 Protein Carbonylation
"Protein Carbonylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The appearance of carbonyl groups (such as aldehyde or ketone groups) in PROTEINS as the result of several oxidative modification reactions. It is a standard marker for OXIDATIVE STRESS. Carbonylated proteins tend to be more hydrophobic and resistant to proteolysis.
| Descriptor ID |
D050050
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| MeSH Number(s) |
G02.111.087.682 G02.149.115.682 G03.495.710.690
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| Concept/Terms |
Protein Carbonylation- Protein Carbonylation
- Carbonylations, Protein
- Protein Carbonylations
- Carbonylation, Protein
- Protein Carbonyl Formation
- Carbonyl Formation, Protein
- Formation, Protein Carbonyl
- Carbonylated Protein Formation
- Formation, Carbonylated Protein
- Protein Formation, Carbonylated
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Below are MeSH descriptors whose meaning is more general than "Protein Carbonylation".
Below are MeSH descriptors whose meaning is more specific than "Protein Carbonylation".
This graph shows the total number of publications written about "Protein Carbonylation" by people in this website by year, and whether "Protein Carbonylation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 2 | 1 | 3 | | 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "Protein Carbonylation" by people in Profiles.
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Lynch TL, Sivaguru M, Velayutham M, Cardounel AJ, Michels M, Barefield D, Govindan S, dos Remedios C, van der Velden J, Sadayappan S. Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation. Oxid Med Cell Longev. 2015; 2015:424751.
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Madian AG. Redox proteomic investigation of tetracycline-induced steatosis. Proteomics. 2015 Jan; 15(1):8-9.
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Madian AG, Myracle AD, Diaz-Maldonado N, Rochelle NS, Janle EM, Regnier FE. Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins. Anal Chem. 2011 Dec 15; 83(24):9328-36.
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Madian AG, Diaz-Maldonado N, Gao Q, Regnier FE. Oxidative stress induced carbonylation in human plasma. J Proteomics. 2011 Oct 19; 74(11):2395-416.
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Madian AG, Myracle AD, Diaz-Maldonado N, Rochelle NS, Janle EM, Regnier FE. Differential carbonylation of proteins as a function of in vivo oxidative stress. J Proteome Res. 2011 Sep 02; 10(9):3959-72.
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Madian AG, Regnier FE. Proteomic identification of carbonylated proteins and their oxidation sites. J Proteome Res. 2010 Aug 06; 9(8):3766-80.
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Madian AG, Regnier FE. Profiling carbonylated proteins in human plasma. J Proteome Res. 2010 Mar 05; 9(3):1330-43.
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Mahata J, Argos M, Verret W, Kibriya MG, Santella RM, Ahsan H. Effect of selenium and vitamin e supplementation on plasma protein carbonyl levels in patients with arsenic-related skin lesions. Nutr Cancer. 2008; 60(1):55-60.
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