"Integration Host Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bacterial proteins that are used by BACTERIOPHAGES to incorporate their DNA into the DNA of the "host" bacteria. They are DNA-binding proteins that function in genetic recombination as well as in transcriptional and translational regulation.
Below are MeSH descriptors whose meaning is more general than "Integration Host Factors".
Below are MeSH descriptors whose meaning is more specific than "Integration Host Factors".
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Below are the most recent publications written about "Integration Host Factors" by people in Profiles.
Static Kinks or Flexible Hinges: Multiple Conformations of Bent DNA Bound to Integration Host Factor Revealed by Fluorescence Lifetime Measurements. J Phys Chem B. 2018 12 13; 122(49):11519-11534.
Two-step interrogation then recognition of DNA binding site by Integration Host Factor: an architectural DNA-bending protein. Nucleic Acids Res. 2018 02 28; 46(4):1741-1755.
Global analysis of ion dependence unveils hidden steps in DNA binding and bending by integration host factor. J Chem Phys. 2013 Sep 28; 139(12):121927.
Mapping the transition state for DNA bending by IHF. J Mol Biol. 2012 May 18; 418(5):300-15.
Binding then bending: a mechanism for wrapping DNA. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19217-8.
Structure-based analysis of HU-DNA binding. J Mol Biol. 2007 Jan 26; 365(4):1005-16.
IHF and HU: flexible architects of bent DNA. Curr Opin Struct Biol. 2004 Feb; 14(1):28-35.
Integration host factor: putting a twist on protein-DNA recognition. J Mol Biol. 2003 Jul 11; 330(3):493-502.
Making DNA do a U-turn: IHF and related proteins. Curr Opin Struct Biol. 1997 Feb; 7(1):86-93.
Crystal structure of an IHF-DNA complex: a protein-induced DNA U-turn. Cell. 1996 Dec 27; 87(7):1295-306.