"Fas Ligand Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
|Fas Ligand Protein
- Fas Ligand Protein
- Fas Ligand (FasL)
- FasL Protein
- TNF Superfamily, Member 6
- CD178 Antigen
- Antigen, CD178
- Antigens, CD178
- Fas Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 6
- CD178 Antigens
- CD95 Antigen Ligand
- CD95 Ligand
Below are MeSH descriptors whose meaning is more general than "Fas Ligand Protein".
Below are MeSH descriptors whose meaning is more specific than "Fas Ligand Protein".
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Below are the most recent publications written about "Fas Ligand Protein" by people in Profiles.
T cells instruct myeloid cells to produce inflammasome-independent IL-1? and cause autoimmunity. Nat Immunol. 2020 01; 21(1):65-74.
Interleukin 22 prevents lipopolysaccharide- induced preterm labor in mice. Biol Reprod. 2018 03 01; 98(3):299-308.
Evaluation of circulating markers of hepatic apoptosis and inflammation in obese children with and without obstructive sleep apnea. Sleep Med. 2015 Sep; 16(9):1031-5.
The role of CD95 and CD95 ligand in cancer. Cell Death Differ. 2015 Apr; 22(4):549-59.
CD95 and CD95L promote and protect cancer stem cells. Nat Commun. 2014 Nov 04; 5:5238.
Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Nat Med. 2014 Jun; 20(6):607-15.
Death induced by CD95 or CD95 ligand elimination. Cell Rep. 2014 Apr 10; 7(1):208-22.
Alkaloids from beach spider lily (Hymenocallis littoralis) induce apoptosis of HepG-2 cells by the fas-signaling pathway. Asian Pac J Cancer Prev. 2014; 15(21):9319-25.
Intestinal epithelial apoptosis initiates gut mucosal injury during extracorporeal membrane oxygenation in the newborn piglet. Lab Invest. 2014 Feb; 94(2):150-60.
Invited commentary. Ann Thorac Surg. 2013 Feb; 95(2):418-9.