"Citric Acid Cycle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of oxidative reactions in the breakdown of acetyl units derived from GLUCOSE; FATTY ACIDS; or AMINO ACIDS by means of tricarboxylic acid intermediates. The end products are CARBON DIOXIDE, water, and energy in the form of phosphate bonds.
| Descriptor ID |
D002952
|
| MeSH Number(s) |
G02.111.165 G03.295.342 G03.493.170
|
| Concept/Terms |
Citric Acid Cycle- Citric Acid Cycle
- Citric Acid Cycles
- Cycle, Citric Acid
- Cycles, Citric Acid
- Tricarboxylic Acid Cycle
- Cycle, Tricarboxylic Acid
- Cycles, Tricarboxylic Acid
- Tricarboxylic Acid Cycles
- Krebs Cycle
- Cycle, Krebs
|
Below are MeSH descriptors whose meaning is more general than "Citric Acid Cycle".
Below are MeSH descriptors whose meaning is more specific than "Citric Acid Cycle".
This graph shows the total number of publications written about "Citric Acid Cycle" by people in this website by year, and whether "Citric Acid Cycle" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 1 | 2 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 4 | 4 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 2 | 2 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Citric Acid Cycle" by people in Profiles.
-
High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non-Small Cell Lung Cancer in Patients. Cancer Discov. 2025 Apr 02; 15(4):702-716.
-
Metabolic pathway analysis using stable isotopes in patients with cancer. Nat Rev Cancer. 2023 Dec; 23(12):863-878.
-
Complex regulation in a Comamonas platform for diverse aromatic carbon metabolism. Nat Chem Biol. 2023 05; 19(5):651-662.
-
Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells. Cell Chem Biol. 2022 07 21; 29(7):1200-1208.e6.
-
Compartmentalized metabolism supports midgestation mammalian development. Nature. 2022 04; 604(7905):349-353.
-
Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment. Nat Metab. 2021 11; 3(11):1484-1499.
-
Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival. Blood Cancer Discov. 2022 01; 3(1):50-65.
-
The therapeutic implications of immunosuppressive tumor aerobic glycolysis. Cell Mol Immunol. 2022 01; 19(1):46-58.
-
Mitochondrial NADP(H) generation is essential for proline biosynthesis. Science. 2021 05 28; 372(6545):968-972.
-
Proline biosynthesis is a vent for TGFß-induced mitochondrial redox stress. EMBO J. 2020 04 15; 39(8):e103334.