alpha 1-Antichymotrypsin
"alpha 1-Antichymotrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoprotein found in alpha(1)-globulin region in human serum. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. It is a member of the serpin superfamily.
Descriptor ID |
D000514
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MeSH Number(s) |
D12.644.822.750.030 D12.644.861.030 D12.776.124.050.050 D12.776.124.790.106.050 D12.776.377.715.085.050 D12.776.395.045 D12.776.645.750.030 D12.776.872.030
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "alpha 1-Antichymotrypsin".
Below are MeSH descriptors whose meaning is more specific than "alpha 1-Antichymotrypsin".
This graph shows the total number of publications written about "alpha 1-Antichymotrypsin" by people in this website by year, and whether "alpha 1-Antichymotrypsin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1988 | 1 | 0 | 1 | 1991 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "alpha 1-Antichymotrypsin" by people in Profiles.
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Roberts AS, Campa MJ, Gottlin EB, Jiang C, Owzar K, Kindler HL, Venook AP, Goldberg RM, O'Reilly EM, Patz EF. Identification of potential prognostic biomarkers in patients with untreated, advanced pancreatic cancer from a phase 3 trial (Cancer and Leukemia Group B 80303). Cancer. 2012 Jan 15; 118(2):571-8.
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Nakamura S, Kiatipattanasakul W, Nakayama H, Ono F, Sakakibara I, Yoshikawa Y, Goto N, Doi K. Immunohistochemical characteristics of the constituents of senile plaques and amyloid angiopathy in aged cynomolgus monkeys. J Med Primatol. 1996 Aug; 25(4):294-300.
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Abraham CR, Razzaboni BL, Sisodia SS, Koo EH, Price DL, Van Nostrand WE, Papastoitsis G. Studies on the proteolytic degradation of the beta-protein precursor by proteases purified from Alzheimer's disease brain. Ann N Y Acad Sci. 1991; 640:161-5.
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Kanellaki-Kyparissi M, Krausz T, Wigglesworth J, Van Noorden S. [Localization of protease inhibitors in the chorionic villi of the human placenta, by means of the immunoperoxidase technic]. Bull Assoc Anat (Nancy). 1988 Jun-Sep; 72(217-218):21-5.
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