 Transferrin
"Transferrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An iron-binding beta1-globulin that is synthesized in the LIVER and secreted into the blood. It plays a central role in the transport of IRON throughout the circulation. A variety of transferrin isoforms exist in humans, including some that are considered markers for specific disease states.
| Descriptor ID |
D014168
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| MeSH Number(s) |
D12.776.124.050.800 D12.776.124.790.223.839 D12.776.157.427.750.500 D12.776.377.715.182.839 D12.776.556.579.750.500
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| Concept/Terms |
Transferrin- Transferrin
- Serotransferrin
- Siderophilin
- beta-1 Metal-Binding Globulin
- Globulin, beta-1 Metal-Binding
- Metal-Binding Globulin, beta-1
- beta 1 Metal Binding Globulin
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Below are MeSH descriptors whose meaning is more general than "Transferrin".
Below are MeSH descriptors whose meaning is more specific than "Transferrin".
This graph shows the total number of publications written about "Transferrin" by people in this website by year, and whether "Transferrin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1987 | 0 | 1 | 1 | | 1988 | 2 | 0 | 2 | | 1989 | 2 | 0 | 2 | | 1994 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2011 | 2 | 1 | 3 | | 2014 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transferrin" by people in Profiles.
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Osei-Owusu J, Yang J, Leung KH, Ruan Z, Lü W, Krishnan Y, Qiu Z. Proton-activated chloride channel PAC regulates endosomal acidification and transferrin receptor-mediated endocytosis. Cell Rep. 2021 01 26; 34(4):108683.
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Banerjee A, Grazon C, Pons T, Bhatia D, Valades-Cruz CA, Johannes L, Krishnan Y, Dubertret B. A novel type of quantum dot-transferrin conjugate using DNA hybridization mimics intracellular recycling of endogenous transferrin. Nanoscale. 2017 Oct 19; 9(40):15453-15460.
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Haldar S, Tripathi A, Qian J, Beserra A, Suda S, McElwee M, Turner J, Hopfer U, Singh N. Prion protein promotes kidney iron uptake via its ferrireductase activity. J Biol Chem. 2015 Feb 27; 290(9):5512-22.
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Peerschke EI, Pessin MS, Maslak P. Using the hemoglobin content of reticulocytes (RET-He) to evaluate anemia in patients with cancer. Am J Clin Pathol. 2014 Oct; 142(4):506-12.
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Chang J, Paillard A, Passirani C, Morille M, Benoit JP, Betbeder D, Garcion E. Transferrin adsorption onto PLGA nanoparticles governs their interaction with biological systems from blood circulation to brain cancer cells. Pharm Res. 2012 Jun; 29(6):1495-505.
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Bourseau-Guilmain E, Griveau A, Benoit JP, Garcion E. The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells. PLoS One. 2011; 6(9):e25515.
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Miyata S, Kawabata S, Hiramatsu R, Doi A, Ikeda N, Yamashita T, Kuroiwa T, Kasaoka S, Maruyama K, Miyatake S. Computed tomography imaging of transferrin targeting liposomes encapsulating both boron and iodine contrast agents by convection-enhanced delivery to F98 rat glioma for boron neutron capture therapy. Neurosurgery. 2011 May; 68(5):1380-7; discussion 1387.
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Suzuki M, Wiers K, Brooks EB, Greis KD, Haines K, Klein-Gitelman MS, Olson J, Onel K, O'Neil KM, Silverman ED, Tucker L, Ying J, Devarajan P, Brunner HI. Initial validation of a novel protein biomarker panel for active pediatric lupus nephritis. Pediatr Res. 2009 May; 65(5):530-6.
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Doherty KR, Demonbreun AR, Wallace GQ, Cave A, Posey AD, Heretis K, Pytel P, McNally EM. The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion. J Biol Chem. 2008 Jul 18; 283(29):20252-60.
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Doi A, Kawabata S, Iida K, Yokoyama K, Kajimoto Y, Kuroiwa T, Shirakawa T, Kirihata M, Kasaoka S, Maruyama K, Kumada H, Sakurai Y, Masunaga S, Ono K, Miyatake S. Tumor-specific targeting of sodium borocaptate (BSH) to malignant glioma by transferrin-PEG liposomes: a modality for boron neutron capture therapy. J Neurooncol. 2008 May; 87(3):287-94.
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