"Homeobox Protein Nkx-2.5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL DEFECTS and TETRALOGY OF FALLOT.
|Homeobox Protein Nkx-2.5
- Homeobox Protein Nkx-2.5
- Homeobox Protein Nkx 2.5
- Nkx-2.5, Homeobox Protein
- NK2 Homeobox 5 Protein
- Homeobox Transcription Factor Csx-Nkx2-5
- Homeobox Transcription Factor Csx Nkx2 5
- Homeobox Protein Csx-Nkx2.5
- Csx-Nkx2.5, Homeobox Protein
- Homeobox Protein Csx Nkx2.5
- Cardiac-Specific Homeobox Protein
- Cardiac Specific Homeobox Protein
- Homeobox Protein, Cardiac-Specific
- Transcription Factor Nkx-2.5
- Nkx-2.5, Transcription Factor
- Transcription Factor Nkx 2.5
Below are MeSH descriptors whose meaning is more general than "Homeobox Protein Nkx-2.5".
Below are MeSH descriptors whose meaning is more specific than "Homeobox Protein Nkx-2.5".
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Below are the most recent publications written about "Homeobox Protein Nkx-2.5" by people in Profiles.
Noncanonical Notch signals have opposing roles during cardiac development. Biochem Biophys Res Commun. 2021 11 05; 577:12-16.
Transcription factor ETV1 is essential for rapid conduction in the heart. J Clin Invest. 2016 12 01; 126(12):4444-4459.
Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):E2020-9.
Complex trait analysis of ventricular septal defects caused by Nkx2-5 mutation. Circ Cardiovasc Genet. 2012 Jun; 5(3):293-300.
Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar; 52(3):638-49.
Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects. PLoS One. 2011; 6(6):e20803.
Mutations in the NKX2.5 gene and the PAX8 promoter in a girl with thyroid dysgenesis. J Clin Endocrinol Metab. 2011 Jun; 96(6):E977-81.
Characterization and functionality of cardiac progenitor cells in congenital heart patients. Circulation. 2011 Feb 01; 123(4):364-73.
Heterogeneity of genetic modifiers ensures normal cardiac development. Circulation. 2010 Mar 23; 121(11):1313-21.
A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population. J Hum Genet. 2008; 53(2):151-162.