 Heterotrimeric GTP-Binding Proteins
"Heterotrimeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.
| Descriptor ID |
D020962
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| MeSH Number(s) |
D08.811.277.040.330.300.200 D12.644.360.375 D12.776.157.325.332 D12.776.476.375 D12.776.543.325
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| Concept/Terms |
Heterotrimeric GTP-Binding Proteins- Heterotrimeric GTP-Binding Proteins
- GTP-Binding Proteins, Heterotrimeric
- Heterotrimeric GTP Binding Proteins
- Heterotrimeric G-Proteins
- G-Proteins, Heterotrimeric
- Heterotrimeric G Proteins
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Below are MeSH descriptors whose meaning is more general than "Heterotrimeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Heterotrimeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Heterotrimeric GTP-Binding Proteins" by people in this website by year, and whether "Heterotrimeric GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2000 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 1 | 2 | | 2006 | 2 | 0 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterotrimeric GTP-Binding Proteins" by people in Profiles.
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Shahin MH, Rouby NE, Conrado DJ, Gonzalez D, Gong Y, Lobmeyer MT, Beitelshees AL, Boerwinkle E, Gums JG, Chapman A, Turner ST, Pepine CJ, Cooper-DeHoff RM, Johnson JA. ß2 -Adrenergic Receptor Gene Affects the Heart Rate Response of ß-Blockers: Evidence From 3 Clinical Studies. J Clin Pharmacol. 2019 11; 59(11):1462-1470.
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Sethakorn N, Dulin NO. RGS expression in cancer: oncomining the cancer microarray data. J Recept Signal Transduct Res. 2013 Jun; 33(3):166-71.
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Chakir K, Depry C, Dimaano VL, Zhu WZ, Vanderheyden M, Bartunek J, Abraham TP, Tomaselli GF, Liu SB, Xiang YK, Zhang M, Takimoto E, Dulin N, Xiao RP, Zhang J, Kass DA. Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart. Sci Transl Med. 2011 Sep 14; 3(100):100ra88.
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Sethakorn N, Yau DM, Dulin NO. Non-canonical functions of RGS proteins. Cell Signal. 2010 Sep; 22(9):1274-81.
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Dou Y, Milne TA, Ruthenburg AJ, Lee S, Lee JW, Verdine GL, Allis CD, Roeder RG. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol. 2006 Aug; 13(8):713-9.
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Ruthenburg AJ, Wang W, Graybosch DM, Li H, Allis CD, Patel DJ, Verdine GL. Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex. Nat Struct Mol Biol. 2006 Aug; 13(8):704-12.
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Birukova AA, Birukov KG, Smurova K, Adyshev D, Kaibuchi K, Alieva I, Garcia JG, Verin AD. Novel role of microtubules in thrombin-induced endothelial barrier dysfunction. FASEB J. 2004 Dec; 18(15):1879-90.
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Zhang D, Zhang L, Lou DW, Nakabeppu Y, Zhang J, Xu M. The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression. J Neurochem. 2002 Sep; 82(6):1453-64.
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Yan SZ, Tang WJ. Expression of alpha subunit of Gs in Escherichia coli. Methods Enzymol. 2002; 344:171-5.
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Niu J, Vaiskunaite R, Suzuki N, Kozasa T, Carr DW, Dulin N, Voyno-Yasenetskaya TA. Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activation. Curr Biol. 2001 Oct 30; 11(21):1686-90.
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