Histocompatibility Antigens Class I
"Histocompatibility Antigens Class I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
| Descriptor ID |
D015395
|
| MeSH Number(s) |
D12.776.395.550.489 D12.776.543.550.439 D23.050.301.500.100 D23.050.705.552.100
|
| Concept/Terms |
Histocompatibility Antigens Class I- Histocompatibility Antigens Class I
- Class I Histocompatibility Antigens
- Class I Antigens
- Antigens, Class I
- I Antigens, Class
- Class I Major Histocompatibility Antigens
|
Below are MeSH descriptors whose meaning is more general than "Histocompatibility Antigens Class I".
Below are MeSH descriptors whose meaning is more specific than "Histocompatibility Antigens Class I".
This graph shows the total number of publications written about "Histocompatibility Antigens Class I" by people in this website by year, and whether "Histocompatibility Antigens Class I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 0 | 2 |
| 1994 | 2 | 2 | 4 |
| 1995 | 4 | 2 | 6 |
| 1996 | 4 | 1 | 5 |
| 1997 | 7 | 0 | 7 |
| 1998 | 3 | 3 | 6 |
| 1999 | 7 | 6 | 13 |
| 2000 | 2 | 1 | 3 |
| 2001 | 5 | 5 | 10 |
| 2002 | 6 | 2 | 8 |
| 2003 | 5 | 1 | 6 |
| 2004 | 4 | 0 | 4 |
| 2005 | 8 | 4 | 12 |
| 2006 | 3 | 0 | 3 |
| 2007 | 4 | 2 | 6 |
| 2008 | 4 | 3 | 7 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 2 | 4 |
| 2011 | 3 | 1 | 4 |
| 2012 | 4 | 3 | 7 |
| 2013 | 5 | 0 | 5 |
| 2014 | 2 | 5 | 7 |
| 2015 | 1 | 1 | 2 |
| 2016 | 5 | 0 | 5 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2019 | 0 | 2 | 2 |
| 2020 | 2 | 2 | 4 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Histocompatibility Antigens Class I" by people in Profiles.
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Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells. Sci Rep. 2022 12 29; 12(1):22539.
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De novo human leukocyte antigen allosensitization patterns in patients bridged to heart transplantation using left ventricular assist devices. Transpl Immunol. 2022 06; 72:101567.
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Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection. Nat Commun. 2021 07 16; 12(1):4372.
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Safety, Tolerability, and Activity of ALXN1830 Targeting the Neonatal Fc Receptor in Chronic Pemphigus. J Invest Dermatol. 2021 12; 141(12):2858-2865.e4.
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Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin-10 in Murine Models. Arthritis Rheumatol. 2021 05; 73(5):769-778.
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Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer. Nat Commun. 2020 11 04; 11(1):5583.
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Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy. J Hematol Oncol. 2020 06 09; 13(1):74.
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Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2. J Hum Genet. 2020 Jul; 65(7):569-575.
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Production of MR1 Tetramers Loaded with Microbial Ligands. Methods Mol Biol. 2020; 2098:191-207.
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MAIT cells are imprinted by the microbiota in early life and promote tissue repair. Science. 2019 10 25; 366(6464).