 Proto-Oncogene Proteins c-bcr
"Proto-Oncogene Proteins c-bcr" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proto-oncogene protein bcr is a serine-threonine kinase that functions as a negative regulator of CELL PROLIFERATION and NEOPLASTIC CELL TRANSFORMATION. It is commonly fused with cellular abl protein to form BCR-ABL FUSION PROTEINS in PHILADELPHIA CHROMOSOME positive LEUKEMIA patients.
| Descriptor ID |
D051562
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| MeSH Number(s) |
D08.811.913.696.620.682.700.759 D12.776.624.664.700.171
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| Concept/Terms |
Proto-Oncogene Proteins c-bcr- Proto-Oncogene Proteins c-bcr
- Proto Oncogene Proteins c bcr
- c-bcr, Proto-Oncogene Proteins
- Breakpoint Cluster Region Protein
- Proto-Oncogene Protein c-bcr
- Proto Oncogene Protein c bcr
- c-bcr, Proto-Oncogene Protein
- c-bcr Proto-Oncogene Proteins
- Proto-Oncogene Proteins, c-bcr
- c bcr Proto Oncogene Proteins
- Proto-Oncogene Protein bcr
- Proto Oncogene Protein bcr
- bcr Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcr
- bcr Proto Oncogene Proteins
- c-bcr Proteins
- Proteins, c-bcr
- c bcr Proteins
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-bcr".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-bcr".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-bcr" by people in this website by year, and whether "Proto-Oncogene Proteins c-bcr" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-bcr" by people in Profiles.
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Yenamandra AK, Kaviany S, Borinstein SC, Friedman DL, Kovach AE. BCR-ABL1-like B-Lymphoblastic Leukemia/Lymphoma with FOXP1-ABL1 Rearrangement: Comprehensive Laboratory Identification Allowing Tyrosine Kinase Inhibitor Use. Lab Med. 2019 Oct 10; 50(4):401-405.
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Komatsu M, Wheeler HE, Chung S, Low SK, Wing C, Delaney SM, Gorsic LK, Takahashi A, Kubo M, Kroetz DL, Zhang W, Nakamura Y, Dolan ME. Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy. Clin Cancer Res. 2015 Oct 01; 21(19):4337-46.
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Shao L, Miller S, Keller-Ramey J, Zhang Y, Roulston D. Cytogenetic, fluorescence in situ hybridization, and genomic array characterization of chronic myeloid leukemia with cryptic BCR-ABL1 fusions. Cancer Genet. 2015 Jul-Aug; 208(7-8):396-403.
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Meng W, Yunk L, Wang LS, Maganty A, Xue E, Cohen PL, Eisenberg RA, Weigert MG, Mancini SJ, Prak ET. Selection of individual VH genes occurs at the pro-B to pre-B cell transition. J Immunol. 2011 Aug 15; 187(4):1835-44.
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Clybouw C, Hadji A, ElMchichi B, Auffredou MT, Leca G, Vazquez A. BimL upregulation induced by BCR cross-linking in BL41 Burkitt's lymphoma results from a splicing mechanism of the BimEL mRNA. Biochem Biophys Res Commun. 2009 May 22; 383(1):32-6.
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Przepiorka D, Khouri I, Thall P, Mehra R, Lee MS, Ippoliti C, Giralt S, Gajewski J, van Besien K, Andersson B, Körbling M, Deisseroth AB, Champlin R. Thiotepa, busulfan and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced chronic myelogenous leukemia. Bone Marrow Transplant. 1999 May; 23(10):977-81.
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Ong ST, Hackbarth ML, Degenstein LC, Baunoch DA, Anastasi J, McKeithan TW. Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice. Oncogene. 1998 May 07; 16(18):2333-43.
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Stock W, Westbrook CA, Peterson B, Arthur DC, Szatrowski TP, Silver RT, Sher DA, Wu D, Le Beau MM, Schiffer CA, Bloomfield CD. Value of molecular monitoring during the treatment of chronic myeloid leukemia: a Cancer and Leukemia Group B study. J Clin Oncol. 1997 Jan; 15(1):26-36.
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Riggins GJ, Sherman SL, Phillips CN, Stock W, Westbrook CA, Warren ST. CGG-repeat polymorphism of the BCR gene rules out predisposing alleles leading to the Philadelphia chromosome. Genes Chromosomes Cancer. 1994 Feb; 9(2):141-4.
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