"14-3-3 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding proteins involved in important cellular processes including SIGNAL TRANSDUCTION; CELL CYCLE control; APOPTOSIS; and cellular stress responses. 14-3-3 proteins function by interacting with other signal-transducing proteins and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the proteins.
| Descriptor ID |
D048948
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| MeSH Number(s) |
D12.644.360.024.050 D12.776.157.057.002 D12.776.476.024.050
|
| Concept/Terms |
14-3-3 Proteins- 14-3-3 Proteins
- 14 3 3 Proteins
- 14-3-3 Protein
- 14 3 3 Protein
- Brain 14-3-3 Protein
- 14-3-3 Protein, Brain
- Brain 14 3 3 Protein
- Protein 14-3-3
14-3-3 Protein, tau Isoform- 14-3-3 Protein, tau Isoform
- 14 3 3 Protein, tau Isoform
- 14-3-3tau Protein
- 14 3 3tau Protein
- Protein, 14-3-3tau
- 14-3-3 tau Protein
- 14 3 3 tau Protein
14-3-3 Protein, zeta Isoform- 14-3-3 Protein, zeta Isoform
- 14 3 3 Protein, zeta Isoform
- 14-3-3zeta Protein
- 14 3 3zeta Protein
- 14-3-3 zeta Protein
- 14 3 3 zeta Protein
14-3-3 Protein, eta Isoform- 14-3-3 Protein, eta Isoform
- 14 3 3 Protein, eta Isoform
- 14-3-3eta Protein
- 14 3 3eta Protein
- 14-3-3 eta Protein
- 14 3 3 eta Protein
- eta Protein, 14-3-3
14-3-3 Protein, epsilon Isoform- 14-3-3 Protein, epsilon Isoform
- 14 3 3 Protein, epsilon Isoform
- 14-3-3 epsilon Protein
- 14 3 3 epsilon Protein
- 14-3-3epsilon Protein
- 14 3 3epsilon Protein
14-3-3 Protein, gamma Isoform- 14-3-3 Protein, gamma Isoform
- 14 3 3 Protein, gamma Isoform
- 14-3-3gamma Protein
- 14 3 3gamma Protein
- 14-3-3 gamma Protein
- 14 3 3 gamma Protein
14-3-3 Protein, beta Isoform- 14-3-3 Protein, beta Isoform
- 14 3 3 Protein, beta Isoform
- 14-3-3beta Protein
- 14 3 3beta Protein
- 14-3-3 beta Protein
- 14 3 3 beta Protein
|
Below are MeSH descriptors whose meaning is more general than "14-3-3 Proteins".
Below are MeSH descriptors whose meaning is more specific than "14-3-3 Proteins".
This graph shows the total number of publications written about "14-3-3 Proteins" by people in this website by year, and whether "14-3-3 Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "14-3-3 Proteins" by people in Profiles.
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Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity. Cell Host Microbe. 2019 10 09; 26(4):493-503.e6.
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Enhancement of mitochondrial biogenesis and paradoxical inhibition of lactate dehydrogenase mediated by 14-3-3? in oncocytomas. J Pathol. 2018 07; 245(3):361-372.
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A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity. Nat Immunol. 2016 May; 17(5):523-30.
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The duplication 17p13.3 phenotype: analysis of 21 families delineates developmental, behavioral and brain abnormalities, and rare variant phenotypes. Am J Med Genet A. 2013 Aug; 161A(8):1833-52.
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Family-based association of YWHAH in psychotic bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 05; 150B(7):977-83.
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14-3-3 zeta protein secreted by tumor associated monocytes/macrophages from ascites of epithelial ovarian cancer patients. Cancer Immunol Immunother. 2009 Feb; 58(2):247-58.
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How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol. 2007 Nov; 14(11):1025-1040.
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14-3-3 proteins are involved in the regulation of mammalian cell proliferation. Amino Acids. 2006 Feb; 30(1):105-9.
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14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul; 34(3):274-85.
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Lissencephaly and the molecular basis of neuronal migration. Hum Mol Genet. 2003 Apr 01; 12 Spec No 1:R89-96.