 AMP-Activated Protein Kinases
"AMP-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.
| Descriptor ID |
D055372
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| MeSH Number(s) |
D08.811.913.696.620.682.700.085 D12.644.360.062 D12.776.476.062
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| Concept/Terms |
AMP-Activated Protein Kinases- AMP-Activated Protein Kinases
- AMP Activated Protein Kinases
- AMP-Activated Protein Kinase
- AMP Activated Protein Kinase
- 5'-AMP-Activated Protein Kinase
- 5' AMP Activated Protein Kinase
- AMP-Activated Kinase
- AMP Activated Kinase
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Below are MeSH descriptors whose meaning is more general than "AMP-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "AMP-Activated Protein Kinases".
This graph shows the total number of publications written about "AMP-Activated Protein Kinases" by people in this website by year, and whether "AMP-Activated Protein Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2003 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2008 | 2 | 0 | 2 | | 2009 | 3 | 0 | 3 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 3 | 5 | | 2016 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "AMP-Activated Protein Kinases" by people in Profiles.
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Jang S, Gornicki P, Marjanovic J, Bass E, P Iurcotta T, Rodriguez P, Austin J, Haselkorn R. Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor. FEBS Lett. 2018 06; 592(12):2048-2058.
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Liu W, Jiang Y, Sun J, Geng S, Pan Z, Prinz RA, Wang C, Sun J, Jiao X, Xu X. Activation of TGF-ß-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy. Cell Death Dis. 2018 05 01; 9(5):570.
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Wang S, Huo D, Ogundiran TO, Ojengbede O, Zheng W, Nathanson KL, Nemesure B, Ambs S, Olopade OI, Zheng Y. Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium. Carcinogenesis. 2017 08 01; 38(8):789-796.
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Chang E, Kim Y. Vitamin D Insufficiency Exacerbates Adipose Tissue Macrophage Infiltration and Decreases AMPK/SIRT1 Activity in Obese Rats. Nutrients. 2017 Mar 29; 9(4).
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Cho KJ, Casteel DE, Prakash P, Tan L, van der Hoeven D, Salim AA, Kim C, Capon RJ, Lacey E, Cunha SR, Gorfe AA, Hancock JF. AMPK and Endothelial Nitric Oxide Synthase Signaling Regulates K-Ras Plasma Membrane Interactions via Cyclic GMP-Dependent Protein Kinase 2. Mol Cell Biol. 2016 12 15; 36(24):3086-3099.
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Shahin MH, Gong Y, McDonough CW, Rotroff DM, Beitelshees AL, Garrett TJ, Gums JG, Motsinger-Reif A, Chapman AB, Turner ST, Boerwinkle E, Frye RF, Fiehn O, Cooper-DeHoff RM, Kaddurah-Daouk R, Johnson JA. A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. Hypertension. 2016 09; 68(3):621-9.
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Gozal D. The Energy Crisis Revisited: AMP-activated Protein Kinase and the Mammalian Hypoxic Ventilatory Response. Am J Respir Crit Care Med. 2016 05 01; 193(9):945-6.
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Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov; 17(11):1484-96.
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Seo S, Lee MS, Chang E, Shin Y, Oh S, Kim IH, Kim Y. Rutin Increases Muscle Mitochondrial Biogenesis with AMPK Activation in High-Fat Diet-Induced Obese Rats. Nutrients. 2015 Sep 22; 7(9):8152-69.
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Swisa A, Granot Z, Tamarina N, Sayers S, Bardeesy N, Philipson L, Hodson DJ, Wikstrom JD, Rutter GA, Leibowitz G, Glaser B, Dor Y. Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects. J Biol Chem. 2015 Aug 21; 290(34):20934-46.
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