Plasminogen Activators
"Plasminogen Activators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.
Descriptor ID |
D010960
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MeSH Number(s) |
D08.811.277.656.300.760.635 D08.811.277.656.959.350.635 D12.776.124.125.662
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Plasminogen Activators".
Below are MeSH descriptors whose meaning is more specific than "Plasminogen Activators".
This graph shows the total number of publications written about "Plasminogen Activators" by people in this website by year, and whether "Plasminogen Activators" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1986 | 1 | 0 | 1 | 1989 | 1 | 0 | 1 | 1996 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 | 1998 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2000 | 1 | 0 | 1 | 2001 | 2 | 0 | 2 | 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Plasminogen Activators" by people in Profiles.
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Dafer RM, Biller J. Desmoteplase in the treatment of acute ischemic stroke. Expert Rev Neurother. 2007 Apr; 7(4):333-7.
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Svoboda P, Barton RP, Barbarash OL, Butylin AA, Jacobs BR, Lata J, Haire WD, Jaff MR, Firszt CM, Mouginis TL, Schuerr DM, Schulz GA, Schwartz LB, El-Shahawy MA. Recombinant urokinase is safe and effective in restoring patency to occluded central venous access devices: a multiple-center, international trial. Crit Care Med. 2004 Oct; 32(10):1990-6.
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Mauceri HJ, Seetharam S, Beckett MA, Lee JY, Gupta VK, Gately S, Stack MS, Brown CK, Swedberg K, Kufe DW, Weichselbaum RR. Tumor production of angiostatin is enhanced after exposure to TNF-alpha. Int J Cancer. 2002 Feb 01; 97(4):410-5.
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Duda SH, Tepe G, Bala M, Luz O, Ziemer G, Ouriel K, Pusich B, Wiskirchen J, Claussen CD, Banz K. Economic value of thrombolysis with adjunctive abciximab in patients with subacute peripheral arterial occlusion. Pharmacoeconomics. 2002; 20(3):203-13.
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Duda SH, Tepe G, Luz O, Ouriel K, Dietz K, Hahn U, Pereira P, Marsalek P, Ziemer G, Erley CM, Claussen CD. Peripheral artery occlusion: treatment with abciximab plus urokinase versus with urokinase alone--a randomized pilot trial (the PROMPT Study). Platelet Receptor Antibodies in Order to Manage Peripheral Artery Thrombosis. Radiology. 2001 Dec; 221(3):689-96.
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Framme C, Spiegel D, Roider J, Sachs HG, Lohmann CP, Butz B, Link J, Gabel VP. [Central retinal artery occlusion. Importance of selective intra-arterial fibrinolysis]. Ophthalmologe. 2001 Aug; 98(8):725-30.
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Sazonova IY, Houng AK, Chowdhry SA, Robinson BR, Hedstrom L, Reed GL. The mechanism of a bacterial plasminogen activator intermediate between streptokinase and staphylokinase. J Biol Chem. 2001 Apr 20; 276(16):12609-13.
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Montes JM, Wong JH, Fayad PB, Awad IA. Stereotactic computed tomographic-guided aspiration and thrombolysis of intracerebral hematoma : protocol and preliminary experience. Stroke. 2000 Apr; 31(4):834-40.
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Frank JI. Contemporary acute ischemic stroke therapy with intravenous recombinant tissue plasminogen activator. Clin Neurosurg. 2000; 46:261-6.
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Zaleski GX, Funaki B, Kenney S, Lorenz JM, Garofalo R. Angioplasty and bolus urokinase infusion for the restoration of function in thrombosed Brescia-Cimino dialysis fistulas. J Vasc Interv Radiol. 1999 Feb; 10(2 Pt 1):129-36.
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