 14-3-3 Proteins
"14-3-3 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding proteins involved in important cellular processes including SIGNAL TRANSDUCTION; CELL CYCLE control; APOPTOSIS; and cellular stress responses. 14-3-3 proteins function by interacting with other signal-transducing proteins and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the proteins.
| Descriptor ID |
D048948
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| MeSH Number(s) |
D12.644.360.024.313 D12.776.157.057.126 D12.776.476.024.406
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| Concept/Terms |
14-3-3 Proteins- 14-3-3 Proteins
- 14 3 3 Proteins
- Brain 14-3-3 Protein
- 14-3-3 Protein, Brain
- Brain 14 3 3 Protein
- Protein 14-3-3
- 14-3-3 Protein
- 14 3 3 Protein
14-3-3 Protein, epsilon Isoform- 14-3-3 Protein, epsilon Isoform
- 14 3 3 Protein, epsilon Isoform
- 14-3-3epsilon Protein
- 14 3 3epsilon Protein
- 14-3-3 epsilon Protein
- 14 3 3 epsilon Protein
14-3-3 Protein, zeta Isoform- 14-3-3 Protein, zeta Isoform
- 14 3 3 Protein, zeta Isoform
- 14-3-3zeta Protein
- 14 3 3zeta Protein
- 14-3-3 zeta Protein
- 14 3 3 zeta Protein
14-3-3 Protein, gamma Isoform- 14-3-3 Protein, gamma Isoform
- 14 3 3 Protein, gamma Isoform
- 14-3-3gamma Protein
- 14 3 3gamma Protein
- 14-3-3 gamma Protein
- 14 3 3 gamma Protein
14-3-3 Protein, tau Isoform- 14-3-3 Protein, tau Isoform
- 14 3 3 Protein, tau Isoform
- 14-3-3tau Protein
- 14 3 3tau Protein
- Protein, 14-3-3tau
- 14-3-3 tau Protein
- 14 3 3 tau Protein
14-3-3 Protein, beta Isoform- 14-3-3 Protein, beta Isoform
- 14 3 3 Protein, beta Isoform
- 14-3-3beta Protein
- 14 3 3beta Protein
- 14-3-3 beta Protein
- 14 3 3 beta Protein
14-3-3 Protein, eta Isoform- 14-3-3 Protein, eta Isoform
- 14 3 3 Protein, eta Isoform
- 14-3-3eta Protein
- 14 3 3eta Protein
- 14-3-3 eta Protein
- 14 3 3 eta Protein
- eta Protein, 14-3-3
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Below are MeSH descriptors whose meaning is more general than "14-3-3 Proteins".
Below are MeSH descriptors whose meaning is more specific than "14-3-3 Proteins".
This graph shows the total number of publications written about "14-3-3 Proteins" by people in this website by year, and whether "14-3-3 Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "14-3-3 Proteins" by people in Profiles.
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Riedl W, Acharya D, Lee JH, Liu G, Serman T, Chiang C, Chan YK, Diamond MS, Gack MU. Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity. Cell Host Microbe. 2019 10 09; 26(4):493-503.e6.
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Feng J, Zhang Q, Li C, Zhou Y, Zhao S, Hong L, Song Q, Yu S, Hu C, Wang H, Mao C, Shepard MJ, Hao S, Dominah G, Sun M, Wan H, Park DM, Gilbert MR, Xu G, Zhuang Z, Zhang Y. Enhancement of mitochondrial biogenesis and paradoxical inhibition of lactate dehydrogenase mediated by 14-3-3? in oncocytomas. J Pathol. 2018 07; 245(3):361-372.
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Chan YK, Gack MU. A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity. Nat Immunol. 2016 May; 17(5):523-30.
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Curry CJ, Rosenfeld JA, Grant E, Gripp KW, Anderson C, Aylsworth AS, Saad TB, Chizhikov VV, Dybose G, Fagerberg C, Falco M, Fels C, Fichera M, Graakjaer J, Greco D, Hair J, Hopkins E, Huggins M, Ladda R, Li C, Moeschler J, Nowaczyk MJ, Ozmore JR, Reitano S, Romano C, Roos L, Schnur RE, Sell S, Suwannarat P, Svaneby D, Szybowska M, Tarnopolsky M, Tervo R, Tsai AC, Tucker M, Vallee S, Wheeler FC, Zand DJ, Barkovich AJ, Aradhya S, Shaffer LG, Dobyns WB. The duplication 17p13.3 phenotype: analysis of 21 families delineates developmental, behavioral and brain abnormalities, and rare variant phenotypes. . 2013 Aug; 161A(8):1833-52.
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Grover D, Verma R, Goes FS, Mahon PL, Gershon ES, McMahon FJ, Potash JB. Family-based association of YWHAH in psychotic bipolar disorder. . 2009 Oct 05; 150B(7):977-83.
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Kobayashi R, Deavers M, Patenia R, Rice-Stitt T, Halbe J, Gallardo S, Freedman RS. 14-3-3 zeta protein secreted by tumor associated monocytes/macrophages from ascites of epithelial ovarian cancer patients. Cancer Immunol Immunother. 2009 Feb; 58(2):247-58.
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Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ. How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol. 2007 Nov; 14(11):1025-1040.
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Rosner M, Hengstschläger M. 14-3-3 proteins are involved in the regulation of mammalian cell proliferation. Amino Acids. 2006 Feb; 30(1):105-9.
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Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A. 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul; 34(3):274-85.
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Kato M, Dobyns WB. Lissencephaly and the molecular basis of neuronal migration. Hum Mol Genet. 2003 Apr 01; 12 Spec No 1:R89-96.
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