 Mitogen-Activated Protein Kinases
"Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
| Descriptor ID |
D020928
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567 D08.811.913.696.620.682.700.646.750 D12.644.360.450 D12.776.476.450
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| Concept/Terms |
Mitogen-Activated Protein Kinases- Mitogen-Activated Protein Kinases
- Kinases, Mitogen-Activated Protein
- Mitogen Activated Protein Kinases
- Protein Kinases, Mitogen-Activated
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinases" by people in this website by year, and whether "Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 2 | 0 | 2 | | 1996 | 5 | 0 | 5 | | 1997 | 4 | 0 | 4 | | 1998 | 4 | 0 | 4 | | 1999 | 8 | 3 | 11 | | 2000 | 7 | 10 | 17 | | 2001 | 15 | 6 | 21 | | 2002 | 8 | 14 | 22 | | 2003 | 8 | 11 | 19 | | 2004 | 8 | 6 | 14 | | 2005 | 4 | 3 | 7 | | 2006 | 1 | 5 | 6 | | 2007 | 1 | 2 | 3 | | 2008 | 3 | 5 | 8 | | 2009 | 0 | 4 | 4 | | 2010 | 3 | 2 | 5 | | 2011 | 1 | 4 | 5 | | 2012 | 2 | 4 | 6 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 3 | 4 | | 2015 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinases" by people in Profiles.
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Pincus D, Pandey JP, Feder ZA, Creixell P, Resnekov O, Reynolds KA. Engineering allosteric regulation in protein kinases. Sci Signal. 2018 11 06; 11(555).
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Hong Q, Ma ZC, Huang H, Wang YG, Tan HL, Xiao CR, Liang QD, Zhang HT, Gao Y. Antithrombotic activities of ferulic acid via intracellular cyclic nucleotide signaling. Eur J Pharmacol. 2016 Apr 15; 777:1-8.
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Ghio AJ, Soukup JM, Dailey LA, Tong H, Kesic MJ, Budinger GR, Mutlu GM. Wood Smoke Particle Sequesters Cell Iron to Impact a Biological Effect. Chem Res Toxicol. 2015 Nov 16; 28(11):2104-11.
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Yuan J, Guo J, Zhang M, Wang Q, Huang H, Chen Y. Upregulation of D site of albumin promoter binding protein in the brain of patients with intractable epilepsy. Mol Med Rep. 2015 Apr; 11(4):2486-92.
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Li J, Fettiplace M, Chen SJ, Steinhorn B, Shao Z, Zhu X, Li C, Harty S, Weinberg G, Vanden Hoek TL. Lipid emulsion rapidly restores contractility in stunned mouse cardiomyocytes: a comparison with therapeutic hypothermia. Crit Care Med. 2014 Dec; 42(12):e734-40.
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Mull A, Kim G, Holaska JM. LMO7-null mice exhibit phenotypes consistent with emery-dreifuss muscular dystrophy. Muscle Nerve. 2015 Feb; 51(2):222-8.
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Tateda C, Zhang Z, Shrestha J, Jelenska J, Chinchilla D, Greenberg JT. Salicylic acid regulates Arabidopsis microbial pattern receptor kinase levels and signaling. Plant Cell. 2014 Oct; 26(10):4171-87.
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Lifshitz Z, Burstein D, Schwartz K, Shuman HA, Pupko T, Segal G. Identification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway. Infect Immun. 2014 Sep; 82(9):3740-52.
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Zhang W, Zhang H, Wang N, Zhao C, Zhang H, Deng F, Wu N, He Y, Chen X, Zhang J, Wen S, Liao Z, Zhang Q, Zhang Z, Liu W, Yan Z, Luu HH, Haydon RC, Zhou L, He TC. Modulation of ß-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci. 2013; 10(13):1888-98.
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Ha J, Kim HJ, Huang H, Lee ZH, Kim HH. Mitogen- and stress-activated protein kinase 1 activates osteoclastogenesis in vitro and affects bone destruction in vivo. J Mol Med (Berl). 2013 Aug; 91(8):977-87.
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