Signaling Lymphocytic Activation Molecule Associated Protein
"Signaling Lymphocytic Activation Molecule Associated Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing adaptor protein that contains a single SH2 DOMAIN and is essential for the regulation of SLAM FAMILY RECEPTORS in the immune response. Mutations in the SLAM-associated protein gene have been identified in cases of X-LINKED LYMPHOPROLIFERATIVE DISEASE.
| Descriptor ID |
D000071179
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| MeSH Number(s) |
D12.644.360.024.332 D12.776.157.057.166 D12.776.476.024.426
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Signaling Lymphocytic Activation Molecule Associated Protein".
Below are MeSH descriptors whose meaning is more specific than "Signaling Lymphocytic Activation Molecule Associated Protein".
This graph shows the total number of publications written about "Signaling Lymphocytic Activation Molecule Associated Protein" by people in this website by year, and whether "Signaling Lymphocytic Activation Molecule Associated Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
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Below are the most recent publications written about "Signaling Lymphocytic Activation Molecule Associated Protein" by people in Profiles.
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SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics. Immunity. 2010 Aug 27; 33(2):203-15.
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Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent "innate" gammadelta T cells. PLoS One. 2010 Feb 19; 5(2):e9303.
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The My(c)stery of iNKT cell ontogeny. Cell Cycle. 2009 Oct 01; 8(19):3082-5.
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Molecular basis of the dual functions of 2B4 (CD244). J Immunol. 2008 Jun 15; 180(12):8159-67.
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Signaling for NKT cell development: the SAP-FynT connection. J Exp Med. 2005 Mar 21; 201(6):833-6.