Myeloid Differentiation Factor 88
"Myeloid Differentiation Factor 88" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
| Descriptor ID |
D053594
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| MeSH Number(s) |
D12.644.360.024.311 D12.776.157.057.074 D12.776.476.024.390
|
| Concept/Terms |
Myeloid Differentiation Factor 88- Myeloid Differentiation Factor 88
- Toll-Like Receptor Signal Adaptor Protein MyD88
- Toll Like Receptor Signal Adaptor Protein MyD88
- MyD88 Protein
- TLR Signal Adaptor Protein MyD88
|
Below are MeSH descriptors whose meaning is more general than "Myeloid Differentiation Factor 88".
Below are MeSH descriptors whose meaning is more specific than "Myeloid Differentiation Factor 88".
This graph shows the total number of publications written about "Myeloid Differentiation Factor 88" by people in this website by year, and whether "Myeloid Differentiation Factor 88" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 3 | 4 |
| 2009 | 4 | 3 | 7 |
| 2010 | 1 | 0 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 2 | 2 | 4 |
| 2014 | 0 | 6 | 6 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myeloid Differentiation Factor 88" by people in Profiles.
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The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model. PLoS Pathog. 2022 04; 18(4):e1010402.
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B cell superantigens in the human intestinal microbiota. Sci Transl Med. 2019 08 28; 11(507).
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MYD88 Mutations and Sensitivity to Ibrutinib Therapy. J Mol Diagn. 2018 03; 20(2):264-266.
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Effect of N-Acetylserotonin on TLR-4 and MyD88 Expression during Intestinal Ischemia-Reperfusion in a Rat Model. Eur J Pediatr Surg. 2019 Apr; 29(2):188-195.
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Bim suppresses the development of SLE by limiting myeloid inflammatory responses. J Exp Med. 2017 Dec 04; 214(12):3753-3773.
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Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens. Science. 2017 04 21; 356(6335):315-319.
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Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children. N Engl J Med. 2016 Aug 04; 375(5):411-421.
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Maternal and fetal roles in bacterially induced preterm labor in the mouse. Am J Obstet Gynecol. 2016 Mar; 214(3):386.e1-9.
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Microbiota regulates type 1 diabetes through Toll-like receptors. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):9973-7.
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Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes. Sci Signal. 2015 Jan 27; 8(361):ra10.