AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase
"AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dioxygenase and alkylation repair homolog that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. It has a strong preference for SINGLE-STRANDED DNA and may also act on RNA.
| Descriptor ID |
D000071500
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| MeSH Number(s) |
D08.811.074.062.875 D08.811.682.690.416.139.875
|
| Concept/Terms |
AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase- AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase
- AlkB Homolog 3, Alpha Ketoglutarate Dependent Dioxygenase
- Prostate Cancer Antigen 1
- Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3
- Alpha Ketoglutarate Dependent Dioxygenase AlkB Homolog 3
- Alkylated DNA Repair Protein AlkB Homolog 3
|
Below are MeSH descriptors whose meaning is more general than "AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase".
Below are MeSH descriptors whose meaning is more specific than "AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase".
This graph shows the total number of publications written about "AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase" by people in this website by year, and whether "AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase" by people in Profiles.
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The Molecular Basis of Human ALKBH3 Mediated RNA N1 -methyladenosine (m1 A) Demethylation. Angew Chem Int Ed Engl. 2024 Feb 12; 63(7):e202313900.
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Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature. 2010 Nov 11; 468(7321):330-3.
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A non-heme iron-mediated chemical demethylation in DNA and RNA. Acc Chem Res. 2009 Apr 21; 42(4):519-29.
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Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins. J Am Chem Soc. 2005 Oct 26; 127(42):14594-5.
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Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies. Nucleic Acids Res. 2004; 32(4):1548-54.