 beta Catenin
"beta Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.
| Descriptor ID |
D051176
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| MeSH Number(s) |
D12.776.091.249 D12.776.220.145.500 D12.776.930.130
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta Catenin".
Below are MeSH descriptors whose meaning is more specific than "beta Catenin".
This graph shows the total number of publications written about "beta Catenin" by people in this website by year, and whether "beta Catenin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 5 | 5 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 4 | 4 | | 2002 | 0 | 12 | 12 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 7 | 7 | | 2005 | 1 | 5 | 6 | | 2006 | 2 | 2 | 4 | | 2007 | 3 | 5 | 8 | | 2008 | 4 | 3 | 7 | | 2009 | 3 | 2 | 5 | | 2010 | 9 | 1 | 10 | | 2011 | 4 | 6 | 10 | | 2012 | 4 | 2 | 6 | | 2013 | 7 | 5 | 12 | | 2014 | 5 | 3 | 8 | | 2015 | 5 | 2 | 7 | | 2016 | 0 | 5 | 5 | | 2017 | 3 | 5 | 8 | | 2018 | 2 | 2 | 4 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta Catenin" by people in Profiles.
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Luke JJ, Bao R, Sweis RF, Spranger S, Gajewski TF. WNT/ß-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers. Clin Cancer Res. 2019 May 15; 25(10):3074-3083.
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Corean J, Furtado LV, Kadri S, Segal JP, Emerson LL. Cribriform-Morular Variant of Papillary Thyroid Carcinoma With Poorly Differentiated Features: A Case Report With Immunohistochemical and Molecular Genetic Analysis. Int J Surg Pathol. 2019 May; 27(3):294-304.
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Ishihara J, Ishihara A, Potin L, Hosseinchi P, Fukunaga K, Damo M, Gajewski TF, Swartz MA, Hubbell JA. Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity. Mol Cancer Ther. 2018 11; 17(11):2399-2411.
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Kim G, Kurnit KC, Djordjevic B, Singh C, Munsell MF, Wang WL, Lazar AJ, Zhang W, Broaddus R. Nuclear ß-catenin localization and mutation of the CTNNB1 gene: a context-dependent association. Mod Pathol. 2018 10; 31(10):1553-1559.
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Michalova K, Michal M, Sedivcova M, Kazakov DV, Bacchi C, Antic T, Miesbauerova M, Hes O, Michal M. Solid pseudopapillary neoplasm (SPN) of the testis: Comprehensive mutational analysis of 6 testicular and 8 pancreatic SPNs. Ann Diagn Pathol. 2018 Aug; 35:42-47.
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Jiang Y, Ren W, Wang W, Xia J, Gou L, Liu M, Wan Q, Zhou L, Weng Y, He T, Zhang Y. Inhibitor of ß-catenin and TCF (ICAT) promotes cervical cancer growth and metastasis by disrupting E-cadherin/ß-catenin complex. Oncol Rep. 2017 Nov; 38(5):2597-2606.
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Zhang T, Hsu FN, Xie XJ, Li X, Liu M, Gao X, Pei X, Liao Y, Du W, Ji JY. Reversal of hyperactive Wnt signaling-dependent adipocyte defects by peptide boronic acids. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):E7469-E7478.
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Michalova K, Michal M, Kazakov DV, Sedivcova M, Hes O, Hadravsky L, Agaimy A, Tretiakova M, Bacchi C, Hartmann A, Kuroda N, Bulimbasic S, Coric M, Antic T, Michal M. Primary signet ring stromal tumor of the testis: a study of 13 cases indicating their phenotypic and genotypic analogy to pancreatic solid pseudopapillary neoplasm. Hum Pathol. 2017 09; 67:85-93.
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Bhagat TD, Chen S, Bartenstein M, Barlowe AT, Von Ahrens D, Choudhary GS, Tivnan P, Amin E, Marcondes AM, Sanders MA, Hoogenboezem RM, Kambhampati S, Ramachandra N, Mantzaris I, Sukrithan V, Laurence R, Lopez R, Bhagat P, Giricz O, Sohal D, Wickrema A, Yeung C, Gritsman K, Aplan P, Hochedlinger K, Yu Y, Pradhan K, Zhang J, Greally JM, Mukherjee S, Pellagatti A, Boultwood J, Will B, Steidl U, Raaijmakers MHGP, Deeg HJ, Kharas MG, Verma A. Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/ß-Catenin Activation. Cancer Res. 2017 09 15; 77(18):4846-4857.
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Zhang ZC, Liu JX, Shao ZW, Pu FF, Wang BC, Wu Q, Zhang YK, Zeng XL, Guo XD, Yang SH, He TC. In vitro effect of microRNA-107 targeting Dkk-1 by regulation of Wnt/ß-catenin signaling pathway in osteosarcoma. Medicine (Baltimore). 2017 Jul; 96(27):e7245.
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