Mitogen-Activated Protein Kinases
"Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
| Descriptor ID |
D020928
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567 D12.644.360.450 D12.776.476.450
|
| Concept/Terms |
Mitogen-Activated Protein Kinases- Mitogen-Activated Protein Kinases
- Kinases, Mitogen-Activated Protein
- Mitogen Activated Protein Kinases
- Protein Kinases, Mitogen-Activated
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinases" by people in this website by year, and whether "Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 5 | 0 | 5 |
| 1997 | 4 | 0 | 4 |
| 1998 | 4 | 0 | 4 |
| 1999 | 9 | 3 | 12 |
| 2000 | 7 | 10 | 17 |
| 2001 | 15 | 6 | 21 |
| 2002 | 7 | 14 | 21 |
| 2003 | 7 | 14 | 21 |
| 2004 | 7 | 6 | 13 |
| 2005 | 4 | 3 | 7 |
| 2006 | 1 | 4 | 5 |
| 2007 | 1 | 2 | 3 |
| 2008 | 3 | 5 | 8 |
| 2009 | 0 | 3 | 3 |
| 2010 | 4 | 2 | 6 |
| 2011 | 1 | 4 | 5 |
| 2012 | 2 | 4 | 6 |
| 2013 | 4 | 1 | 5 |
| 2014 | 2 | 4 | 6 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinases" by people in Profiles.
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Diffuse astrocytoma, AYA-type, frequently MAPK-altered: report of 45 patients. Acta Neuropathol. 2025 Apr 09; 149(1):32.
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Phytosulfokine downregulates defense-related WRKY transcription factors and attenuates pathogen-associated molecular pattern-triggered immunity. Plant J. 2024 Dec; 120(6):2367-2384.
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H1N1 Influenza Virus Cross-Activates Gli1 to Disrupt the Intercellular Junctions of Alveolar Epithelial Cells. Cell Rep. 2020 06 30; 31(13):107801.
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Controlled release of bioactive signaling molecules. Methods Enzymol. 2020; 638:129-138.
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Multi-kinase control of environmental stress responsive transcription. PLoS One. 2020; 15(3):e0230246.
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Role of TGF-ß-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication. Virology. 2019 11; 537:263-271.
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Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer. Cell. 2019 06 27; 178(1):160-175.e27.
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RET rearrangements are actionable alterations in breast cancer. Nat Commun. 2018 11 16; 9(1):4821.
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Engineering allosteric regulation in protein kinases. Sci Signal. 2018 11 06; 11(555).
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Identification and Targeting of Kinase Alterations in Histiocytic Neoplasms. Hematol Oncol Clin North Am. 2017 08; 31(4):705-719.