Interferon-Stimulated Gene Factor 3
"Interferon-Stimulated Gene Factor 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
| Descriptor ID |
D050832
|
| MeSH Number(s) |
D12.644.360.024.303 D12.776.157.057.061 D12.776.260.513 D12.776.476.024.386 D12.776.930.354
|
| Concept/Terms |
Interferon-Stimulated Gene Factor 3- Interferon-Stimulated Gene Factor 3
- Interferon Stimulated Gene Factor 3
- Transcription Factor ISGF3
- ISGF3, Transcription Factor
- ISGF3 Transcription Factor
- Transcription Factor, ISGF3
- IFN-Stimulated Gene Factor 3 Complex
- IFN Stimulated Gene Factor 3 Complex
- ISGF3 Factor
|
Below are MeSH descriptors whose meaning is more general than "Interferon-Stimulated Gene Factor 3".
Below are MeSH descriptors whose meaning is more specific than "Interferon-Stimulated Gene Factor 3".
This graph shows the total number of publications written about "Interferon-Stimulated Gene Factor 3" by people in this website by year, and whether "Interferon-Stimulated Gene Factor 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon-Stimulated Gene Factor 3" by people in Profiles.
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Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J Virol. 2004 Apr; 78(8):4185-96.
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Induction of endothelial-leukocyte interaction by interferon-gamma requires coactivation of nuclear factor-kappaB. Arterioscler Thromb Vasc Biol. 2001 Feb; 21(2):227-32.
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Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1. Genes Dev. 1996 Sep 15; 10(18):2335-47.