AMP-Activated Protein Kinases
"AMP-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.
Descriptor ID |
D055372
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MeSH Number(s) |
D08.811.913.696.620.682.700.085 D12.644.360.062 D12.776.476.062
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Concept/Terms |
AMP-Activated Protein Kinases- AMP-Activated Protein Kinases
- AMP Activated Protein Kinases
- AMP-Activated Protein Kinase
- AMP Activated Protein Kinase
- 5'-AMP-Activated Protein Kinase
- 5' AMP Activated Protein Kinase
- AMP-Activated Kinase
- AMP Activated Kinase
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Below are MeSH descriptors whose meaning is more general than "AMP-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "AMP-Activated Protein Kinases".
This graph shows the total number of publications written about "AMP-Activated Protein Kinases" by people in this website by year, and whether "AMP-Activated Protein Kinases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 2 | 2 | 2005 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2008 | 1 | 0 | 1 | 2009 | 3 | 0 | 3 | 2010 | 2 | 0 | 2 | 2011 | 1 | 1 | 2 | 2012 | 1 | 3 | 4 | 2013 | 0 | 3 | 3 | 2014 | 2 | 1 | 3 | 2015 | 2 | 5 | 7 | 2016 | 2 | 0 | 2 | 2017 | 3 | 1 | 4 | 2018 | 1 | 1 | 2 | 2019 | 3 | 2 | 5 | 2020 | 1 | 1 | 2 | 2021 | 5 | 0 | 5 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "AMP-Activated Protein Kinases" by people in Profiles.
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Tatsumi Y, Kato A, Niimi N, Yako H, Himeno T, Kondo M, Tsunekawa S, Kato Y, Kamiya H, Nakamura J, Higai K, Sango K, Kato K. Docosahexaenoic Acid Suppresses Oxidative Stress-Induced Autophagy and Cell Death via the AMPK-Dependent Signaling Pathway in Immortalized Fischer Rat Schwann Cells 1. Int J Mol Sci. 2022 Apr 15; 23(8).
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Ahmad I, Molyvdas A, Jian MY, Zhou T, Traylor AM, Cui H, Liu G, Song W, Agarwal A, Jilling T, Aggarwal S, Matalon S. AICAR decreases acute lung injury by phosphorylating AMPK and upregulating heme oxygenase-1. Eur Respir J. 2021 12; 58(6).
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Lee Y, Lee J, Lee MS, Chang E, Kim Y. Chrysanthemum morifolium Flower Extract Ameliorates Obesity-Induced Inflammation and Increases the Muscle Mitochondria Content and AMPK/SIRT1 Activities in Obese Rats. Nutrients. 2021 Oct 19; 13(10).
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Yan Y, Mukherjee S, Harikumar KG, Strutzenberg TS, Zhou XE, Suino-Powell K, Xu TH, Sheldon RD, Lamp J, Brunzelle JS, Radziwon K, Ellis A, Novick SJ, Vega IE, Jones RG, Miller LJ, Xu HE, Griffin PR, Kossiakoff AA, Melcher K. Structure of an AMPK complex in an inactive, ATP-bound state. Science. 2021 07 23; 373(6553):413-419.
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Bhutta MS, Gallo ES, Borenstein R. Multifaceted Role of AMPK in Viral Infections. Cells. 2021 05 06; 10(5).
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Marinaccio C, Suraneni P, Celik H, Volk A, Wen QJ, Ling T, Bulic M, Lasho T, Koche RP, Famulare CA, Farnoud N, Stein B, Schieber M, Gurbuxani S, Root DE, Younger ST, Hoffman R, Gangat N, Ntziachristos P, Chandel NS, Levine RL, Rampal RK, Challen GA, Tefferi A, Crispino JD. LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms. Cancer Discov. 2021 06; 11(6):1398-1410.
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Prisco SZ, Rose L, Potus F, Tian L, Wu D, Hartweck L, Al-Qazazi R, Neuber-Hess M, Eklund M, Hsu S, Thenappan T, Archer SL, Prins KW. Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. Int J Mol Sci. 2020 Oct 01; 21(19).
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Ozcan C, Dixit G, Li Z. Activation of AMP-Activated Protein Kinases Prevents Atrial Fibrillation. J Cardiovasc Transl Res. 2021 06; 14(3):492-502.
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Chang E, Kim Y. Vitamin D Ameliorates Fat Accumulation with AMPK/SIRT1 Activity in C2C12 Skeletal Muscle Cells. Nutrients. 2019 Nov 17; 11(11).
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Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, Wang M, Wu S, Dai Q, Vu H, Zacharias L, DeBerardinis R, Lim E, Metallo C, Boggon TJ, Lonial S, Lin R, Mao H, Pan Y, Shan C, Chen J. ?-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell. 2019 12 19; 76(6):857-871.e9.
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