Apoptosis Regulatory Proteins
"Apoptosis Regulatory Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES.
| Descriptor ID |
D051017
|
| MeSH Number(s) |
D12.644.360.075 D12.776.476.075
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Apoptosis Regulatory Proteins".
Below are MeSH descriptors whose meaning is more specific than "Apoptosis Regulatory Proteins".
This graph shows the total number of publications written about "Apoptosis Regulatory Proteins" by people in this website by year, and whether "Apoptosis Regulatory Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 4 | 4 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 5 | 5 |
| 2004 | 0 | 12 | 12 |
| 2005 | 1 | 1 | 2 |
| 2006 | 2 | 4 | 6 |
| 2007 | 4 | 3 | 7 |
| 2008 | 2 | 3 | 5 |
| 2009 | 5 | 5 | 10 |
| 2010 | 5 | 8 | 13 |
| 2011 | 5 | 2 | 7 |
| 2012 | 4 | 1 | 5 |
| 2013 | 2 | 5 | 7 |
| 2014 | 8 | 2 | 10 |
| 2015 | 2 | 5 | 7 |
| 2016 | 1 | 3 | 4 |
| 2018 | 3 | 1 | 4 |
| 2019 | 3 | 2 | 5 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 2 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apoptosis Regulatory Proteins" by people in Profiles.
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Innate Conformational Dynamics Drive Binding Specificity in Anti-Apoptotic Proteins Mcl-1 and Bcl-2. Biochemistry. 2023 06 06; 62(11):1619-1630.
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Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 07 01; 131(13).
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Propranolol inhibits cavernous vascular malformations by ß1 adrenergic receptor antagonism in animal models. J Clin Invest. 2021 02 01; 131(3).
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In vitro and in vivo efficacy of the novel oral proteasome inhibitor NNU546 in multiple myeloma. Aging (Albany NY). 2020 11 16; 12(22):22949-22974.
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Novel Murine Models of Cerebral Cavernous Malformations. Angiogenesis. 2020 11; 23(4):651-666.
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Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. Sci Transl Med. 2019 11 27; 11(520).
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A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease. Transl Stroke Res. 2020 06; 11(3):365-376.
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Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations. Acta Neuropathol Commun. 2019 08 19; 7(1):132.
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A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Nat Commun. 2019 04 17; 10(1):1791.
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Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease. Stroke. 2019 03; 50(3):738-744.