Heterotrimeric GTP-Binding Proteins
"Heterotrimeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.
Descriptor ID |
D020962
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MeSH Number(s) |
D08.811.277.040.330.300.200 D12.644.360.360 D12.776.157.325.332 D12.776.476.375 D12.776.543.325
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Concept/Terms |
Heterotrimeric GTP-Binding Proteins- Heterotrimeric GTP-Binding Proteins
- GTP-Binding Proteins, Heterotrimeric
- Heterotrimeric GTP Binding Proteins
- Heterotrimeric G-Proteins
- G-Proteins, Heterotrimeric
- Heterotrimeric G Proteins
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Below are MeSH descriptors whose meaning is more general than "Heterotrimeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Heterotrimeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Heterotrimeric GTP-Binding Proteins" by people in this website by year, and whether "Heterotrimeric GTP-Binding Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 0 | 1 |
2001 | 1 | 1 | 2 |
2002 | 1 | 1 | 2 |
2006 | 2 | 0 | 2 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterotrimeric GTP-Binding Proteins" by people in Profiles.
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ß2 -Adrenergic Receptor Gene Affects the Heart Rate Response of ß-Blockers: Evidence From 3 Clinical Studies. J Clin Pharmacol. 2019 11; 59(11):1462-1470.
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RGS expression in cancer: oncomining the cancer microarray data. J Recept Signal Transduct Res. 2013 Jun; 33(3):166-71.
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Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart. Sci Transl Med. 2011 Sep 14; 3(100):100ra88.
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Non-canonical functions of RGS proteins. Cell Signal. 2010 Sep; 22(9):1274-81.
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Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol. 2006 Aug; 13(8):713-9.
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat Struct Mol Biol. 2006 Aug; 13(8):704-12.
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Novel role of microtubules in thrombin-induced endothelial barrier dysfunction. FASEB J. 2004 Dec; 18(15):1879-90.
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The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression. J Neurochem. 2002 Sep; 82(6):1453-64.
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Expression of alpha subunit of Gs in Escherichia coli. Methods Enzymol. 2002; 344:171-5.
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Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activation. Curr Biol. 2001 Oct 30; 11(21):1686-90.