Loading...
The University of Chicago Header Logo
Keywords
Last Name
Institution

NANDURI R. PRABHAKAR

TitleProfessor
InstitutionUniversity of Chicago
DepartmentMedicine-Emergency Medicine
AddressChicago IL 60637
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Peng YJ, Makarenko VV, Gridina A, Chupikova I, Zhang X, Kumar GK, Fox AP, Prabhakar NR. H2S mediates carotid body response to hypoxia but not anoxia. Respir Physiol Neurobiol. 2019 Jan; 259:75-85. PMID: 30086385.
      View in: PubMed
    2. Prabhakar NR, Peng YJ, Yuan G, Nanduri J. Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia. Cell Tissue Res. 2018 05; 372(2):427-431. PMID: 29470646.
      View in: PubMed
    3. Semenza GL, Prabhakar NR. The role of hypoxia-inducible factors in carotid body (patho) physiology. J Physiol. 2018 Aug; 596(15):2977-2983. PMID: 29359806.
      View in: PubMed
    4. Nanduri J, Peng YJ, Wang N, Khan SA, Semenza GL, Prabhakar NR. DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity. J Physiol. 2018 Aug; 596(15):3087-3100. PMID: 29148180.
      View in: PubMed
    5. Peng YJ, Prabhakar NR. Measurement of Sensory Nerve Activity from the Carotid Body. Methods Mol Biol. 2018; 1742:115-124. PMID: 29330795.
      View in: PubMed
    6. Nanduri J, Prabhakar NR. Immunohistochemistry of the Carotid Body. Methods Mol Biol. 2018; 1742:155-166. PMID: 29330798.
      View in: PubMed
    7. Peng YJ, Zhang X, Nanduri J, Prabhakar NR. Therapeutic Targeting of the Carotid Body for Treating Sleep Apnea in a Pre-clinical Mouse Model. Adv Exp Med Biol. 2018; 1071:109-114. PMID: 30357741.
      View in: PubMed
    8. Nanduri J, Semenza GL, Prabhakar NR. Epigenetic changes by DNA methylation in chronic and intermittent hypoxia. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 01; 313(6):L1096-L1100. PMID: 28839104.
      View in: PubMed
    9. Wu D, Huang RT, Hamanaka RB, Krause M, Oh MJ, Kuo CH, Nigdelioglu R, Meliton AY, Witt L, Dai G, Civelek M, Prabhakar NR, Fang Y, Mutlu GM. HIF-1a is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium. Elife. 2017 May 30; 6. PMID: 28556776.
      View in: PubMed
    10. Samanta D, Prabhakar NR, Semenza GL. Systems biology of oxygen homeostasis. Wiley Interdiscip Rev Syst Biol Med. 2017 Jul; 9(4). PMID: 28221004.
      View in: PubMed
    11. Peng YJ, Zhang X, Gridina A, Chupikova I, McCormick DL, Thomas RJ, Scammell TE, Kim G, Vasavda C, Nanduri J, Kumar GK, Semenza GL, Snyder SH, Prabhakar NR. Complementary roles of gasotransmitters CO and H2S in sleep apnea. Proc Natl Acad Sci U S A. 2017 Feb 07; 114(6):1413-1418. PMID: 28115703.
      View in: PubMed
    12. Prabhakar NR, Peng YJ. Oxygen Sensing by the Carotid Body: Past and Present. Adv Exp Med Biol. 2017; 977:3-8. PMID: 28685420.
      View in: PubMed
    13. Applebaum MA, Jha AR, Kao C, Hernandez KM, DeWane G, Salwen HR, Chlenski A, Dobratic M, Mariani CJ, Godley LA, Prabhakar N, White K, Stranger BE, Cohn SL. Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients. Oncotarget. 2016 Nov 22; 7(47):76816-76826. PMID: 27765905.
      View in: PubMed
    14. Nanduri J, Peng YJ, Wang N, Khan SA, Semenza GL, Kumar GK, Prabhakar NR. Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia. J Physiol. 2017 Jan 01; 595(1):63-77. PMID: 27506145.
      View in: PubMed
    15. Yuan G, Peng YJ, Khan SA, Nanduri J, Singh A, Vasavda C, Semenza GL, Kumar GK, Snyder SH, Prabhakar NR. H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea. Sci Signal. 2016 Aug 16; 9(441):ra80. PMID: 27531649.
      View in: PubMed
    16. Prabhakar NR. Carotid body chemoreflex: a driver of autonomic abnormalities in sleep apnoea. Exp Physiol. 2016 Aug 01; 101(8):975-85. PMID: 27474260.
      View in: PubMed
    17. Garcia AJ, Zanella S, Dashevskiy T, Khan SA, Khuu MA, Prabhakar NR, Ramirez JM. Chronic Intermittent Hypoxia Alters Local Respiratory Circuit Function at the Level of the preBötzinger Complex. Front Neurosci. 2016; 10:4. PMID: 26869872.
      View in: PubMed
    18. Wang N, Kang HS, Ahmmed G, Khan SA, Makarenko VV, Prabhakar NR, Nanduri J. Calpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia. Am J Physiol Cell Physiol. 2016 Mar 01; 310(5):C329-36. PMID: 26659724.
      View in: PubMed
    19. Makarenko VV, Ahmmed GU, Peng YJ, Khan SA, Nanduri J, Kumar GK, Fox AP, Prabhakar NR. CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia. J Neurophysiol. 2016 Jan 01; 115(1):345-54. PMID: 26561606.
      View in: PubMed
    20. Prabhakar NR, Semenza GL. Oxygen Sensing and Homeostasis. Physiology (Bethesda). 2015 Sep; 30(5):340-8. PMID: 26328879.
      View in: PubMed
    21. Prabhakar NR, Semenza GL. Regulation of carotid body oxygen sensing by hypoxia-inducible factors. Pflugers Arch. 2016 Jan; 468(1):71-5. PMID: 26265380.
      View in: PubMed
    22. Semenza GL, Prabhakar NR. Neural regulation of hypoxia-inducible factors and redox state drives the pathogenesis of hypertension in a rodent model of sleep apnea. J Appl Physiol (1985). 2015 Nov 15; 119(10):1152-6. PMID: 25953833.
      View in: PubMed
    23. Yuan G, Vasavda C, Peng YJ, Makarenko VV, Raghuraman G, Nanduri J, Gadalla MM, Semenza GL, Kumar GK, Snyder SH, Prabhakar NR. Protein kinase G-regulated production of H2S governs oxygen sensing. Sci Signal. 2015 Apr 21; 8(373):ra37. PMID: 25900831.
      View in: PubMed
    24. Prabhakar NR, Peng YJ, Kumar GK, Nanduri J. Peripheral chemoreception and arterial pressure responses to intermittent hypoxia. Compr Physiol. 2015 Apr; 5(2):561-77. PMID: 25880505.
      View in: PubMed
    25. Nanduri J, Peng YJ, Yuan G, Kumar GK, Prabhakar NR. Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome. J Mol Med (Berl). 2015 May; 93(5):473-80. PMID: 25772710.
      View in: PubMed
    26. Nanduri J, Vaddi DR, Khan SA, Wang N, Makarenko V, Semenza GL, Prabhakar NR. HIF-1a activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase. PLoS One. 2015; 10(3):e0119762. PMID: 25751622.
      View in: PubMed
    27. Kumar GK, Nanduri J, Peng YJ, Prabhakar NR. Neuromolecular mechanisms mediating the effects of chronic intermittent hypoxia on adrenal medulla. Respir Physiol Neurobiol. 2015 Apr; 209:115-9. PMID: 25583660.
      View in: PubMed
    28. Nanduri J, Prabhakar NR. Epigenetic Regulation of Carotid Body Oxygen Sensing: Clinical Implications. Adv Exp Med Biol. 2015; 860:1-8. PMID: 26303461.
      View in: PubMed
    29. Kumar GK, Peng YJ, Nanduri J, Prabhakar NR. Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla. Adv Exp Med Biol. 2015; 860:195-9. PMID: 26303481.
      View in: PubMed
    30. Peers C, Kumar P, Wyatt C, Gauda E, Nurse C, Prabhakar N. This volume of Advances in Experimental Medicine and Biology holds the proceedings of the XVIIIth meeting. Introduction. Adv Exp Med Biol. 2015; 860:v-vi. PMID: 26605404.
      View in: PubMed
    31. Makarenko VV, Peng YJ, Yuan G, Fox AP, Kumar GK, Nanduri J, Prabhakar NR. CaV3.2 T-type Ca²? channels in H2S-mediated hypoxic response of the carotid body. Am J Physiol Cell Physiol. 2015 Jan 15; 308(2):C146-54. PMID: 25377087.
      View in: PubMed
    32. Peng YJ, Yuan G, Khan S, Nanduri J, Makarenko VV, Reddy VD, Vasavda C, Kumar GK, Semenza GL, Prabhakar NR. Regulation of hypoxia-inducible factor-a isoforms and redox state by carotid body neural activity in rats. J Physiol. 2014 Sep 01; 592(17):3841-58. PMID: 24973414.
      View in: PubMed
    33. Kåhlin J, Mkrtchian S, Ebberyd A, Hammarstedt-Nordenvall L, Nordlander B, Yoshitake T, Kehr J, Prabhakar N, Poellinger L, Fagerlund MJ, Eriksson LI. The human carotid body releases acetylcholine, ATP and cytokines during hypoxia. Exp Physiol. 2014 Aug; 99(8):1089-98. PMID: 24887113.
      View in: PubMed
    34. Mariani CJ, Vasanthakumar A, Madzo J, Yesilkanal A, Bhagat T, Yu Y, Bhattacharyya S, Wenger RH, Cohn SL, Nanduri J, Verma A, Prabhakar NR, Godley LA. TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma. Cell Rep. 2014 Jun 12; 7(5):1343-52. PMID: 24835990.
      View in: PubMed
    35. Limberg JK, Curry TB, Prabhakar NR, Joyner MJ. Is insulin the new intermittent hypoxia? Med Hypotheses. 2014 Jun; 82(6):730-5. PMID: 24690299.
      View in: PubMed
    36. Takano N, Peng YJ, Kumar GK, Luo W, Hu H, Shimoda LA, Suematsu M, Prabhakar NR, Semenza GL. Hypoxia-inducible factors regulate human and rat cystathionine ß-synthase gene expression. Biochem J. 2014 Mar 01; 458(2):203-11. PMID: 24328859.
      View in: PubMed
    37. Makarenko VV, Usatyuk PV, Yuan G, Lee MM, Nanduri J, Natarajan V, Kumar GK, Prabhakar NR. Intermittent hypoxia-induced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation. Am J Physiol Cell Physiol. 2014 Apr 15; 306(8):C745-52. PMID: 24477234.
      View in: PubMed
    38. Peng YJ, Makarenko VV, Nanduri J, Vasavda C, Raghuraman G, Yuan G, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NR. Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1174-9. PMID: 24395806.
      View in: PubMed
    39. Prabhakar NR, Peers C. Gasotransmitter regulation of ion channels: a key step in O2 sensing by the carotid body. Physiology (Bethesda). 2014 Jan; 29(1):49-57. PMID: 24382871.
      View in: PubMed
    40. Nanduri J, Vaddi DR, Khan SA, Wang N, Makerenko V, Prabhakar NR. Xanthine oxidase mediates hypoxia-inducible factor-2a degradation by intermittent hypoxia. PLoS One. 2013; 8(10):e75838. PMID: 24124516.
      View in: PubMed
    41. Peng YJ, Nanduri J, Raghuraman G, Wang N, Kumar GK, Prabhakar NR. Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia. Exp Physiol. 2013 Nov; 98(11):1620-30. PMID: 23913764.
      View in: PubMed
    42. Ramirez JM, Garcia AJ, Anderson TM, Koschnitzky JE, Peng YJ, Kumar GK, Prabhakar NR. Central and peripheral factors contributing to obstructive sleep apneas. Respir Physiol Neurobiol. 2013 Nov 01; 189(2):344-53. PMID: 23770311.
      View in: PubMed
    43. Wang N, Khan SA, Prabhakar NR, Nanduri J. Impairment of pancreatic ß-cell function by chronic intermittent hypoxia. Exp Physiol. 2013 Sep; 98(9):1376-85. PMID: 23709585.
      View in: PubMed
    44. Yuan G, Peng YJ, Reddy VD, Makarenko VV, Nanduri J, Khan SA, Garcia JA, Kumar GK, Semenza GL, Prabhakar NR. Mutual antagonism between hypoxia-inducible factors 1a and 2a regulates oxygen sensing and cardio-respiratory homeostasis. Proc Natl Acad Sci U S A. 2013 May 07; 110(19):E1788-96. PMID: 23610397.
      View in: PubMed
    45. Prabhakar NR. Sensing hypoxia: physiology, genetics and epigenetics. J Physiol. 2013 May 01; 591(9):2245-57. PMID: 23459758.
      View in: PubMed
    46. Nanduri J, Prabhakar NR. Developmental programming of O(2) sensing by neonatal intermittent hypoxia via epigenetic mechanisms. Respir Physiol Neurobiol. 2013 Jan 01; 185(1):105-9. PMID: 22846496.
      View in: PubMed
    47. Prabhakar NR, Semenza GL. Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2. Physiol Rev. 2012 Jul; 92(3):967-1003. PMID: 22811423.
      View in: PubMed
    48. Makarenko VV, Nanduri J, Raghuraman G, Fox AP, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NR. Endogenous H2S is required for hypoxic sensing by carotid body glomus cells. Am J Physiol Cell Physiol. 2012 Nov 01; 303(9):C916-23. PMID: 22744006.
      View in: PubMed
    49. Prabhakar NR, Kumar GK, Peng YJ. Sympatho-adrenal activation by chronic intermittent hypoxia. J Appl Physiol (1985). 2012 Oct 15; 113(8):1304-10. PMID: 22723632.
      View in: PubMed
    50. Prabhakar NR. Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body. Respir Physiol Neurobiol. 2012 Nov 15; 184(2):165-9. PMID: 22664830.
      View in: PubMed
    51. Rajamohan SB, Raghuraman G, Prabhakar NR, Kumar GK. NADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cells. Antioxid Redox Signal. 2012 Aug 01; 17(3):445-59. PMID: 22214405.
      View in: PubMed
    52. Semenza GL, Prabhakar NR. Gas biology: small molecular medicine. J Mol Med (Berl). 2012 Mar; 90(3):213-5. PMID: 22349395.
      View in: PubMed
    53. Prabhakar NR, Semenza GL. Gaseous messengers in oxygen sensing. J Mol Med (Berl). 2012 Mar; 90(3):265-72. PMID: 22349394.
      View in: PubMed
    54. Nanduri J, Makarenko V, Reddy VD, Yuan G, Pawar A, Wang N, Khan SA, Zhang X, Kinsman B, Peng YJ, Kumar GK, Fox AP, Godley LA, Semenza GL, Prabhakar NR. Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2515-20. PMID: 22232674.
      View in: PubMed
    55. Prabhakar NR. Hydrogen sulfide (H(2)S): a physiologic mediator of carotid body response to hypoxia. Adv Exp Med Biol. 2012; 758:109-13. PMID: 23080150.
      View in: PubMed
    56. Raghuraman G, Prabhakar NR, Kumar GK. Differential regulation of tyrosine hydroxylase by continuous and intermittent hypoxia. Adv Exp Med Biol. 2012; 758:381-5. PMID: 23080186.
      View in: PubMed
    57. Kumar P, Prabhakar NR. Peripheral chemoreceptors: function and plasticity of the carotid body. Compr Physiol. 2012 Jan; 2(1):141-219. PMID: 23728973.
      View in: PubMed
    58. Semenza GL, Prabhakar NR. The role of hypoxia-inducible factors in oxygen sensing by the carotid body. Adv Exp Med Biol. 2012; 758:1-5. PMID: 23080136.
      View in: PubMed
    59. Prabhakar NR. Institute for integrative physiology: resurrection of physiology at the University of Chicago. Physiologist. 2011 Dec; 54(6):235-6. PMID: 22256730.
      View in: PubMed
    60. Wang T, Lang GD, Moreno-Vinasco L, Huang Y, Goonewardena SN, Peng YJ, Svensson EC, Natarajan V, Lang RM, Linares JD, Breysse PN, Geyh AS, Samet JM, Lussier YA, Dudley S, Prabhakar NR, Garcia JG. Particulate matter induces cardiac arrhythmias via dysregulation of carotid body sensitivity and cardiac sodium channels. Am J Respir Cell Mol Biol. 2012 Apr; 46(4):524-31. PMID: 22108299.
      View in: PubMed
    61. Yuan G, Khan SA, Luo W, Nanduri J, Semenza GL, Prabhakar NR. Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia. J Cell Physiol. 2011 Nov; 226(11):2925-33. PMID: 21302291.
      View in: PubMed
    62. Peng YJ, Nanduri J, Zhang X, Wang N, Raghuraman G, Seagard J, Kumar GK, Prabhakar NR. Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia. J Appl Physiol (1985). 2012 Jan; 112(1):187-96. PMID: 22016368.
      View in: PubMed
    63. Garcia AJ, Khan SA, Kumar GK, Prabhakar NR, Ramirez JM. Hydrogen peroxide differentially affects activity in the pre-Bötzinger complex and hippocampus. J Neurophysiol. 2011 Dec; 106(6):3045-55. PMID: 21849609.
      View in: PubMed
    64. Peng YJ, Raghuraman G, Khan SA, Kumar GK, Prabhakar NR. Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase. J Appl Physiol (1985). 2011 Oct; 111(4):964-70. PMID: 21636565.
      View in: PubMed
    65. Prabhakar NR. Sensory plasticity of the carotid body: role of reactive oxygen species and physiological significance. Respir Physiol Neurobiol. 2011 Sep 30; 178(3):375-80. PMID: 21621009.
      View in: PubMed
    66. Raghuraman G, Kalari A, Dhingra R, Prabhakar NR, Kumar GK. Enhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processing. Antioxid Redox Signal. 2011 Apr 01; 14(7):1179-90. PMID: 20836657.
      View in: PubMed
    67. Peng YJ, Nanduri J, Khan SA, Yuan G, Wang N, Kinsman B, Vaddi DR, Kumar GK, Garcia JA, Semenza GL, Prabhakar NR. Hypoxia-inducible factor 2a (HIF-2a) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):3065-70. PMID: 21288809.
      View in: PubMed
    68. Raghuraman G, Prabhakar NR, Kumar GK. Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling. J Neurochem. 2010 Dec; 115(6):1568-78. PMID: 20969567.
      View in: PubMed
    69. Khan SA, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR. NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats. Antioxid Redox Signal. 2011 Feb 15; 14(4):533-42. PMID: 20618070.
      View in: PubMed
    70. Prabhakar NR, Kumar GK, Nanduri J. Intermittent hypoxia augments acute hypoxic sensing via HIF-mediated ROS. Respir Physiol Neurobiol. 2010 Dec 31; 174(3):230-4. PMID: 20804864.
      View in: PubMed
    71. Prabhakar NR, Kumar GK. Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia. Respir Physiol Neurobiol. 2010 Nov 30; 174(1-2):156-61. PMID: 20804865.
      View in: PubMed
    72. Prabhakar NR. Redox Pioneer: Professor Gregg L. Semenza. Antioxid Redox Signal. 2010 Aug 15; 13(4):559-64. PMID: 20214500.
      View in: PubMed
    73. Souvannakitti D, Nanduri J, Yuan G, Kumar GK, Fox AP, Prabhakar NR. NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells. J Neurosci. 2010 Aug 11; 30(32):10763-72. PMID: 20705601.
      View in: PubMed
    74. Souvannakitti D, Kuri B, Yuan G, Pawar A, Kumar GK, Smith C, Fox AP, Prabhakar NR. Neonatal intermittent hypoxia impairs neuronal nicotinic receptor expression and function in adrenal chromaffin cells. Am J Physiol Cell Physiol. 2010 Aug; 299(2):C381-8. PMID: 20664070.
      View in: PubMed
    75. Peng YJ, Nanduri J, Raghuraman G, Souvannakitti D, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NR. H2S mediates O2 sensing in the carotid body. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10719-24. PMID: 20556885.
      View in: PubMed
    76. Prabhakar NR, Kumar GK, Nanduri J. Intermittent hypoxia-mediated plasticity of acute O2 sensing requires altered red-ox regulation by HIF-1 and HIF-2. Ann N Y Acad Sci. 2009 Oct; 1177:162-8. PMID: 19845618.
      View in: PubMed
    77. Nanduri J, Bergson P, Wang N, Ficker E, Prabhakar NR. Hypoxia inhibits maturation and trafficking of hERG K(+) channel protein: Role of Hsp90 and ROS. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):212-6. PMID: 19654002.
      View in: PubMed
    78. Raghuraman G, Rai V, Peng YJ, Prabhakar NR, Kumar GK. Pattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinases. Antioxid Redox Signal. 2009 Aug; 11(8):1777-89. PMID: 19335094.
      View in: PubMed
    79. Braga VA, Prabhakar NR. Refinement of telemetry for measuring blood pressure in conscious rats. J Am Assoc Lab Anim Sci. 2009 May; 48(3):268-71. PMID: 19476715.
      View in: PubMed
    80. Peng YJ, Nanduri J, Yuan G, Wang N, Deneris E, Pendyala S, Natarajan V, Kumar GK, Prabhakar NR. NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia. J Neurosci. 2009 Apr 15; 29(15):4903-10. PMID: 19369559.
      View in: PubMed
    81. Souvannakitti D, Kumar GK, Fox A, Prabhakar NR. Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells. J Neurophysiol. 2009 Jun; 101(6):2837-46. PMID: 19339466.
      View in: PubMed
    82. Castro M, Ramirez MI, Gern JE, Cutting G, Redding G, Hagood JS, Whitsett J, Abman S, Raj JU, Barst R, Kato GJ, Gozal D, Haddad GG, Prabhakar NR, Gauda E, Martinez FD, Tepper R, Wood RE, Accurso F, Teague WG, Venegas J, Cole FS, Wright RJ. Strategic plan for pediatric respiratory diseases research: an NHLBI working group report. Proc Am Thorac Soc. 2009 Jan 15; 6(1):1-10. PMID: 19131525.
      View in: PubMed
    83. Nanduri J, Wang N, Yuan G, Khan SA, Souvannakitti D, Peng YJ, Kumar GK, Garcia JA, Prabhakar NR. Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities. Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4):1199-204. PMID: 19147445.
      View in: PubMed
    84. Prabhakar NR, Peng YJ, Kumar GK, Nanduri J, Di Giulio C, Lahiri S. Long-term regulation of carotid body function: acclimatization and adaptation--invited article. Adv Exp Med Biol. 2009; 648:307-17. PMID: 19536494.
      View in: PubMed
    85. Souvannakitti D, Kumar GK, Fox A, Prabhakar NR. Contrasting effects of intermittent and continuous hypoxia on low O(2) evoked catecholamine secretion from neonatal rat chromaffin cells. Adv Exp Med Biol. 2009; 648:345-9. PMID: 19536498.
      View in: PubMed
    86. Abman S, Jobe A, Chernick V, Blaisdell C, Castro M, Ramirez MI, Gern JE, Cutting G, Redding G, Hagood JS, Whitsett J, Abman S, Raj JU, Barst R, Kato GJ, Gozal D, Haddad GG, Prabhakar NR, Gauda E, Martinez FD, Tepper R, Wood RE, Accurso F, Teague WG, Venegas J, Cole FS, Wright RJ, Gail D, Hamvas A, Kercsmar C, Kiley J, Weinmann G. Strategic plan for pediatric respiratory diseases research: an NHLBI working group report. Pediatr Pulmonol. 2009 Jan; 44(1):2-13. PMID: 19086051.
      View in: PubMed
    87. Pawar A, Nanduri J, Yuan G, Khan SA, Wang N, Kumar GK, Prabhakar NR. Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol. 2009 Mar; 296(3):R735-42. PMID: 19109370.
      View in: PubMed
    88. Nanduri J, Yuan G, Kumar GK, Semenza GL, Prabhakar NR. Transcriptional responses to intermittent hypoxia. Respir Physiol Neurobiol. 2008 Dec 10; 164(1-2):277-81. PMID: 18692603.
      View in: PubMed
    89. Kumar GK, Prabhakar NR. Post-translational modification of proteins during intermittent hypoxia. Respir Physiol Neurobiol. 2008 Dec 10; 164(1-2):272-6. PMID: 18602876.
      View in: PubMed
    90. Yuan G, Nanduri J, Khan S, Semenza GL, Prabhakar NR. Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR. J Cell Physiol. 2008 Dec; 217(3):674-85. PMID: 18651560.
      View in: PubMed
    91. Marek W, Muckenhoff K, Prabhakar NR. Significance of pulmonary vagal afferents for respiratory muscle activity in the cat. J Physiol Pharmacol. 2008 Dec; 59 Suppl 6:407-20. PMID: 19218665.
      View in: PubMed
    92. Sharma SD, Raghuraman G, Lee MS, Prabhakar NR, Kumar GK. Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing. J Appl Physiol (1985). 2009 Jan; 106(1):12-9. PMID: 18818385.
      View in: PubMed
    93. Nanduri J, Wang N, Bergson P, Yuan G, Ficker E, Prabhakar NR. Mitochondrial reactive oxygen species mediate hypoxic down-regulation of hERG channel protein. Biochem Biophys Res Commun. 2008 Aug 22; 373(2):309-14. PMID: 18570888.
      View in: PubMed
    94. Pawar A, Peng YJ, Jacono FJ, Prabhakar NR. Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia. J Appl Physiol (1985). 2008 May; 104(5):1287-94. PMID: 18187605.
      View in: PubMed
    95. Akada S, Fagerlund MJ, Lindahl SG, Sakamoto A, Prabhakar NR, Eriksson LI. Pronounced depression by propofol on carotid body response to CO2 and K+-induced carotid body activation. Respir Physiol Neurobiol. 2008 Feb 29; 160(3):284-8. PMID: 18054527.
      View in: PubMed
    96. Prabhakar NR, Kumar GK, Nanduri J, Semenza GL. ROS signaling in systemic and cellular responses to chronic intermittent hypoxia. Antioxid Redox Signal. 2007 Sep; 9(9):1397-403. PMID: 17627465.
      View in: PubMed
    97. Semenza GL, Prabhakar NR. HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia. Antioxid Redox Signal. 2007 Sep; 9(9):1391-6. PMID: 17627473.
      View in: PubMed
    98. Kuri BA, Khan SA, Chan SA, Prabhakar NR, Smith CB. Increased secretory capacity of mouse adrenal chromaffin cells by chronic intermittent hypoxia: involvement of protein kinase C. J Physiol. 2007 Oct 01; 584(Pt 1):313-9. PMID: 17702812.
      View in: PubMed
    99. Kumar P, Prabhakar N. Sensing hypoxia: carotid body mechanisms and reflexes in health and disease. Respir Physiol Neurobiol. 2007 Jul 01; 157(1):1-3. PMID: 17368118.
      View in: PubMed
    100. Prabhakar NR, Peng YJ, Kumar GK, Pawar A. Altered carotid body function by intermittent hypoxia in neonates and adults: relevance to recurrent apneas. Respir Physiol Neurobiol. 2007 Jul 01; 157(1):148-53. PMID: 17317339.
      View in: PubMed
    101. Prabhakar NR. Novel role for reactive oxygen species as amplifiers of intermittent hypoxia. Focus on "Reactive oxygen species mediate central cardiorespiratory network responses to acute intermittent hypoxia". J Neurophysiol. 2007 Mar; 97(3):1877. PMID: 17215495.
      View in: PubMed
    102. Dick TE, Hsieh YH, Wang N, Prabhakar N. Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat. Exp Physiol. 2007 Jan; 92(1):87-97. PMID: 17138622.
      View in: PubMed
    103. Prabhakar NR, Dick TE, Nanduri J, Kumar GK. Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia. Exp Physiol. 2007 Jan; 92(1):39-44. PMID: 17124274.
      View in: PubMed
    104. Peng YJ, Yuan G, Ramakrishnan D, Sharma SD, Bosch-Marce M, Kumar GK, Semenza GL, Prabhakar NR. Heterozygous HIF-1alpha deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia. J Physiol. 2006 Dec 01; 577(Pt 2):705-16. PMID: 16973705.
      View in: PubMed
    105. Peng YJ, Yuan G, Jacono FJ, Kumar GK, Prabhakar NR. 5-HT evokes sensory long-term facilitation of rodent carotid body via activation of NADPH oxidase. J Physiol. 2006 Oct 01; 576(Pt 1):289-95. PMID: 16887872.
      View in: PubMed
    106. Jacono FJ, Peng YJ, Nethery D, Faress JA, Lee Z, Kern JA, Prabhakar NR. Acute lung injury augments hypoxic ventilatory response in the absence of systemic hypoxemia. J Appl Physiol (1985). 2006 Dec; 101(6):1795-802. PMID: 16888052.
      View in: PubMed
    107. Kumar GK, Rai V, Sharma SD, Ramakrishnan DP, Peng YJ, Souvannakitti D, Prabhakar NR. Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress. J Physiol. 2006 Aug 15; 575(Pt 1):229-39. PMID: 16777938.
      View in: PubMed
    108. Semenza GL, Shimoda LA, Prabhakar NR. Regulation of gene expression by HIF-1. Novartis Found Symp. 2006; 272:2-8; discussion 8-14, 33-6. PMID: 16686426.
      View in: PubMed
    109. Prabhakar NR, Peng YJ, Yuan G, Kumar GK. Reactive oxygen species facilitate oxygen sensing. Novartis Found Symp. 2006; 272:95-9; discussion 100-5, 131-40. PMID: 16686431.
      View in: PubMed
    110. Wang H, Yuan G, Prabhakar NR, Boswell M, Katz DM. Secretion of brain-derived neurotrophic factor from PC12 cells in response to oxidative stress requires autocrine dopamine signaling. J Neurochem. 2006 Feb; 96(3):694-705. PMID: 16390493.
      View in: PubMed
    111. Prabhakar NR. O2 sensing at the mammalian carotid body: why multiple O2 sensors and multiple transmitters? Exp Physiol. 2006 Jan; 91(1):17-23. PMID: 16239252.
      View in: PubMed
    112. Lahiri S, Roy A, Baby SM, Hoshi T, Semenza GL, Prabhakar NR. Oxygen sensing in the body. Prog Biophys Mol Biol. 2006 Jul; 91(3):249-86. PMID: 16137743.
      View in: PubMed
    113. Prabhakar NR, Peng YJ, Jacono FJ, Kumar GK, Dick TE. Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes. Clin Exp Pharmacol Physiol. 2005 May-Jun; 32(5-6):447-9. PMID: 15854156.
      View in: PubMed
    114. Kline DD, Buniel MC, Glazebrook P, Peng YJ, Ramirez-Navarro A, Prabhakar NR, Kunze DL. Kv1.1 deletion augments the afferent hypoxic chemosensory pathway and respiration. J Neurosci. 2005 Mar 30; 25(13):3389-99. PMID: 15800194.
      View in: PubMed
    115. Jacono FJ, Peng YJ, Kumar GK, Prabhakar NR. Modulation of the hypoxic sensory response of the carotid body by 5-hydroxytryptamine: role of the 5-HT2 receptor. Respir Physiol Neurobiol. 2005 Feb 15; 145(2-3):135-42. PMID: 15705529.
      View in: PubMed
    116. Malik MT, Peng YJ, Kline DD, Adhikary G, Prabhakar NR. Impaired ventilatory acclimatization to hypoxia in mice lacking the immediate early gene fos B. Respir Physiol Neurobiol. 2005 Jan 15; 145(1):23-31. PMID: 15652785.
      View in: PubMed
    117. Prabhakar NR, Jacono FJ. Cellular and molecular mechanisms associated with carotid body adaptations to chronic hypoxia. High Alt Med Biol. 2005; 6(2):112-20. PMID: 16060846.
      View in: PubMed
    118. Yuan G, Nanduri J, Bhasker CR, Semenza GL, Prabhakar NR. Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J Biol Chem. 2005 Feb 11; 280(6):4321-8. PMID: 15569687.
      View in: PubMed
    119. Peng YJ, Rennison J, Prabhakar NR. Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups. J Appl Physiol (1985). 2004 Nov; 97(5):2020-5. PMID: 15258129.
      View in: PubMed
    120. Yuan G, Adhikary G, McCormick AA, Holcroft JJ, Kumar GK, Prabhakar NR. Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells. J Physiol. 2004 Jun 15; 557(Pt 3):773-83. PMID: 15107478.
      View in: PubMed
    121. Dick TE, Hsieh YH, Morrison S, Coles SK, Prabhakar N. Entrainment pattern between sympathetic and phrenic nerve activities in the Sprague-Dawley rat: hypoxia-evoked sympathetic activity during expiration. Am J Physiol Regul Integr Comp Physiol. 2004 Jun; 286(6):R1121-8. PMID: 15001434.
      View in: PubMed
    122. Prabhakar NR, Kumar GK. Oxidative stress in the systemic and cellular responses to intermittent hypoxia. Biol Chem. 2004 Mar-Apr; 385(3-4):217-21. PMID: 15134334.
      View in: PubMed
    123. Prabhakar NR, Peng YJ, Overholt JL, Kumar GK. Detection of oxygen sensing during intermittent hypoxia. Methods Enzymol. 2004; 381:107-20. PMID: 15063668.
      View in: PubMed
    124. Prabhakar NR, Peng YJ. Peripheral chemoreceptors in health and disease. J Appl Physiol (1985). 2004 Jan; 96(1):359-66. PMID: 14660497.
      View in: PubMed
    125. Li YL, Sun SY, Overholt JL, Prabhakar NR, Rozanski GJ, Zucker IH, Schultz HD. Attenuated outward potassium currents in carotid body glomus cells of heart failure rabbit: involvement of nitric oxide. J Physiol. 2004 Feb 15; 555(Pt 1):219-29. PMID: 14673183.
      View in: PubMed
    126. Peng YJ, Prabhakar NR. Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity. J Appl Physiol (1985). 2004 Mar; 96(3):1236-42; discussion 1196. PMID: 14660510.
      View in: PubMed
    127. Kim DK, Natarajan N, Prabhakar NR, Kumar GK. Facilitation of dopamine and acetylcholine release by intermittent hypoxia in PC12 cells: involvement of calcium and reactive oxygen species. J Appl Physiol (1985). 2004 Mar; 96(3):1206-15; discussion 1196. PMID: 14657041.
      View in: PubMed
    128. Prabhakar NR. Regulation of breathing by tissue oxygen: evidence from mutant mice with Presbyterian hemoglobinopathy. Am J Physiol Regul Integr Comp Physiol. 2003 Oct; 285(4):R724. PMID: 12959918.
      View in: PubMed
    129. Kim DK, Prabhakar NR, Kumar GK. Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptors. J Appl Physiol (1985). 2004 Jan; 96(1):376-83. PMID: 12923121.
      View in: PubMed
    130. Peng YJ, Overholt JL, Kline D, Kumar GK, Prabhakar NR. Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):10073-8. PMID: 12907705.
      View in: PubMed
    131. Kumar GK, Prabhakar NR. Tachykinins in the control of breathing by hypoxia: pre- and post-genomic era. Respir Physiol Neurobiol. 2003 May 30; 135(2-3):145-54. PMID: 12809615.
      View in: PubMed
    132. Kumar GK, Kim DK, Lee MS, Ramachandran R, Prabhakar NR. Activation of tyrosine hydroxylase by intermittent hypoxia: involvement of serine phosphorylation. J Appl Physiol (1985). 2003 Aug; 95(2):536-44. PMID: 12692140.
      View in: PubMed
    133. Peng YJ, Prabhakar NR. Reactive oxygen species in the plasticity of respiratory behavior elicited by chronic intermittent hypoxia. J Appl Physiol (1985). 2003 Jun; 94(6):2342-9. PMID: 12533494.
      View in: PubMed
    134. Kim DK, Summers BA, Prabhakar NR, Kumar GK. Hypoxia does not uniformly facilitate the release of multiple transmitters from the carotid body. Adv Exp Med Biol. 2003; 536:291-6. PMID: 14635680.
      View in: PubMed
    135. Peng Y, Yuan G, Overholt JL, Kumar GK, Prabhakar NR. Systemic and cellular responses to intermittent hypoxia: evidence for oxidative stress and mitochondrial dysfunction. Adv Exp Med Biol. 2003; 536:559-64. PMID: 14635713.
      View in: PubMed
    136. Summers BA, Overholt JL, Prabhakar NR. CO(2) and pH independently modulate L-type Ca(2+) current in rabbit carotid body glomus cells. J Neurophysiol. 2002 Aug; 88(2):604-12. PMID: 12163513.
      View in: PubMed
    137. Yin Z, Haynie J, Yang X, Han B, Kiatchoosakun S, Restivo J, Yuan S, Prabhakar NR, Herrup K, Conlon RA, Hoit BD, Watanabe M, Yang YC. The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10488-93. PMID: 12149478.
      View in: PubMed
    138. Prabhakar NR. Sleep apneas: an oxidative stress? Am J Respir Crit Care Med. 2002 Apr 01; 165(7):859-60. PMID: 11934709.
      View in: PubMed
    139. Kline DD, Overholt JL, Prabhakar NR. Mutant mice deficient in NOS-1 exhibit attenuated long-term facilitation and short-term potentiation in breathing. J Physiol. 2002 Feb 15; 539(Pt 1):309-15. PMID: 11850522.
      View in: PubMed
    140. Kline DD, Peng YJ, Manalo DJ, Semenza GL, Prabhakar NR. Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):821-6. PMID: 11792862.
      View in: PubMed
    141. Prabhakar NR, Kline DD. Ventilatory changes during intermittent hypoxia: importance of pattern and duration. High Alt Med Biol. 2002; 3(2):195-204. PMID: 12162863.
      View in: PubMed
    142. Prabhakar NR, Fields RD, Baker T, Fletcher EC. Intermittent hypoxia: cell to system. Am J Physiol Lung Cell Mol Physiol. 2001 Sep; 281(3):L524-8. PMID: 11504675.
      View in: PubMed
    143. Clanton TL, Wright VP, Reiser PJ, Klawitter PF, Prabhakar NR. Selected Contribution: Improved anoxic tolerance in rat diaphragm following intermittent hypoxia. J Appl Physiol (1985). 2001 Jun; 90(6):2508-13. PMID: 11356820.
      View in: PubMed
    144. Prabhakar NR. Oxygen sensing during intermittent hypoxia: cellular and molecular mechanisms. J Appl Physiol (1985). 2001 May; 90(5):1986-94. PMID: 11299293.
      View in: PubMed
    145. Kim DK, Oh EK, Summers BA, Prabhakar NR, Kumar GK. Release of substance P by low oxygen in the rabbit carotid body: evidence for the involvement of calcium channels. Brain Res. 2001 Feb 23; 892(2):359-69. PMID: 11172784.
      View in: PubMed
    146. Peng Y, Kline DD, Dick TE, Prabhakar NR. Chronic intermittent hypoxia enhances carotid body chemoreceptor response to low oxygen. Adv Exp Med Biol. 2001; 499:33-8. PMID: 11729902.
      View in: PubMed
    147. Nattie EE, Prabhakar NR. Peripheral and central chemosensitivity: multiple mechanisms, multiple sites? A workshop summary. Adv Exp Med Biol. 2001; 499:73-80. PMID: 11729937.
      View in: PubMed
    148. Kline DD, Prabhakar NR. Role of nitric oxide in short-term potentiation and long-term facilitation: involvement of NO in breathing stability. Adv Exp Med Biol. 2001; 499:215-9. PMID: 11729880.
      View in: PubMed
    149. Kim DK, Summers BA, Prabhakar NR, Kumar GK. Neurotransmitter release from the rabbit carotid body: differential effects of hypoxia on substance P and acetylcholine release. Adv Exp Med Biol. 2001; 499:39-43. PMID: 11729913.
      View in: PubMed
    150. Longobardo G, Evangelisti C, Prabhakar N, Cherniack NS. Neural drives and breathing stability. Adv Exp Med Biol. 2001; 499:453-8. PMID: 11729925.
      View in: PubMed
    151. Overholt JL, Summers BA, Ficker E, Prabhakar NR. CO2/HCO3- modulates K+ and Ca2+ currents in glomus cells of the carotid body. Adv Exp Med Biol. 2001; 499:61-6. PMID: 11729935.
      View in: PubMed
    152. Adhikary G, Kline D, Yuan G, Kumar GK, Simonson MS, Cherniack NS, Prabhakar NR. Gene regulation during intermittent hypoxia: evidence for the involvement of reactive oxygen species. Adv Exp Med Biol. 2001; 499:297-302. PMID: 11729895.
      View in: PubMed
    153. Summers BA, Overholt JL, Prabhakar NR. Augmentation of L-type calcium current by hypoxia in rabbit carotid body glomus cells: evidence for a PKC-sensitive pathway. J Neurophysiol. 2000 Sep; 84(3):1636-44. PMID: 10980033.
      View in: PubMed
    154. Prabhakar NR, Overholt JL. Cellular mechanisms of oxygen sensing at the carotid body: heme proteins and ion channels. Respir Physiol. 2000 Sep; 122(2-3):209-21. PMID: 10967345.
      View in: PubMed
    155. Prabhakar NR. Oxygen sensing by the carotid body chemoreceptors. J Appl Physiol (1985). 2000 Jun; 88(6):2287-95. PMID: 10846047.
      View in: PubMed
    156. Premkumar DR, Mishra RR, Overholt JL, Simonson MS, Cherniack NS, Prabhakar NR. L-type Ca(2+) channel activation regulates induction of c-fos transcription by hypoxia. J Appl Physiol (1985). 2000 May; 88(5):1898-906. PMID: 10797155.
      View in: PubMed
    157. Kline DD, Yang T, Premkumar DR, Thomas AJ, Prabhakar NR. Blunted respiratory responses to hypoxia in mutant mice deficient in nitric oxide synthase-3. J Appl Physiol (1985). 2000 Apr; 88(4):1496-508. PMID: 10749847.
      View in: PubMed
    158. Overholt JL, Ficker E, Yang T, Shams H, Bright GR, Prabhakar NR. HERG-Like potassium current regulates the resting membrane potential in glomus cells of the rabbit carotid body. J Neurophysiol. 2000 Mar; 83(3):1150-7. PMID: 10712445.
      View in: PubMed
    159. Overholt JL, Ficker E, Yang T, Shams H, Bright GR, Prabhakar NR. Chemosensing at the carotid body. Involvement of a HERG-like potassium current in glomus cells. Adv Exp Med Biol. 2000; 475:241-8. PMID: 10849664.
      View in: PubMed
    160. Adhikary G, Premkumar DR, Prabhakar NR. Dual influence of nitric oxide on gene regulation during hypoxia. Adv Exp Med Biol. 2000; 475:285-92. PMID: 10849669.
      View in: PubMed
    161. Kline DD, Prabhakar NR. Peripheral chemosensitivity in mutant mice deficient in nitric oxide synthase. Adv Exp Med Biol. 2000; 475:571-9. PMID: 10849697.
      View in: PubMed
    162. Summers BA, Overholt JL, Prabhakar NR. Augmentation of calcium current by hypoxia in carotid body glomus cells. Adv Exp Med Biol. 2000; 475:589-99. PMID: 10849699.
      View in: PubMed
    163. Premkumar DR, Adhikary G, Overholt JL, Simonson MS, Cherniack NS, Prabhakar NR. Intracellular pathways linking hypoxia to activation of c-fos and AP-1. Adv Exp Med Biol. 2000; 475:101-9. PMID: 10849652.
      View in: PubMed
    164. Kumar GK, Kou YR, Overholt JL, Prabhakar NR. Involvement of substance P in neutral endopeptidase modulation of carotid body sensory responses to hypoxia. J Appl Physiol (1985). 2000 Jan; 88(1):195-202. PMID: 10642381.
      View in: PubMed
    165. Kumar GK, Yu RK, Overholt JL, Prabhakar NR. Role of substance P in neutral endopeptidase modulation of hypoxic response of the carotid body. Adv Exp Med Biol. 2000; 475:705-13. PMID: 10849712.
      View in: PubMed
    166. Summers BA, Overholt JL, Prabhakar NR. Nitric oxide inhibits L-type Ca2+ current in glomus cells of the rabbit carotid body via a cGMP-independent mechanism. J Neurophysiol. 1999 Apr; 81(4):1449-57. PMID: 10200181.
      View in: PubMed
    167. Prabhakar NR. NO and CO as second messengers in oxygen sensing in the carotid body. Respir Physiol. 1999 Apr 01; 115(2):161-8. PMID: 10385030.
      View in: PubMed
    168. Overholt JL, Prabhakar NR. Norepinephrine inhibits a toxin resistant Ca2+ current in carotid body glomus cells: evidence for a direct G protein mechanism. J Neurophysiol. 1999 Jan; 81(1):225-33. PMID: 9914283.
      View in: PubMed
    169. Prabhakar NR. Endogenous carbon monoxide in control of respiration. Respir Physiol. 1998 Oct; 114(1):57-64. PMID: 9858051.
      View in: PubMed
    170. Kline DD, Yang T, Huang PL, Prabhakar NR. Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase. J Physiol. 1998 Aug 15; 511 ( Pt 1):273-87. PMID: 9679181.
      View in: PubMed
    171. Mishra RR, Adhikary G, Simonson MS, Cherniack NS, Prabhakar NR. Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression. Brain Res Mol Brain Res. 1998 Aug 15; 59(1):74-83. PMID: 9729288.
      View in: PubMed
    172. Kumar GK, Overholt JL, Bright GR, Hui KY, Lu H, Gratzl M, Prabhakar NR. Release of dopamine and norepinephrine by hypoxia from PC-12 cells. Am J Physiol. 1998 Jun; 274(6 Pt 1):C1592-600. PMID: 9611124.
      View in: PubMed
    173. Ernsberger P, Kou YR, Prabhakar NR. Carotid body I1-imidazoline receptors: binding, visualization and modulatory function. Respir Physiol. 1998 Jun; 112(3):239-51. PMID: 9749948.
      View in: PubMed
    174. Overholt JL, Prabhakar NR. Ca2+ current in rabbit carotid body glomus cells is conducted by multiple types of high-voltage-activated Ca2+ channels. J Neurophysiol. 1997 Nov; 78(5):2467-74. PMID: 9356397.
      View in: PubMed
    175. Prabhakar NR, Pieramici SF, Premkumar DR, Kumar GK, Kalaria RN. Activation of nitric oxide synthase gene expression by hypoxia in central and peripheral neurons. Brain Res Mol Brain Res. 1996 Dec 31; 43(1-2):341-6. PMID: 9037552.
      View in: PubMed
    176. Zakharov SI, Pieramici S, Kumar GK, Prabhakar NR, Harvey RD. Nitric oxide synthase activity in guinea pig ventricular myocytes is not involved in muscarinic inhibition of cAMP-regulated ion channels. Circ Res. 1996 May; 78(5):925-35. PMID: 8620613.
      View in: PubMed
    177. Bright GR, Agani FH, Haque U, Overholt JL, Prabhakar NR. Heterogeneity in cytosolic calcium responses to hypoxia in carotid body cells. Brain Res. 1996 Jan 15; 706(2):297-302. PMID: 8822371.
      View in: PubMed
    178. Overholt JL, Bright GR, Prabhakar NR. Carbon monoxide and carotid body chemoreception. Adv Exp Med Biol. 1996; 410:341-4. PMID: 9030322.
      View in: PubMed
    179. Cherniack NS, Shenoy PC, Mishra R, Simonson M, Prabhakar NR. Induction of immediate early response genes by hypoxia. Possible molecular bases for systems adaptation to low pO2. Adv Exp Med Biol. 1996; 410:127-34. PMID: 9030289.
      View in: PubMed
    180. Prabhakar NR, Rao S, Premkumar D, Pieramici SF, Kumar GK, Kalaria RK. Regulation of neuronal nitric oxide synthase gene expression by hypoxia. Role of nitric oxide in respiratory adaptation to low pO2. Adv Exp Med Biol. 1996; 410:345-8. PMID: 9030323.
      View in: PubMed
    181. Prabhakar NR, Shenoy BC, Simonson MS, Cherniack NS. Cell selective induction and transcriptional activation of immediate early genes by hypoxia. Brain Res. 1995 Oct 30; 697(1-2):266-70. PMID: 8593588.
      View in: PubMed
    182. Haxhiu MA, Chang CH, Dreshaj IA, Erokwu B, Prabhakar NR, Cherniack NS. Nitric oxide and ventilatory response to hypoxia. Respir Physiol. 1995 Sep; 101(3):257-66. PMID: 8606998.
      View in: PubMed
    183. Prabhakar NR, Kou YR, Kumar GK. G proteins in carotid body chemoreception. Biol Signals. 1995 Sep-Oct; 4(5):271-6. PMID: 8704827.
      View in: PubMed
    184. Prabhakar NR, Gouda E, Kumar GK, Kou YR. Analysis of carotid chemoreceptor responses to substance P analogue in anaesthetized cats. J Auton Nerv Syst. 1995 Mar 18; 52(1):43-50. PMID: 7540190.
      View in: PubMed
    185. Prabhakar NR, Dinerman JL, Agani FH, Snyder SH. Carbon monoxide: a role in carotid body chemoreception. Proc Natl Acad Sci U S A. 1995 Mar 14; 92(6):1994-7. PMID: 7892214.
      View in: PubMed
    186. Cherniack NS, Prabhakar N, Haxhiu M. Possible genomic mechanism involved in control systems responses to hypoxia. Adv Exp Med Biol. 1995; 393:89-94. PMID: 8629528.
      View in: PubMed
    187. Prabhakar NR. Gases as chemical messengers in the carotid body. Role of nitric oxide and carbon monoxide in chemoreception. Adv Exp Med Biol. 1995; 393:309-12. PMID: 8629504.
      View in: PubMed
    188. Cragg PA, Runold M, Kou YR, Prabhakar NR. Tachykinin antagonists in carotid body responses to hypoxia and substance P in the rat. Respir Physiol. 1994 Mar; 95(3):295-310. PMID: 7520191.
      View in: PubMed
    189. Prabhakar NR. Neurotransmitters in the carotid body. Adv Exp Med Biol. 1994; 360:57-69. PMID: 7872130.
      View in: PubMed
    190. Prabhakar NR, Kou YR. Inhibitory sympathetic action on the carotid body responses to sustained hypoxia. Respir Physiol. 1994 Jan; 95(1):67-79. PMID: 7908747.
      View in: PubMed
    191. Kumar GK, Prabhakar NR, Strohl KP, Thomas A, Cragg PA. Low PO2 dependency of neutral endopeptidase and acetylcholinesterase activities of the rat carotid body. Adv Exp Med Biol. 1994; 360:217-20. PMID: 7872091.
      View in: PubMed
    192. Prabhakar NR, Cao H, Lowe JA, Snider RM. Selective inhibition of the carotid body sensory response to hypoxia by the substance P receptor antagonist CP-96,345. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):10041-5. PMID: 8234254.
      View in: PubMed
    193. Prabhakar NR, Kumar GK, Chang CH, Agani FH, Haxhiu MA. Nitric oxide in the sensory function of the carotid body. Brain Res. 1993 Oct 15; 625(1):16-22. PMID: 7694772.
      View in: PubMed
    194. Prabhakar NR, Snider RM, Lowe JA, Cao H. Selective blockade of sensory response of the carotid body to hypoxia by NK-1 receptor antagonist CP-96,345. Regul Pept. 1993 Jul 02; 46(1-2):266-8. PMID: 7692512.
      View in: PubMed
    195. Prabhakar NR, Kou YR, Cragg PA, Cherniack NS. Effect of arterial chemoreceptor stimulation: role of norepinephrine in hypoxic chemotransmission. Adv Exp Med Biol. 1993; 337:301-6. PMID: 7906485.
      View in: PubMed
    196. Cragg PA, Kou YR, Prabhakar NR. Role of substance P in rat carotid body responses to hypoxia and capsaicin. Adv Exp Med Biol. 1993; 337:265-70. PMID: 7509112.
      View in: PubMed
    197. Mitra J, Dev NB, Romaniuk JR, Trivedi R, Prabhakar NR, Cherniack NS. Cardiorespiratory changes induced by vertebral artery injection of sodium cyanide in cats. Respir Physiol. 1992 Jan; 87(1):49-61. PMID: 1553449.
      View in: PubMed
    198. Kou YR, Ernsberger P, Cragg PA, Cherniack NS, Prabhakar NR. Role of alpha 2-adrenergic receptors in the carotid body response to isocapnic hypoxia. Respir Physiol. 1991 Mar; 83(3):353-64. PMID: 1647054.
      View in: PubMed
    199. Lagercrantz H, Srinivasan M, Yamamoto Y, Prabhakar N. Functional role of substance P for respiratory control during development. Ann N Y Acad Sci. 1991; 632:48-52. PMID: 1719909.
      View in: PubMed
    200. Prabhakar NR. Chemoreceptor responses to substance P, physalaemin and eledoisin: evidence for neurokinin-1 receptors in the cat carotid body. Neurosci Lett. 1990 Dec 11; 120(2):183-6. PMID: 1705679.
      View in: PubMed
    201. Kumar GK, Runold M, Ghai RD, Cherniack NS, Prabhakar NR. Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception. Brain Res. 1990 May 28; 517(1-2):341-3. PMID: 2376002.
      View in: PubMed
    202. Runold M, Cherniack NS, Prabhakar NR. Effect of adenosine on isolated and superfused cat carotid body activity. Neurosci Lett. 1990 May 18; 113(1):111-4. PMID: 2366949.
      View in: PubMed
    203. Runold M, Cherniack NS, Prabhakar NR. Effect of adenosine on chemosensory activity of the cat aortic body. Respir Physiol. 1990 May-Jun; 80(2-3):299-306. PMID: 2218102.
      View in: PubMed
    204. Mitra J, Prabhakar NR, Overholt JL, Cherniack NS. Respiratory effects of N-methyl-D-aspartate on the ventrolateral medullary surface. J Appl Physiol (1985). 1989 Nov; 67(5):1814-9. PMID: 2574718.
      View in: PubMed
    205. Prabhakar NR, Runold M, Kumar GK, Cherniack NS, Scarpa A. Substance P and mitochondrial oxygen consumption: evidence for a direct intracellular role for the peptide. Peptides. 1989 Sep-Oct; 10(5):1003-6. PMID: 2481845.
      View in: PubMed
    206. Runold M, Lagercrantz H, Prabhakar NR, Fredholm BB. Role of adenosine in hypoxic ventilatory depression. J Appl Physiol (1985). 1989 Aug; 67(2):541-6. PMID: 2793655.
      View in: PubMed
    207. Prabhakar NR, Landis SC, Kumar GK, Mullikin-Kilpatrick D, Cherniack NS, Leeman S. Substance P and neurokinin A in the cat carotid body: localization, exogenous effects and changes in content in response to arterial pO2. Brain Res. 1989 Mar 06; 481(2):205-14. PMID: 2470465.
      View in: PubMed
    208. Prabhakar NR, Mitra J, Adams EM, Cherniack NS. Involvement of ventral medullary surface in respiratory responses induced by 2,4-dinitrophenol. J Appl Physiol (1985). 1989 Feb; 66(2):598-605. PMID: 2708191.
      View in: PubMed
    209. Cherniack NS, Adams EM, Prabhakar NR, Haxhiu M, Mitra J. Integration of cardiorespiratory responses in the ventrolateral medulla. Prog Brain Res. 1989; 81:215-20. PMID: 2616783.
      View in: PubMed
    210. Yamamoto Y, Runold M, Prabhakar N, Pantaleo T, Lagercrantz H. Somatostatin in the control of respiration. Acta Physiol Scand. 1988 Dec; 134(4):529-33. PMID: 2907961.
      View in: PubMed
    211. Overholt JL, Mitra J, van Lunteren E, Prabhakar NR, Cherniack NS. Naloxone enhances the response to hypercapnia of spinal and cranial respiratory nerves. Respir Physiol. 1988 Dec; 74(3):299-309. PMID: 3222562.
      View in: PubMed
    212. Mitra J, Prabhakar NR, Overholt JL, Cherniack NS. Respiratory and vasomotor responses to focal cooling of the ventral medullary surface (VMS) of the rat. Respir Physiol. 1988 Oct; 74(1):35-47. PMID: 3187204.
      View in: PubMed
    213. van Lunteren E, Prabhakar NR, Cherniack NS, Haxhiu MA, Dick TE. Inhibition of expiratory muscle EMG and motor unit activity during augmented breaths in cats. Respir Physiol. 1988 Jun; 72(3):303-14. PMID: 3406552.
      View in: PubMed
    214. Cherniack NS, Mitra J, Prabhakar NR, Adams EM. Respiratory and vasomotor influences of the ventrolateral medulla. Clin Exp Hypertens A. 1988; 10 Suppl 1:1-9. PMID: 3072119.
      View in: PubMed
    215. Kieschke J, Mense S, Prabhakar NR. Influence of adrenaline and hypoxia on rat muscle receptors in vitro. Prog Brain Res. 1988; 74:91-7. PMID: 2973083.
      View in: PubMed
    216. Prabhakar NR, Mitra J, Cherniack NS. Role of substance P in hypercapnic excitation of carotid chemoreceptors. J Appl Physiol (1985). 1987 Dec; 63(6):2418-25. PMID: 2449416.
      View in: PubMed
    217. Prabhakar NR, Runold M, Yamamoto Y, Lagercrantz H, Cherniack NS, von Euler C. Role of the vagal afferents in substance P-induced respiratory responses in anaesthetized rabbits. Acta Physiol Scand. 1987 Sep; 131(1):63-71. PMID: 2445172.
      View in: PubMed
    218. Van Lunteren E, Mitra J, Prabhakar NR, Haxhiu MA, Cherniack NS. Ventral medullary surface inputs to cervical sympathetic respiratory oscillations. Am J Physiol. 1987 Jun; 252(6 Pt 2):R1032-8. PMID: 3109263.
      View in: PubMed
    219. Mitra J, Prabhakar NR, Overholt JL, Cherniack NS. Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface. Brain Res Bull. 1987 May; 18(5):681-4. PMID: 2886198.
      View in: PubMed
    220. Prabhakar NR, Mitra J, Overholt JL, Cherniack NS. Analysis of postinspiratory activity of phrenic motoneurons with chemical and vagal reflexes. J Appl Physiol (1985). 1986 Oct; 61(4):1499-509. PMID: 3096939.
      View in: PubMed
    221. Prabhakar NR, Mitra J, Van de Graaff W, Haxhiu MA, Cherniack NS. Effect of focal cooling of central chemosensitive areas on cerebral ischemic response. Am J Physiol. 1986 Aug; 251(2 Pt 2):R295-302. PMID: 2874745.
      View in: PubMed
    222. Mitra J, Prabhakar NR, Haxhiu M, Cherniack NS. Comparison of the effects of hypercapnia on phrenic and hypoglossal activity in anesthetized decerebrate and decorticate animals. Brain Res Bull. 1986 Aug; 17(2):181-7. PMID: 3768733.
      View in: PubMed
    223. Mense S, Prabhakar NR. Spinal termination of nociceptive afferent fibres from deep tissues in the cat. Neurosci Lett. 1986 May 15; 66(2):169-74. PMID: 3725183.
      View in: PubMed
    224. Haxhiu MA, Mitra J, van Lunteren E, Prabhakar N, Bruce EN, Cherniack NS. Responses of hypoglossal and phrenic nerves to decreased respiratory drive in cats. Respiration. 1986; 50(2):130-8. PMID: 3749614.
      View in: PubMed
    225. Haxhiu MA, Mitra J, van Lunteren E, Prabhakar NR, Cherniack NS. Influence of central chemoreceptor afferent inputs on respiratory muscle activity. Am J Physiol. 1985 Aug; 249(2 Pt 2):R266-73. PMID: 4025583.
      View in: PubMed
    226. Mitra J, Prabhakar NR, Haxhiu MA, Cherniack NS. The effects of hypercapnia and cooling the ventral medullary surface on capsaicin induced respiratory reflexes. Respir Physiol. 1985 Jun; 60(3):377-85. PMID: 3929349.
      View in: PubMed
    227. Prabhakar NR, Marek W, Loeschcke HH. Altered breathing pattern elicited by stimulation of abdominal visceral afferents. J Appl Physiol (1985). 1985 Jun; 58(6):1755-60. PMID: 4008397.
      View in: PubMed
    228. Marek W, Prabhakar NR. Electrical stimulation of arterial and central chemosensory afferents at different times in the respiratory cycle of the cat: II. Responses of respiratory muscles and their motor nerves. Pflugers Arch. 1985 Apr; 403(4):422-8. PMID: 3160005.
      View in: PubMed
    229. Marek W, Prabhakar NR, Loeschcke HH. Electrical stimulation of arterial and central chemosensory afferents at different times in the respiratory cycle of the cat: I. Ventilatory responses. Pflugers Arch. 1985 Apr; 403(4):415-21. PMID: 4011393.
      View in: PubMed
    230. Prabhakar NR, Runold M, Yamamoto Y, Lagercrantz H, von Euler C. Effect of substance P antagonist on the hypoxia-induced carotid chemoreceptor activity. Acta Physiol Scand. 1984 Jul; 121(3):301-3. PMID: 6206685.
      View in: PubMed
    231. Funke PJ, Prabhakar NR, Hertle L, Runkel N, Dahlheim H. Plasma renin activity and cardiovascular changes in patients with chronic bladder distension. Urol Int. 1982; 37(5):363-8. PMID: 6760517.
      View in: PubMed
    232. Prabhakar NR, Nishith SD, Saxena JP. Effect of distension of urinary bladder on blood pressure and respiration. Indian J Physiol Pharmacol. 1973 Oct-Dec; 17(4):370-5. PMID: 4802452.
      View in: PubMed
    PRABHAKAR's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _