"Polycomb-Group Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that play a role in CHROMATIN REMODELING. They are best known for silencing HOX GENES and the regulation of EPIGENETIC PROCESSES.
| Descriptor ID |
D063146
|
| MeSH Number(s) |
D05.500.781 D12.776.660.235.600 D12.776.664.235.800 D12.776.930.780.890
|
| Concept/Terms |
Polycomb-Group Proteins- Polycomb-Group Proteins
- Polycomb Group Proteins
- Polycomb Repressive Complex Proteins
- PcG Complex Proteins
Polycomb-Group Protein Complexes- Polycomb-Group Protein Complexes
- Complexes, Polycomb-Group Protein
- Polycomb Group Protein Complexes
- Protein Complexes, Polycomb-Group
|
Below are MeSH descriptors whose meaning is more general than "Polycomb-Group Proteins".
Below are MeSH descriptors whose meaning is more specific than "Polycomb-Group Proteins".
This graph shows the total number of publications written about "Polycomb-Group Proteins" by people in this website by year, and whether "Polycomb-Group Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polycomb-Group Proteins" by people in Profiles.
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Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation. Nat Genet. 2020 06; 52(6):615-625.
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Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia. Genes Dev. 2016 09 01; 30(17):1971-90.
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Epigenetic balance of gene expression by Polycomb and COMPASS families. Science. 2016 Jun 03; 352(6290):aad9780.
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Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/ß-Catenin Transcriptional Activity. Cell Stem Cell. 2016 Jan 07; 18(1):91-103.
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Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion. J Biol Chem. 2015 Mar 27; 290(13):8271-82.
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Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication. Nat Commun. 2014 Apr 14; 5:3649.
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Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation. Science. 2012 Aug 24; 337(6097):971-5.
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Polycomb-repressed genes have permissive enhancers that initiate reprogramming. Cell. 2011 Dec 09; 147(6):1283-94.
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The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors. Cell Cycle. 2010 Jul 01; 9(13):2663-73.
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SETting the stage. Eed-Enx1 leaves an epigenetic signature on the inactive X chromosome. Dev Cell. 2003 Apr; 4(4):445-7.