"Proteolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cleavage of proteins into smaller peptides or amino acids either by PROTEASES or non-enzymatically (e.g., Hydrolysis). It does not include Protein Processing, Post-Translational.
| Descriptor ID |
D059748
|
| MeSH Number(s) |
G02.111.720 G03.812
|
| Concept/Terms |
Proteolysis- Proteolysis
- Proteolyses
- Protein Degradation
- Degradation, Protein
- Degradations, Protein
- Protein Degradations
Protein Digestion- Protein Digestion
- Digestion, Protein
- Digestions, Protein
- Protein Digestions
|
Below are MeSH descriptors whose meaning is more general than "Proteolysis".
Below are MeSH descriptors whose meaning is more specific than "Proteolysis".
This graph shows the total number of publications written about "Proteolysis" by people in this website by year, and whether "Proteolysis" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 6 | 6 |
| 2012 | 2 | 6 | 8 |
| 2013 | 3 | 4 | 7 |
| 2014 | 3 | 9 | 12 |
| 2015 | 2 | 5 | 7 |
| 2016 | 2 | 5 | 7 |
| 2017 | 1 | 4 | 5 |
| 2018 | 1 | 3 | 4 |
| 2019 | 1 | 8 | 9 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 6 | 7 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proteolysis" by people in Profiles.
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Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes. Cell Host Microbe. 2023 02 08; 31(2):213-227.e9.
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Endocytosis in the axon initial segment maintains neuronal polarity. Nature. 2022 09; 609(7925):128-135.
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Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers. J Clin Invest. 2022 02 15; 132(4).
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HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
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Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature. 2021 12; 600(7888):334-338.
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Simvastatin modulates estrogen signaling in uterine leiomyoma via regulating receptor palmitoylation, trafficking and degradation. Pharmacol Res. 2021 10; 172:105856.
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PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension. FASEB J. 2021 08; 35(8):e21771.
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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis. Cell. 2021 06 10; 184(12):3163-3177.e21.
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Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs. Proc Natl Acad Sci U S A. 2021 04 27; 118(17).
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Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription. Elife. 2021 02 08; 10.