 Receptors, Notch
"Receptors, Notch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor.
| Descriptor ID |
D051880
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| MeSH Number(s) |
D12.776.543.750.725 D12.776.930.670
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, Notch".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Notch".
This graph shows the total number of publications written about "Receptors, Notch" by people in this website by year, and whether "Receptors, Notch" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 2 | 2 | | 1991 | 0 | 3 | 3 | | 1992 | 0 | 1 | 1 | | 1993 | 0 | 4 | 4 | | 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 4 | 4 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 4 | 4 | | 2006 | 2 | 2 | 4 | | 2007 | 2 | 2 | 4 | | 2008 | 5 | 3 | 8 | | 2009 | 0 | 5 | 5 | | 2010 | 3 | 1 | 4 | | 2011 | 1 | 2 | 3 | | 2012 | 3 | 3 | 6 | | 2013 | 0 | 2 | 2 | | 2014 | 2 | 5 | 7 | | 2015 | 4 | 2 | 6 | | 2016 | 1 | 3 | 4 | | 2017 | 3 | 1 | 4 | | 2018 | 2 | 1 | 3 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Notch" by people in Profiles.
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Krishna BM, Jana S, Singhal J, Horne D, Awasthi S, Salgia R, Singhal SS. Notch signaling in breast cancer: From pathway analysis to therapy. Cancer Lett. 2019 10 01; 461:123-131.
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Cui J, Zhang W, Huang E, Wang J, Liao J, Li R, Yu X, Zhao C, Zeng Z, Shu Y, Zhang R, Yan S, Lei J, Yang C, Wu K, Wu Y, Huang S, Ji X, Li A, Gong C, Yuan C, Zhang L, Liu W, Huang B, Feng Y, An L, Zhang B, Dai Z, Shen Y, Luo W, Wang X, Huang A, Luu HH, Reid RR, Wolf JM, Thinakaran G, Lee MJ, He TC. BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells. Lab Invest. 2019 01; 99(1):58-71.
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Yan Y, Liu F, Han L, Zhao L, Chen J, Olopade OI, He M, Wei M. HIF-2a promotes conversion to a stem cell phenotype and induces chemoresistance in breast cancer cells by activating Wnt and Notch pathways. J Exp Clin Cancer Res. 2018 Oct 19; 37(1):256.
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Hernandez SL, Nelson M, Sampedro GR, Bagrodia N, Defnet AM, Lec B, Emolo J, Kirschner R, Wu L, Biermann H, Shen S, Bubeck Wardenburg J, Kandel JJ. Staphylococcus aureus alpha toxin activates Notch in vascular cells. Angiogenesis. 2019 02; 22(1):197-209.
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Hsu PJ, He C. Making Changes: N6-Methyladenosine-Mediated Decay Drives the Endothelial-to-Hematopoietic Transition. Biochemistry. 2017 11 21; 56(46):6077-6078.
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KleinJan A, Tindemans I, Montgomery JE, Lukkes M, de Bruijn MJW, van Nimwegen M, Bergen I, Moellering RE, Hoogsteden HC, Boon L, Amsen D, Hendriks RW. The Notch pathway inhibitor stapled a-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J Allergy Clin Immunol. 2018 07; 142(1):76-85.e8.
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Semerci F, Choi WT, Bajic A, Thakkar A, Encinas JM, Depreux F, Segil N, Groves AK, Maletic-Savatic M. Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance. Elife. 2017 07 12; 6.
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Qiao Y, Lipovsky C, Hicks S, Bhatnagar S, Li G, Khandekar A, Guzy R, Woo KV, Nichols CG, Efimov IR, Rentschler S. Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice. Circ Res. 2017 Aug 18; 121(5):549-563.
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Sukhotnik I, Coran AG, Pollak Y, Kuhnreich E, Berkowitz D, Saxena AK. Activated Notch signaling cascade is correlated with stem cell differentiation toward absorptive progenitors after massive small bowel resection in a rat. Am J Physiol Gastrointest Liver Physiol. 2017 Sep 01; 313(3):G247-G255.
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Basch ML, Brown RM, Jen HI, Semerci F, Depreux F, Edlund RK, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK. Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife. 2016 12 14; 5.
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