 Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
| Descriptor ID |
D048868
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| MeSH Number(s) |
D12.644.360.024 D12.776.157.057 D12.776.476.024
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in this website by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1994 | 1 | 0 | 1 | | 1995 | 2 | 0 | 2 | | 1996 | 4 | 0 | 4 | | 1997 | 7 | 0 | 7 | | 1998 | 3 | 0 | 3 | | 1999 | 4 | 3 | 7 | | 2000 | 2 | 0 | 2 | | 2001 | 5 | 1 | 6 | | 2002 | 7 | 3 | 10 | | 2003 | 2 | 3 | 5 | | 2004 | 5 | 3 | 8 | | 2005 | 5 | 6 | 11 | | 2006 | 3 | 7 | 10 | | 2007 | 2 | 4 | 6 | | 2008 | 5 | 2 | 7 | | 2009 | 7 | 5 | 12 | | 2010 | 10 | 4 | 14 | | 2011 | 3 | 5 | 8 | | 2012 | 3 | 5 | 8 | | 2013 | 11 | 3 | 14 | | 2014 | 8 | 11 | 19 | | 2015 | 3 | 8 | 11 | | 2016 | 3 | 3 | 6 | | 2017 | 4 | 1 | 5 | | 2018 | 4 | 2 | 6 | | 2019 | 3 | 0 | 3 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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Huang LS, Sudhadevi T, Fu P, Punathil-Kannan PK, Ebenezer DL, Ramchandran R, Putherickal V, Cheresh P, Zhou G, Ha AW, Harijith A, Kamp DW, Natarajan V. Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts. Int J Mol Sci. 2020 Mar 17; 21(6).
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Sheng T, Sun Y, Sun J, Prinz RA, Peng D, Liu X, Xu X. Role of TGF-ß-activated kinase 1 (TAK1) activation in H5N1 influenza A virus-induced c-Jun terminal kinase activation and virus replication. Virology. 2019 11; 537:263-271.
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Ahsan K, Singh N, Rocha M, Huang C, Prince VE. Prickle1 is required for EMT and migration of zebrafish cranial neural crest. Dev Biol. 2019 04 01; 448(1):16-35.
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Andrew RJ, De Rossi P, Nguyen P, Kowalski HR, Recupero AJ, Guerbette T, Krause SV, Rice RC, Laury-Kleintop L, Wagner SL, Thinakaran G. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor BIN1 does not affect amyloid pathology in an AD mouse model. J Biol Chem. 2019 03 22; 294(12):4477-4487.
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Tirosh A, Mukherjee S, Lack J, Gara SK, Wang S, Quezado MM, Keutgen XM, Wu X, Cam M, Kumar S, Patel D, Nilubol N, Tyagi MV, Kebebew E. Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors. Cancer. 2019 04 15; 125(8):1247-1257.
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De Rossi P, Andrew RJ, Musial TF, Buggia-Prevot V, Xu G, Ponnusamy M, Ly H, Krause SV, Rice RC, de l'Estoile V, Valin T, Salem S, Despa F, Borchelt DR, Bindokas VP, Nicholson DA, Thinakaran G. Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models. Brain Pathol. 2019 07; 29(4):485-501.
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Meister-Broekema M, Freilich R, Jagadeesan C, Rauch JN, Bengoechea R, Motley WW, Kuiper EFE, Minoia M, Furtado GV, van Waarde MAWH, Bird SJ, Rebelo A, Zuchner S, Pytel P, Scherer SS, Morelli FF, Carra S, Weihl CC, Bergink S, Gestwicki JE, Kampinga HH. Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks. Nat Commun. 2018 12 17; 9(1):5342.
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Laroumanie F, Korneva A, Bersi MR, Alexander MR, Xiao L, Zhong X, Van Beusecum JP, Chen Y, Saleh MA, McMaster WG, Gavulic KA, Dale BL, Zhao S, Guo Y, Shyr Y, Perrien DS, Cox NJ, Curci JA, Humphrey JD, Madhur MS. LNK deficiency promotes acute aortic dissection and rupture. JCI Insight. 2018 10 18; 3(20).
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Hong X, Jeyifous O, Ronilo M, Marshall J, Green WN, Standley S. A novel function for the ER retention signals in the C-terminus of kainate receptor subunit, GluK5. Biochim Biophys Acta Mol Cell Res. 2019 03; 1866(3):459-473.
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Maldonado L, Brait M, Izumchenko E, Begum S, Chatterjee A, Sen T, Loyo M, Barbosa A, Poeta ML, Makarev E, Zhavoronkov A, Fazio VM, Angioli R, Rabitti C, Ongenaert M, Van Criekinge W, Noordhuis MG, de Graeff P, Wisman GBA, van der Zee AGJ, Hoque MO. Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1. Cancer Lett. 2018 10 01; 433:242-251.
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