 ADAM Proteins
"ADAM Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.
| Descriptor ID |
D051722
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| MeSH Number(s) |
D08.811.277.656.675.374.102 D09.400.430.500 D12.776.395.033
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| Concept/Terms |
ADAM Proteins- ADAM Proteins
- A Disintegrin and Metalloprotease Proteins
- ADAM (A Disintegrin and Metalloprotease) Proteins
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Below are MeSH descriptors whose meaning is more general than "ADAM Proteins".
Below are MeSH descriptors whose meaning is more specific than "ADAM Proteins".
This graph shows the total number of publications written about "ADAM Proteins" by people in this website by year, and whether "ADAM Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2006 | 2 | 0 | 2 | | 2009 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "ADAM Proteins" by people in Profiles.
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Zhou Z, Tang AT, Wong WY, Bamezai S, Goddard LM, Shenkar R, Zhou S, Yang J, Wright AC, Foley M, Arthur JS, Whitehead KJ, Awad IA, Li DY, Zheng X, Kahn ML. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. 2016 Apr 07; 532(7597):122-6.
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Barreto-Luis A, Pino-Yanes M, Corrales A, Campo P, Callero A, Acosta-Herrera M, Cumplido J, Ma SF, Martinez-Tadeo J, Villar J, Garcia JG, Carrillo T, Carracedo Á, Blanca M, Flores C. Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene. J Allergy Clin Immunol. 2016 Mar; 137(3):964-6.
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Mezyk-Kopec R, Wyroba B, Stalinska K, Próchnicki T, Wiatrowska K, Kilarski WW, Swartz MA, Bereta J. ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells. PLoS One. 2015; 10(7):e0132661.
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Powers ME, Becker RE, Sailer A, Turner JR, Bubeck Wardenburg J. Synergistic Action of Staphylococcus aureus a-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis. . 2015 Jun 10; 17(6):775-87.
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Feng Z, Jia X, Adams MD, Ghosh SK, Bonomo RA, Weinberg A. Epithelial innate immune response to Acinetobacter baumannii challenge. Infect Immun. 2014 Nov; 82(11):4458-65.
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Greene AC, Lord SJ, Tian A, Rhodes C, Kai H, Groves JT. Spatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1. Biophys J. 2014 May 20; 106(10):2196-205.
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Becker RE, Berube BJ, Sampedro GR, DeDent AC, Bubeck Wardenburg J. Tissue-specific patterning of host innate immune responses by Staphylococcus aureus a-toxin. J Innate Immun. 2014; 6(5):619-31.
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Das S, Czarnek M, Bzowska M, Mezyk-Kopec R, Stalinska K, Wyroba B, Sroka J, Jucha J, Deneka D, Stoklosa P, Ogonek J, Swartz MA, Madeja Z, Bereta J. ADAM17 silencing in mouse colon carcinoma cells: the effect on tumoricidal cytokines and angiogenesis. PLoS One. 2012; 7(12):e50791.
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Powers ME, Kim HK, Wang Y, Bubeck Wardenburg J. ADAM10 mediates vascular injury induced by Staphylococcus aureus a-hemolysin. J Infect Dis. 2012 Aug 01; 206(3):352-6.
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Inoshima N, Wang Y, Bubeck Wardenburg J. Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection. J Invest Dermatol. 2012 May; 132(5):1513-6.
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