herpesvirus K8 protein interacts with hSNF5. J Gen Virol. 2003 Mar; 84(Pt 3):665-676.