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Sosnick, Tobin R.
One or more keywords matched the following items that are connected to Sosnick, Tobin R.
Item TypeName
Concept Avidin
Concept Bacillus
Concept Cyclic AMP
Concept Algorithms
Concept Bordetella pertussis
Concept Calmodulin
Concept Analysis of Variance
Concept Antibodies, Monoclonal
Concept Geobacillus stearothermophilus
Concept Base Sequence
Concept Cations, Divalent
Concept Deuterium
Concept Bayes Theorem
Concept Biotin
Concept Bacillus subtilis
Concept Endoribonucleases
Concept Cattle
Concept Genetic Vectors
Concept Cobamides
Concept Cysteine
Concept Hydrogen
Concept Imidazoles
Concept Dinitrocresols
Concept Insulysin
Concept Disulfides
Concept Dithiothreitol
Concept Cations, Monovalent
Concept DNA Mutational Analysis
Concept Fluoresceins
Concept Chromatography, High Pressure Liquid
Concept Ethylenediamines
Concept Enzyme Activation
Concept Fluorescence
Concept Nucleic Acid Hybridization
Concept Ribonuclease T1
Concept Health Planning Guidelines
Concept DNA, Viral
Concept Hydrogen-Ion Concentration
Concept Escherichia coli
Concept Fourier Analysis
Concept Gait
Concept Light
Concept Models, Genetic
Concept Markov Chains
Concept Monte Carlo Method
Concept Micrococcal Nuclease
Concept Mutation
Concept Hot Temperature
Concept Nucleic Acid Conformation
Concept Endopeptidases
Concept Microscopy, Electron
Concept Flavin Mononucleotide
Concept Probability
Concept Plasmids
Concept Protein Processing, Post-Translational
Concept Forecasting
Concept Immunoglobulin G
Concept Rabbits
Concept Vitamin B 12
Concept X-Ray Diffraction
Concept Regulatory Sequences, Nucleic Acid
Concept Ribonuclease, Pancreatic
Concept RNA Processing, Post-Transcriptional
Concept Humans
Concept Cluster Analysis
Concept Stress, Mechanical
Concept Protein Engineering
Concept Hair Cells, Auditory, Outer
Concept X-Rays
Concept Cryoelectron Microscopy
Concept Mitogen-Activated Protein Kinases
Concept Range of Motion, Articular
Concept Zebrafish Proteins
Concept Observer Variation
Concept Mutagenesis, Site-Directed
Concept Sequence Alignment
Concept Walking
Concept Alternative Splicing
Concept Treatment Outcome
Concept Point Mutation
Concept Crystallography, X-Ray
Concept Gene Expression Regulation, Developmental
Concept Phosphatidylethanolamine Binding Protein
Concept Pliability
Concept Halogenation
Concept Nucleic Acid Denaturation
Concept Riboswitch
Concept bcl-2-Associated X Protein
Concept Guanidine
Concept Amino Acid Substitution
Concept 5' Untranslated Regions
Concept Base Pairing
Concept Polyethylene Glycols
Concept Saccharomyces cerevisiae Proteins
Concept Databases, Protein
Concept Mice
Concept Ribonucleases
Concept Saccharomyces cerevisiae
Concept Inverted Repeat Sequences
Concept Static Electricity
Concept Torsion, Mechanical
Concept Temperature
Concept Models, Statistical
Concept Tetrahymena
Concept Trifluoroethanol
Concept Reproducibility of Results
Concept Inovirus
Concept Amyloid beta-Peptides
Concept GTP-Binding Proteins
Concept Sequence Analysis, Protein
Concept Microscopy, Atomic Force
Concept Peptide Library
Concept Kv1.2 Potassium Channel
Concept RNA Folding
Concept Cryptochromes
Concept Alzheimer Disease
Concept Artificial Intelligence
Concept Cloning, Molecular
Concept Data Interpretation, Statistical
Concept DNA, Single-Stranded
Concept Fluorescent Dyes
Concept Histidine
Concept Horses
Concept Kinetics
Concept Lactoglobulins
Concept Pain Measurement
Concept Protons
Concept Restriction Mapping
Concept Transcriptional Activation
Concept Gene Expression Regulation, Bacterial
Concept Hydroxyl Radical
Concept Computational Biology
Concept Ribonuclease P
Concept Protein Kinase Inhibitors
Concept Nucleotide Motifs
Academic Article Biogenesis of pyrroloquinoline quinone from 3C-labeled tyrosine.
Academic Article Solution structure of the cAMP-dependent protein kinase catalytic subunit and its contraction upon binding the protein kinase inhibitor peptide.
Academic Article The role of helix formation in the folding of a fully alpha-helical coiled coil.
Academic Article Applicability of urea in the thermodynamic analysis of secondary and tertiary RNA folding.
Academic Article Thymosin beta 4 binds actin in an extended conformation and contacts both the barbed and pointed ends.
Academic Article Distinguishing between two-state and three-state models for ubiquitin folding.
Academic Article Denatured states of ribonuclease A have compact dimensions and residual secondary structure.
Academic Article Altering the intermediate in the equilibrium folding of unmodified yeast tRNAPhe with monovalent and divalent cations.
Academic Article Viscosity dependence of the folding kinetics of a dimeric and monomeric coiled coil.
Academic Article Mg2+-dependent compaction and folding of yeast tRNAPhe and the catalytic domain of the B. subtilis RNase P RNA determined by small-angle X-ray scattering.
Academic Article Pathway modulation, circular permutation and rapid RNA folding under kinetic control.
Academic Article Trifluoroethanol promotes helix formation by destabilizing backbone exposure: desolvation rather than native hydrogen bonding defines the kinetic pathway of dimeric coiled coil folding.
Academic Article Dynamics of hydrogen bond desolvation in protein folding.
Academic Article A thermodynamic framework and cooperativity in the tertiary folding of a Mg2+-dependent ribozyme.
Academic Article Entropic benefit of a cross-link in protein association.
Academic Article Application of circular dichroism to study RNA folding transitions.
Academic Article Modular construction of a tertiary RNA structure: the specificity domain of the Bacillus subtilis RNase P RNA.
Academic Article Distances between the antigen-binding sites of three murine antibody subclasses measured using neutron and X-ray scattering.
Academic Article Investigations into sequence and conformational dependence of backbone entropy, inter-basin dynamics and the Flory isolated-pair hypothesis for peptides.
Academic Article Discerning the structure and energy of multiple transition states in protein folding using psi-analysis.
Academic Article Fast and slow intermediate accumulation and the initial barrier mechanism in protein folding.
Academic Article Fast folding of a helical protein initiated by the collision of unstructured chains.
Academic Article Comment on "Force-clamp spectroscopy monitors the folding trajectory of a single protein".
Academic Article RNA folding: models and perspectives.
Academic Article Characterizing protein folding transition States using Psi-analysis.
Academic Article PII structure in the model peptides for unfolded proteins: studies on ubiquitin fragments and several alanine-rich peptides containing QQQ, SSS, FFF, and VVV.
Academic Article RNA folding during transcription.
Academic Article A large collapsed-state RNA can exhibit simple exponential single-molecule dynamics.
Academic Article Random-coil behavior and the dimensions of chemically unfolded proteins.
Academic Article Quantifying the structural requirements of the folding transition state of protein A and other systems.
Academic Article Light-activated DNA binding in a designed allosteric protein.
Academic Article Reduced contact order and RNA folding rates.
Academic Article Psi-constrained simulations of protein folding transition states: implications for calculating.
Academic Article Small proteins fold through transition states with native-like topologies.
Academic Article Extended structures in RNA folding intermediates are due to nonnative interactions rather than electrostatic repulsion.
Academic Article Protein vivisection reveals elusive intermediates in folding.
Academic Article Reduced C(beta) statistical potentials can outperform all-atom potentials in decoy identification.
Academic Article Small-angle X-ray scattering and single-molecule FRET spectroscopy produce highly divergent views of the low-denaturant unfolded state.
Academic Article Transcriptional pausing coordinates folding of the aptamer domain and the expression platform of a riboswitch.
Academic Article TULIPs: tunable, light-controlled interacting protein tags for cell biology.
Academic Article Biochemistry. How proteins fold.
Academic Article Probing the folding transition state of ubiquitin mutants by temperature-jump-induced downhill unfolding.
Academic Article Structure of a folding intermediate reveals the interplay between core and peripheral elements in RNA folding.
Academic Article Protein structure prediction enhanced with evolutionary diversity: SPEED.
Academic Article The folding transition state of protein L is extensive with nonnative interactions (and not small and polarized).
Academic Article Fully reduced ribonuclease A does not expand at high denaturant concentration or temperature.
Academic Article Stepwise conversion of a mesophilic to a thermophilic ribozyme.
Academic Article Early collapse is not an obligate step in protein folding.
Academic Article Statistical coil model of the unfolded state: resolving the reconciliation problem.
Academic Article Minimalist representations and the importance of nearest neighbor effects in protein folding simulations.
Academic Article Mimicking the folding pathway to improve homology-free protein structure prediction.
Academic Article Context and force field dependence of the loss of protein backbone entropy upon folding using realistic denatured and native state ensembles.
Academic Article Discovering RNA-protein interactome by using chemical context profiling of the RNA-protein interface.
Academic Article Investigating models of protein function and allostery with a widespread mutational analysis of a light-activated protein.
Academic Article Introduction of a polar core into the de novo designed protein Top7.
Academic Article Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water.
Academic Article A Membrane Burial Potential with H-Bonds and Applications to Curved Membranes and Fast Simulations.
Academic Article Response to Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water".
Academic Article Trajectory-based training enables protein simulations with accurate folding and Boltzmann ensembles in cpu-hours.
Academic Article Accurate calculation of side chain packing and free energy with applications to protein molecular dynamics.
Academic Article Commonly used FRET fluorophores promote collapse of an otherwise disordered protein.
Academic Article Helical Contributions Mediate Light-Activated Conformational Change in the LOV2 Domain of Avena sativa Phototropin 1.
Academic Article On the Interpretation of Force-Induced Unfolding Studies of Membrane Proteins Using Fast Simulations.
Academic Article Structural basis for adhesion G protein-coupled receptor Gpr126 function.
Academic Article Water as a Good Solvent for Unfolded Proteins: Folding and Collapse are Fundamentally Different.
Academic Article Properties of protein unfolded states suggest broad selection for expanded conformational ensembles.
Academic Article Molecular dynamics study of water channels in natural and synthetic amyloid-ß fibrils.
Academic Article Folding and misfolding of potassium channel monomers during assembly and tetramerization.
Academic Article Engineered Metal-Binding Sites to Probe Protein Folding Transition States: Psi Analysis.
Academic Article Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence.
Academic Article Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein.
Academic Article Challenges and Advantages of Accounting for Backbone Flexibility in Prediction of Protein-Protein Complexes.
Academic Article HDX-MS performed on BtuB in E. coli outer membranes delineates the luminal domain's allostery and unfolding upon B12 and TonB binding.
Academic Article Development of in vivo HDX-MS with applications to a TonB-dependent transporter and other proteins.
Academic Article LILAC: enhanced actin imaging with an optogenetic Lifeact.
Academic Article Factors That Control the Force Needed to Unfold a Membrane Protein in Silico Depend on the Mode of Denaturation.
Concept Dynamic Light Scattering
Concept Machine Learning
Concept Optogenetics
Academic Article Folding of Prestin's Anion-Binding Site and the Mechanism of Outer Hair Cell Electromotility.
Academic Article AlphaFold developers Demis Hassabis and John Jumper share the 2023 Albert Lasker Basic Medical Research Award.
Academic Article An adaptive biomolecular condensation response is conserved across environmentally divergent species.
Academic Article Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility.
Academic Article HDX-MS finds that partial unfolding with sequential domain activation controls condensation of a cellular stress marker.
Academic Article How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins.
Academic Article An adaptive biomolecular condensation response is conserved across environmentally divergent species.
Search Criteria
  • Kv1
  • 3
  • Potassium Channel