"Proteostasis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulation of the concentration, folding, interactions, and cellular localization of each of the proteins that comprise the PROTEOME.
| Descriptor ID |
D000074702
|
| MeSH Number(s) |
G02.111.730 G03.816
|
| Concept/Terms |
Proteostasis- Proteostasis
- Proteostases
- Protein Homeostasis
- Homeostases, Protein
- Homeostasis, Protein
- Protein Homeostases
|
Below are MeSH descriptors whose meaning is more general than "Proteostasis".
Below are MeSH descriptors whose meaning is more specific than "Proteostasis".
This graph shows the total number of publications written about "Proteostasis" by people in this website by year, and whether "Proteostasis" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 1 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 4 | 0 | 4 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proteostasis" by people in Profiles.
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The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors. Immunity. 2026 Mar 10; 59(3):717-733.e10.
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Preserve or destroy: Orphan protein proteostasis and the heat shock response. J Cell Biol. 2024 Dec 02; 223(12).
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Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's disease. Life Sci Alliance. 2024 11; 7(11).
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Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias. J Am Heart Assoc. 2024 05 21; 13(10):e030467.
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Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis. Nat Metab. 2024 Feb; 6(2):304-322.
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Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland. JCI Insight. 2023 06 22; 8(12).
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Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers. Cell. 2021 08 19; 184(17):4531-4546.e26.
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Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat Struct Mol Biol. 2021 07; 28(7):614-625.
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Subcellular localization of the J-protein Sis1 regulates the heat shock response. J Cell Biol. 2021 01 04; 220(1).
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PARPs and ADP-ribosylation in RNA biology: from RNA expression and processing to protein translation and proteostasis. Genes Dev. 2020 03 01; 34(5-6):302-320.