 Mitogen-Activated Protein Kinases
"Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
| Descriptor ID |
D020928
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567 D08.811.913.696.620.682.700.646.750 D12.644.360.450 D12.776.476.450
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| Concept/Terms |
Mitogen-Activated Protein Kinases- Mitogen-Activated Protein Kinases
- Kinases, Mitogen-Activated Protein
- Mitogen Activated Protein Kinases
- Protein Kinases, Mitogen-Activated
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinases" by people in this website by year, and whether "Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1995 | 2 | 0 | 2 | | 1996 | 5 | 0 | 5 | | 1997 | 4 | 0 | 4 | | 1998 | 4 | 0 | 4 | | 1999 | 8 | 3 | 11 | | 2000 | 7 | 10 | 17 | | 2001 | 15 | 6 | 21 | | 2002 | 8 | 14 | 22 | | 2003 | 8 | 14 | 22 | | 2004 | 8 | 6 | 14 | | 2005 | 4 | 3 | 7 | | 2006 | 1 | 5 | 6 | | 2007 | 1 | 2 | 3 | | 2008 | 3 | 5 | 8 | | 2009 | 0 | 3 | 3 | | 2010 | 4 | 2 | 6 | | 2011 | 1 | 4 | 5 | | 2012 | 2 | 4 | 6 | | 2013 | 4 | 1 | 5 | | 2014 | 2 | 4 | 6 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2018 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 0 | 3 | 3 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinases" by people in Profiles.
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Ruan T, Sun J, Liu W, Prinz RA, Peng D, Liu X, Xu X. H1N1 Influenza Virus Cross-Activates Gli1 to Disrupt the Intercellular Junctions of Alveolar Epithelial Cells. Cell Rep. 2020 06 30; 31(13):107801.
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Jani MS, Veetil AT, Krishnan Y. Controlled release of bioactive signaling molecules. Methods Enzymol. 2020; 638:129-138.
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Mace K, Krakowiak J, El-Samad H, Pincus D. Multi-kinase control of environmental stress responsive transcription. PLoS One. 2020; 15(3):e0230246.
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Sheng T, Sun Y, Sun J, Prinz RA, Peng D, Liu X, Xu X. Role of TGF-ß-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication. Virology. 2019 11; 537:263-271.
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Paratala BS, Chung JH, Williams CB, Yilmazel B, Petrosky W, Williams K, Schrock AB, Gay LM, Lee E, Dolfi SC, Pham K, Lin S, Yao M, Kulkarni A, DiClemente F, Liu C, Rodriguez-Rodriguez L, Ganesan S, Ross JS, Ali SM, Leyland-Jones B, Hirshfield KM. RET rearrangements are actionable alterations in breast cancer. Nat Commun. 2018 11 16; 9(1):4821.
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Pincus D, Pandey JP, Feder ZA, Creixell P, Resnekov O, Reynolds KA. Engineering allosteric regulation in protein kinases. Sci Signal. 2018 11 06; 11(555).
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Borahay MA, Asoglu MR, Mas A, Adam S, Kilic GS, Al-Hendy A. Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications. Reprod Sci. 2017 09; 24(9):1235-1244.
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Hong Q, Ma ZC, Huang H, Wang YG, Tan HL, Xiao CR, Liang QD, Zhang HT, Gao Y. Antithrombotic activities of ferulic acid via intracellular cyclic nucleotide signaling. Eur J Pharmacol. 2016 Apr 15; 777:1-8.
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Ghio AJ, Soukup JM, Dailey LA, Tong H, Kesic MJ, Budinger GR, Mutlu GM. Wood Smoke Particle Sequesters Cell Iron to Impact a Biological Effect. Chem Res Toxicol. 2015 Nov 16; 28(11):2104-11.
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Yuan J, Guo J, Zhang M, Wang Q, Huang H, Chen Y. Upregulation of D site of albumin promoter binding protein in the brain of patients with intractable epilepsy. Mol Med Rep. 2015 Apr; 11(4):2486-92.
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