"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
| Descriptor ID |
D015854
|
| MeSH Number(s) |
G02.111.905 G05.308.850 G07.690.773.998
|
| Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
|
Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 0 | 4 | 4 |
| 1995 | 0 | 2 | 2 |
| 1996 | 1 | 7 | 8 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 8 | 8 |
| 1999 | 0 | 7 | 7 |
| 2000 | 1 | 8 | 9 |
| 2001 | 2 | 9 | 11 |
| 2002 | 2 | 16 | 18 |
| 2003 | 4 | 19 | 23 |
| 2004 | 6 | 43 | 49 |
| 2005 | 2 | 20 | 22 |
| 2006 | 1 | 25 | 26 |
| 2007 | 5 | 19 | 24 |
| 2008 | 1 | 23 | 24 |
| 2009 | 1 | 23 | 24 |
| 2010 | 6 | 19 | 25 |
| 2011 | 3 | 28 | 31 |
| 2012 | 3 | 29 | 32 |
| 2013 | 7 | 14 | 21 |
| 2014 | 4 | 20 | 24 |
| 2015 | 1 | 20 | 21 |
| 2016 | 3 | 10 | 13 |
| 2017 | 4 | 21 | 25 |
| 2018 | 3 | 22 | 25 |
| 2019 | 0 | 9 | 9 |
| 2020 | 2 | 16 | 18 |
| 2021 | 1 | 8 | 9 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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TLR4 activation induces inflammatory vascular permeability via Dock1 targeting and NOX4 upregulation. Biochim Biophys Acta Mol Basis Dis. 2022 12 01; 1868(12):166562.
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Targeted polyelectrolyte complex micelles treat vascular complications in?vivo. Proc Natl Acad Sci U S A. 2021 12 14; 118(50).
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Laminin-a4 Is Upregulated in Both Human and Murine Models of Obesity. Front Endocrinol (Lausanne). 2021; 12:698621.
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Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM). Br J Cancer. 2021 08; 125(4):582-592.
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Hypoxia Preconditioning Promotes the Proliferation and Migration of Human Urine-Derived Stem Cells in Chronically Injured Liver of Mice by Upregulating CXCR4. Stem Cells Dev. 2021 05 15; 30(10):526-536.
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Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
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Serum alpha-fetoprotein and clinical outcomes in patients with advanced hepatocellular carcinoma treated with ramucirumab. Br J Cancer. 2021 04; 124(8):1388-1397.
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Dysregulated microRNA expression in IL-4 transgenic mice, an animal model of atopic dermatitis. Arch Dermatol Res. 2021 Dec; 313(10):837-846.
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Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin. Nat Immunol. 2021 02; 22(2):154-165.
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Falcarindiol and dichloromethane fraction are bioactive components in Oplopanax elatus: Colorectal cancer chemoprevention via induction of apoptosis and G2/M cell cycle arrest mediated by cyclin A upregulation. J Appl Biomed. 2021; 19(2):113-124.