"Protein Carbonylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The appearance of carbonyl groups (such as aldehyde or ketone groups) in PROTEINS as the result of several oxidative modification reactions. It is a standard marker for OXIDATIVE STRESS. Carbonylated proteins tend to be more hydrophobic and resistant to proteolysis.
| Descriptor ID |
D050050
|
| MeSH Number(s) |
G02.111.682 G03.673.690 G07.775.750.750
|
| Concept/Terms |
Protein Carbonylation- Protein Carbonylation
- Carbonylations, Protein
- Protein Carbonylations
- Carbonylated Protein Formation
- Formation, Carbonylated Protein
- Protein Formation, Carbonylated
- Protein Carbonyl Formation
- Carbonyl Formation, Protein
- Formation, Protein Carbonyl
- Carbonylation, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Carbonylation".
Below are MeSH descriptors whose meaning is more specific than "Protein Carbonylation".
This graph shows the total number of publications written about "Protein Carbonylation" by people in this website by year, and whether "Protein Carbonylation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 1 | 3 |
| 2015 | 1 | 1 | 2 |
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Below are the most recent publications written about "Protein Carbonylation" by people in Profiles.
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Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation. Oxid Med Cell Longev. 2015; 2015:424751.
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Redox proteomic investigation of tetracycline-induced steatosis. Proteomics. 2015 Jan; 15(1):8-9.
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Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins. Anal Chem. 2011 Dec 15; 83(24):9328-36.
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Oxidative stress induced carbonylation in human plasma. J Proteomics. 2011 Oct 19; 74(11):2395-416.
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Differential carbonylation of proteins as a function of in vivo oxidative stress. J Proteome Res. 2011 Sep 02; 10(9):3959-72.
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Proteomic identification of carbonylated proteins and their oxidation sites. J Proteome Res. 2010 Aug 06; 9(8):3766-80.
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Profiling carbonylated proteins in human plasma. J Proteome Res. 2010 Mar 05; 9(3):1330-43.
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Effect of selenium and vitamin e supplementation on plasma protein carbonyl levels in patients with arsenic-related skin lesions. Nutr Cancer. 2008; 60(1):55-60.