Myeloid Ecotropic Viral Integration Site 1 Protein
"Myeloid Ecotropic Viral Integration Site 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TALE-type homeodomain protein and transcription factor that functions as a regulator of PAX6 PROTEIN expression and as an activator of PLATELET FACTOR 4 gene expression. It is essential for hematopoiesis, differentiation of MEGAKARYOCYTES, and vascular patterning. It may also have a role in the induction of myeloid leukemias.
| Descriptor ID |
D000075064
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| MeSH Number(s) |
D12.776.260.400.483 D12.776.930.462
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myeloid Ecotropic Viral Integration Site 1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Myeloid Ecotropic Viral Integration Site 1 Protein".
This graph shows the total number of publications written about "Myeloid Ecotropic Viral Integration Site 1 Protein" by people in this website by year, and whether "Myeloid Ecotropic Viral Integration Site 1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 4 | 4 |
| 2013 | 0 | 3 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Myeloid Ecotropic Viral Integration Site 1 Protein" by people in Profiles.
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Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia. Elife. 2021 07 15; 10.
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Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts. Mod Pathol. 2021 06; 34(6):1203-1212.
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MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease. Clin Cancer Res. 2018 08 01; 24(15):3668-3680.
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PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease. Cancer Res. 2016 Feb 01; 76(3):619-29.
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Hif-1a and Hif-2a synergize to suppress AML development but are dispensable for disease maintenance. J Exp Med. 2015 Dec 14; 212(13):2223-34.
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Hoxa2 selectively enhances Meis binding to change a branchial arch ground state. Dev Cell. 2015 Feb 09; 32(3):265-77.
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PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway. Leukemia. 2014 Jul; 28(7):1436-48.
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Regulation of MEIS1 by distal enhancer elements in acute leukemia. Leukemia. 2014 Jan; 28(1):138-46.
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TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11994-9.
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MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19397-402.