 3',5'-Cyclic-AMP Phosphodiesterases
"3',5'-Cyclic-AMP Phosphodiesterases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the hydrolysis of CYCLIC AMP to form adenosine 5'-phosphate. The enzymes are widely distributed in animal tissue and control the level of intracellular cyclic AMP. Many specific enzymes classified under this heading demonstrate additional spcificity for 3',5'-cyclic IMP and CYCLIC GMP.
| Descriptor ID |
D015105
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| MeSH Number(s) |
D08.811.277.352.640.150 D12.644.360.008 D12.776.476.008
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| Concept/Terms |
3',5'-Cyclic-AMP Phosphodiesterases- 3',5'-Cyclic-AMP Phosphodiesterases
- 3',5' Cyclic AMP Phosphodiesterases
- Phosphodiesterases, 3',5'-Cyclic-AMP
- 3',5'-Cyclic AMP 5'-Nucleotidohydrolase
- 3',5' Cyclic AMP 5' Nucleotidohydrolase
- 5'-Nucleotidohydrolase, 3',5'-Cyclic AMP
- AMP 5'-Nucleotidohydrolase, 3',5'-Cyclic
- 3',5'-Cyclic AMP Phosphodiesterase
- AMP Phosphodiesterase, 3',5'-Cyclic
- Phosphodiesterase, 3',5'-Cyclic AMP
- 3',5'-Cyclic Nucleotide Phosphodiesterase
- 3',5' Cyclic Nucleotide Phosphodiesterase
- Nucleotide Phosphodiesterase, 3',5'-Cyclic
- Phosphodiesterase, 3',5'-Cyclic Nucleotide
- 3',5'-Cyclic-AMP Phosphodiesterase
- Phosphodiesterase, 3',5'-Cyclic-AMP
- 3',5'-Nucleotide Phosphodiesterase
- 3',5' Nucleotide Phosphodiesterase
- Phosphodiesterase, 3',5'-Nucleotide
- 3,5-Cyclic AMP 5-Nucleotidohydrolase
- 3,5 Cyclic AMP 5 Nucleotidohydrolase
- 5-Nucleotidohydrolase, 3,5-Cyclic AMP
- AMP 5-Nucleotidohydrolase, 3,5-Cyclic
- 3,5-Cyclic AMP Phosphodiesterase
- 3,5 Cyclic AMP Phosphodiesterase
- AMP Phosphodiesterase, 3,5-Cyclic
- Phosphodiesterase, 3,5-Cyclic AMP
- CAMP Phosphodiesterase
- Phosphodiesterase, CAMP
- 3',5' Cyclic AMP Phosphodiesterase
- 3',5'-Cyclic-Nucleotide Phosphodiesterase
- Phosphodiesterase, 3',5'-Cyclic-Nucleotide
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Below are MeSH descriptors whose meaning is more general than "3',5'-Cyclic-AMP Phosphodiesterases".
Below are MeSH descriptors whose meaning is more specific than "3',5'-Cyclic-AMP Phosphodiesterases".
This graph shows the total number of publications written about "3',5'-Cyclic-AMP Phosphodiesterases" by people in this website by year, and whether "3',5'-Cyclic-AMP Phosphodiesterases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2006 | 2 | 2 | 4 | | 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "3',5'-Cyclic-AMP Phosphodiesterases" by people in Profiles.
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Hajjhussein H, Suvarna NU, Gremillion C, Chandler LJ, O'Donnell JM. Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures. Brain Res. 2007 May 29; 1149:58-68.
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Schreiber S, Keshavarzian A, Isaacs KL, Schollenberger J, Guzman JP, Orlandi C, Hanauer SB. A randomized, placebo-controlled, phase II study of tetomilast in active ulcerative colitis. Gastroenterology. 2007 Jan; 132(1):76-86.
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Meliton AY, Muñoz NM, Lambertino A, Boetticher E, Learoyd J, Zhu X, Leff AR. Phosphodiesterase 4 inhibition of beta2-integrin adhesion caused by leukotriene B4 and TNF-alpha in human neutrophils. Eur Respir J. 2006 Nov; 28(5):920-8.
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Kajikawa S, Kigami D, Nakayama H, Doi K. Changes in submaxillary gland gene expression in F344 rats by multiple dosing of theophylline. Exp Anim. 2006 Apr; 55(2):143-6.
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Rennard SI, Schachter N, Strek M, Rickard K, Amit O. Cilomilast for COPD: results of a 6-month, placebo-controlled study of a potent, selective inhibitor of phosphodiesterase 4. Chest. 2006 Jan; 129(1):56-66.
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Pare GC, Easlick JL, Mislow JM, McNally EM, Kapiloff MS. Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelope. Exp Cell Res. 2005 Feb 15; 303(2):388-99.
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Liu J, Muñoz NM, Meliton AY, Zhu X, Lambertino AT, Xu C, Myo S, Myou S, Boetticher E, Johnson M, Leff AR. Beta2-integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and beta2-adrenoceptor activation in human eosinophils. Pulm Pharmacol Ther. 2004; 17(2):73-9.
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Meliton AY, Muñoz NM, Liu J, Lambertino AT, Boetticher E, Myo S, Myou S, Zhu X, Johnson M, Leff AR. Blockade of LTC4 synthesis caused by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils. J Allergy Clin Immunol. 2003 Aug; 112(2):404-10.
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Popko B, Pearl DK, Walker DM, Comas TC, Baerwald KD, Burger PC, Scheithauer BW, Yates AJ. Molecular markers that identify human astrocytomas and oligodendrogliomas. J Neuropathol Exp Neurol. 2002 Apr; 61(4):329-38.
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Hibino N, Tomino T, Satoh H, Hamawaki M, Imura M, Suzuki T, Inukai M. [The effect of milrinone administrated before weaning from cardiopulmonary bypass in adult cardiac surgery]. Kyobu Geka. 2000 Nov; 53(12):1019-23.
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