"Telomerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.
| Descriptor ID |
D019098
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.750.750 D12.776.157.687.613 D12.776.157.725.500.921 D12.776.660.720.613 D12.776.664.962.500.921
|
| Concept/Terms |
Telomerase- Telomerase
- Telomerase Reverse Transcriptase
- Reverse Transcriptase, Telomerase
- Transcriptase, Telomerase Reverse
Telomerase Catalytic Subunit- Telomerase Catalytic Subunit
- Catalytic Subunit, Telomerase
- Subunit, Telomerase Catalytic
- Telomerase Reverse Transcriptase Catalytic Subunit
|
Below are MeSH descriptors whose meaning is more general than "Telomerase".
Below are MeSH descriptors whose meaning is more specific than "Telomerase".
This graph shows the total number of publications written about "Telomerase" by people in this website by year, and whether "Telomerase" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 1 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 3 | 1 | 4 |
| 2014 | 0 | 1 | 1 |
| 2015 | 4 | 0 | 4 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 3 | 3 |
| 2020 | 3 | 1 | 4 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Telomerase" by people in Profiles.
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Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization. Cell Chem Biol. 2022 10 20; 29(10):1517-1531.e7.
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Pediatric Gliomas Presenting with Gliomatosis-Like Spread, Lack of Contrast Enhancement, EGFR Mutation, and TERT Promoter Variants. J Neuropathol Exp Neurol. 2021 12 29; 80(12):1134-1136.
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Randomized, Single-Blind, Multicenter Phase II Study of Two Doses of Imetelstat in Relapsed or Refractory Myelofibrosis. J Clin Oncol. 2021 09 10; 39(26):2881-2892.
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Telomere biology disorder prevalence and phenotypes in adults with familial hematologic and/or pulmonary presentations. Blood Adv. 2020 10 13; 4(19):4873-4886.
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Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas. Am J Surg Pathol. 2020 07; 44(7):881-892.
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Targeted Covalent Inhibition of Telomerase. ACS Chem Biol. 2020 03 20; 15(3):706-717.
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Pan-cancer analysis of whole genomes. Nature. 2020 02; 578(7793):82-93.
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Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis. Am J Respir Crit Care Med. 2019 11 01; 200(9):1154-1163.
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MUC5B variant is associated with visually and quantitatively detected preclinical pulmonary fibrosis. Thorax. 2019 12; 74(12):1131-1139.
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Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 07 15; 200(2):199-208.