"Genes, src" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (src) originally isolated from the Rous sarcoma virus (RSV). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20.
Descriptor ID |
D016391
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MeSH Number(s) |
G05.360.340.024.340.375.500.791.570
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Concept/Terms |
src Oncogene- src Oncogene
- Oncogene, src
- Oncogenes, src
- src Oncogenes
- v-src Oncogenes
- Oncogene, v-src
- Oncogenes, v-src
- v src Oncogenes
- v-src Oncogene
- v-src Genes
- Gene, v-src
- Genes, v-src
- v src Genes
- v-src Gene
c-src Genes- c-src Genes
- Gene, c-src
- Genes, c-src
- c src Genes
- c-src Gene
- c-src Proto-Oncogenes
- Proto-Oncogene, c-src
- Proto-Oncogenes, c-src
- c src Proto Oncogenes
- c-src Proto-Oncogene
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Below are MeSH descriptors whose meaning is more general than "Genes, src".
Below are MeSH descriptors whose meaning is more specific than "Genes, src".
This graph shows the total number of publications written about "Genes, src" by people in this website by year, and whether "Genes, src" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1997 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, src" by people in Profiles.
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FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation. Dev Cell. 2005 Aug; 9(2):185-96.
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Role of focal adhesion proteins in signal transduction and oncogenesis. Crit Rev Oncog. 1997; 8(4):343-58.
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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL. J Biol Chem. 1995 Mar 10; 270(10):5039-47.
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Molecular genetics of myeloid leukemia: identification of the commonly deleted segment of chromosome 20. Blood. 1993 Dec 01; 82(11):3424-9.
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Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell. 1993 Jun 18; 73(6):1117-24.
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Tyrosine phosphorylation of a gap junction protein correlates with inhibition of cell-to-cell communication. Cell Growth Differ. 1990 Dec; 1(12):661-8.