Item Type | Name |
Concept
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Fungal Proteins
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Concept
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Chromosomal Proteins, Non-Histone
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Concept
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DNA-Binding Proteins
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Concept
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Eye Proteins
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Concept
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Membrane Proteins
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Concept
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Nerve Tissue Proteins
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Concept
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Heat-Shock Proteins
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Concept
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Protein-Tyrosine Kinases
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Concept
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Protein Binding
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Concept
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Protein Conformation
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Concept
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Protein Processing, Post-Translational
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Concept
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Proto-Oncogene Proteins
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Concept
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Repressor Proteins
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Concept
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Protein Kinases
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Concept
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Insect Proteins
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Concept
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Protein Structure, Quaternary
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Concept
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Mitogen-Activated Protein Kinases
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Concept
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Protein Structure, Tertiary
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Concept
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RNA-Binding Proteins
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Concept
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HSP70 Heat-Shock Proteins
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Concept
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ras Proteins
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Concept
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Wnt1 Protein
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Concept
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Receptor Protein-Tyrosine Kinases
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Concept
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Protein Transport
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Concept
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Drosophila Proteins
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Concept
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Xenopus Proteins
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Concept
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Protein Tyrosine Phosphatases
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Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Green Fluorescent Proteins
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Concept
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Proto-Oncogene Proteins c-ets
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Concept
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Cell Cycle Proteins
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Concept
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Mitogen-Activated Protein Kinase Kinases
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Concept
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Schizosaccharomyces pombe Proteins
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Concept
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Proto-Oncogene Protein c-ets-2
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Concept
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Wnt Proteins
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Concept
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Focal Adhesion Protein-Tyrosine Kinases
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Concept
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Recombinant Proteins
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Concept
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Hedgehog Proteins
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Concept
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Protein Interaction Domains and Motifs
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Concept
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Protein Multimerization
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Concept
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Proto-Oncogene Proteins p21(ras)
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Concept
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GTP-Binding Proteins
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Concept
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Calcium-Calmodulin-Dependent Protein Kinases
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Concept
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Son of Sevenless Protein, Drosophila
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Concept
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Homeodomain Proteins
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Concept
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JNK Mitogen-Activated Protein Kinases
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Concept
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Proto-Oncogene Protein c-ets-1
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Amyloid Precursor Protein Secretases
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Concept
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Calcium-Binding Proteins
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Concept
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Carrier Proteins
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Concept
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Nuclear Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Protein Isoforms
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Concept
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p38 Mitogen-Activated Protein Kinases
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Academic Article
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An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye.
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Academic Article
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Expression of DFak56, a Drosophila homolog of vertebrate focal adhesion kinase, supports a role in cell migration in vivo.
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Academic Article
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Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor.
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Academic Article
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Signal transduction downstream from Ras in Drosophila.
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Academic Article
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split ends, a new component of the Drosophila EGF receptor pathway, regulates development of midline glial cells.
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Academic Article
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Biological functions of the ISWI chromatin remodeling complex NURF.
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Academic Article
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Eyes absent mediates cross-talk between retinal determination genes and the receptor tyrosine kinase signaling pathway.
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Academic Article
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CRM1-mediated nuclear export and regulated activity of the Receptor Tyrosine Kinase antagonist YAN require specific interactions with MAE.
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Academic Article
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Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network.
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Academic Article
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The novel plant homeodomain protein rhinoceros antagonizes Ras signaling in the Drosophila eye.
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Academic Article
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The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila.
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Academic Article
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Splits ends is a tissue/promoter specific regulator of Wingless signaling.
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Academic Article
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Keeping the receptor tyrosine kinase signaling pathway in check: lessons from Drosophila.
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Academic Article
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Derepression by depolymerization; structural insights into the regulation of Yan by Mae.
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Academic Article
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MAE, a dual regulator of the EGFR signaling pathway, is a target of the Ets transcription factors PNT and YAN.
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Academic Article
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Using Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absent.
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Academic Article
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New vision from Eyes absent: transcription factors as enzymes.
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Academic Article
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Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function.
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Academic Article
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Signaling circuitries in development: insights from the retinal determination gene network.
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Academic Article
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Intersection of signal transduction pathways and development.
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Academic Article
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The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis.
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Academic Article
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Molecular genetics of spinocerebellar ataxia type 8 (SCA8).
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Academic Article
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The transcription factor Eyes absent is a protein tyrosine phosphatase.
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Academic Article
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The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis.
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Academic Article
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Identification of transcriptional targets of the dual-function transcription factor/phosphatase eyes absent.
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Academic Article
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Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm.
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Academic Article
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Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talk.
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Academic Article
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Sterile alpha motif domain-mediated self-association plays an essential role in modulating the activity of the Drosophila ETS family transcriptional repressor Yan.
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Academic Article
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Preparation of soluble GST fusion proteins.
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Academic Article
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Preparation of insoluble GST fusion proteins.
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Academic Article
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Split ends antagonizes the Notch and potentiates the EGFR signaling pathways during Drosophila eye development.
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Academic Article
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Notch and the molecular genetics of neuroblast segregation in Drosophila.
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Academic Article
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The SAM domain of human TEL2 can abrogate transcriptional output from TEL1 (ETV-6) and ETS1/ETS2.
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Academic Article
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Nemo phosphorylates Eyes absent and enhances output from the Eya-Sine oculis transcriptional complex during Drosophila retinal determination.
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Academic Article
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Abelson tyrosine kinase is required for Drosophila photoreceptor morphogenesis and retinal epithelial patterning.
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Academic Article
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Characterization of the split ends-like gene spenito reveals functional antagonism between SPOC family members during Drosophila eye development.
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Academic Article
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Dot blot assay for determining fusion protein antiserum quality.
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Academic Article
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Determining fusion protein antiserum quality by staining of transfected Drosophila S2 cultured cells.
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Academic Article
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Ras signal transduction pathway in Drosophila eye development.
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Academic Article
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The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription.
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Academic Article
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The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway.
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Academic Article
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Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor.
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Academic Article
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Analysis of phenotypic abnormalities and cell fate changes caused by dominant activated and dominant negative forms of the Notch receptor in Drosophila development.
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Academic Article
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Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway.
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Academic Article
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A genetic screen for novel components of the Ras/Mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RNA recognition motif-containing protein.
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Academic Article
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Signal integration during development: insights from the Drosophila eye.
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Academic Article
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New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.
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Academic Article
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Post-translational modifications influence transcription factor activity: a view from the ETS superfamily.
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Academic Article
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Function of the ETS transcription factor Yan in border cell migration.
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Academic Article
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Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila.
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Academic Article
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The Abelson tyrosine kinase regulates Notch endocytosis and signaling to maintain neuronal cell fate in Drosophila photoreceptors.
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Academic Article
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Chromatin occupancy patterns of the ETS repressor Yan: a mechanism for buffering gene expression against noise?
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Academic Article
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The relationship between long-range chromatin occupancy and polymerization of the Drosophila ETS family transcriptional repressor Yan.
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Academic Article
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Onset of atonal expression in Drosophila retinal progenitors involves redundant and synergistic contributions of Ey/Pax6 and So binding sites within two distant enhancers.
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Academic Article
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3D chromatin interactions organize Yan chromatin occupancy and repression at the even-skipped locus.
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Academic Article
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A comparative study of Pointed and Yan expression reveals new complexity to the transcriptional networks downstream of receptor tyrosine kinase signaling.
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Academic Article
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Long-range integration of repressive and patterning inputs.
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Academic Article
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Dynamics and heterogeneity of a fate determinant during transition towards cell differentiation.
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Academic Article
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Multiple Functions of the Eya Phosphotyrosine Phosphatase.
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Academic Article
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Retinal Axon Guidance Requires Integration of Eya and the Jak/Stat Pathway into Phosphotyrosine-Based Signaling Circuitries in Drosophila.
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Academic Article
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DNA Occupancy of Polymerizing Transcription Factors: A Chemical Model of the ETS Family Factor Yan.
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Academic Article
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Antagonistic regulation of the second mitotic wave by Eyes absent-Sine oculis and Combgap coordinates proliferation and specification in the Drosophila retina.
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Academic Article
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Pleiotropy in Drosophila organogenesis: Mechanistic insights from Combgap and the retinal determination gene network.
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Academic Article
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Mutations that impair Eyes absent tyrosine phosphatase activity in vitro reduce robustness of retinal determination gene network output in Drosophila.
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Academic Article
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Tuned polymerization of the transcription factor Yan limits off-DNA sequestration to confer context-specific repression.
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Academic Article
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Cooperative recruitment of Yan via a high-affinity ETS supersite organizes repression to confer specificity and robustness to cardiac cell fate specification.
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Academic Article
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Collaborative repressive action of the antagonistic ETS transcription factors Pointed and Yan fine-tunes gene expression to confer robustness in Drosophila.
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Academic Article
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A context-dependent bifurcation in the Pointed transcriptional effector network contributes specificity and robustness to retinal cell fate acquisition.
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Concept
|
Serrate-Jagged Proteins
|
Concept
|
Jagged-1 Protein
|
Concept
|
Protein Aggregates
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Grant
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Specificity and dynamics of transcriptional repression in retinal development
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Academic Article
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Ratiometric sensing of Pnt and Yan transcription factor levels confers ultrasensitivity to photoreceptor fate transitions in Drosophila.
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Academic Article
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Inter-plane feedback coordinates cell morphogenesis and maintains 3D tissue organization in the Drosophila pupal retina.
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